Students in the Biomedical Research Minor work on real research projects that are potentially publishable. As of September 2022, there are 463 publications in peer-reviewed journals with one or more of our students or alumni as co-authors. For a list of student authors, click here.

 

2022   2021   2020   2019   2018   2017   2016   2015   2014   2013   2012   2011   2010   2009   2008

2022

Cambou, M. C.; Liu, C. M.; Mok, T.; Fajardo-Martinez, V.; Paiola, S. G.; Ibarrondo, F. J.; Kerin, T.; Fuller, T.; Tobin, N. H.; Garcia, G.; Bhattacharya, D.; Aldrovandi, G. M.; Arumugaswami, V.; Foo, S. S.; Jung, J. U.; Vasconcelos, Z.; Brasil, P.; Brendolin, M.; Yang, O.; Rao, R.; Nielsen-Saines, K. Longitudinal Evaluation of Antibody Persistence in Mother-Infant Dyads Following SARS-CoV-2 Infection in Pregnancy. J Infect Dis 2022, jiac366.

Bermudez, A.; Gonzalez, Z.; Zhao, B.; Salter, E.; Liu, X.; Ma, L.; Jawed, M. K.; Hsieh, C.-J.; Lin, N. Y. C. Supracellular Measurement of Spatially Varying Mechanical Heterogeneities in Live Monolayers. Biophys J 2022, S0006-3495(22)00684-1.

Katz, S. S.; Barker, T. J.; Maul-Newby, H. M.; Sparacio, A. P.; Nguyen, K. C. Q.; Maybrun, C. L.; Belfi, A.; Cohen, J. D.; Hall, D. H.; Sundaram, M. V.; Frand, A. R. A Transient Apical Extracellular Matrix Relays Cytoskeletal Patterns to Shape Permanent Acellular Ridges on the Surface of Adult C. Elegans. PLoS Genet 2022, 18 (8), e1010348.

Li, Y.-R.; Zeng, S.; Dunn, Z. S.; Zhou, Y.; Li, Z.; Yu, J.; Wang, Y.-C.; Ku, J.; Cook, N.; Kramer, A.; Yang, L. Off-the-Shelf Third-Party HSC-Engineered INKT Cells for Ameliorating GvHD While Preserving GvL Effect in the Treatment of Blood Cancers. iScience 2022, 25 (9), 104859.

Cho, N. S.; Hagiwara, A.; Eldred, B. S. C.; Raymond, C.; Wang, C.; Sanvito, F.; Lai, A.; Nghiemphu, P.; Salamon, N.; Steelman, L.; Hassan, I.; Cloughesy, T. F.; Ellingson, B. M. Early Volumetric, Perfusion, and Diffusion MRI Changes after Mutant Isocitrate Dehydrogenase (IDH) Inhibitor Treatment in IDH1-Mutant Gliomas. Neurooncol Adv 2022, 4 (1), vdac124.

Deshpande, S. A.; Rohrbach, E. W.; Asuncion, J. D.; Harrigan, J.; Eamani, A.; Schlingmann, E. H.; Suto, D. J.; Lee, P.-T.; Schweizer, F. E.; Bellen, H. J.; Krantz, D. E. Regulation of Drosophila Oviduct Muscle Contractility by Octopamine.

Murtha, K. E.; Yang, Y.; Ceriani, F.; Jeng, J.-Y.; Climer, L. K.; Jones, F.; Charles, J.; Devana, S. K.; Hornak, A. J.; Marcotti, W.; Simmons, D. D. Oncomodulin (OCM) Uniquely Regulates Calcium Signaling in Neonatal Cochlear Outer Hair Cells. Cell Calcium 2022, 105, 102613.

Xiao, H.; Duo, L.; Zhen, J.; Wang, H.; Guo, Z. Static and Dynamic Disorder in Aβ40 Fibrils. Biochem Biophys Res Commun 2022, 610, 107–112.

Lowe, M. G.; Yen, M.-R.; Hsu, F.-M.; Hosohama, L.; Hu, Z.; Chitiashvili, T.; Hunt, T. J.; Gorgy, I.; Bernard, M.; Wamaitha, S. E.; Chen, P.-Y.; Clark, A. T. EED Is Required for Mouse Primordial Germ Cell Differentiation in the Embryonic Gonad. Dev Cell 2022, 57 (12), 1482-1495.e5.

Lee, D.; Rosenthal, C. J.; Penn, N. E.; Dunn, Z. S.; Zhou, Y.; Yang, L. Human Γδ T Cell Subsets and Their Clinical Applications for Cancer Immunotherapy. Cancers (Basel) 2022, 14 (12), 3005.

Shen, Y.; Zhou, M.; Cai, D.; Filho, D. A.; Fernandes, G.; Cai, Y.; de Sousa, A. F.; Tian, M.; Kim, N.; Lee, J.; Necula, D.; Zhou, C.; Li, S.; Salinas, S.; Liu, A.; Kang, X.; Kamata, M.; Lavi, A.; Huang, S.; Silva, T.; Do Heo, W.; Silva, A. J. CCR5 Closes the Temporal Window for Memory Linking. Nature 2022, 606 (7912), 146–152.

Huang, R.; Worrell, J.; Garner, E.; Wang, S.; Homsey, T.; Xu, B.; Galer, E. L.; Zhou, Y.; Tavakol, S.; Daneshvar, M.; Le, T.; Vinters, H. V.; Salamon, N.; McArthur, D. L.; Nuwer, M. R.; Wu, I.; Leiter, J. C.; Lu, D. C. Epidural Electrical Stimulation of the Cervical Spinal Cord Opposes Opioid-Induced Respiratory Depression. J Physiol 2022, 600 (12), 2973–2999.

Henrich, M.; Ha, P.; Wang, Y.; Ting, K.; Stodieck, L.; Soo, C.; Adams, J. S.; Chun, R. Alternative Splicing Diversifies the Skeletal Muscle Transcriptome during Prolonged Spaceflight. Skelet Muscle 2022, 12 (1), 11.

Scaramella, C.; Alzagatiti, J. B.; Creighton, C.; Mankatala, S.; Licea, F.; Winter, G. M.; Emtage, J.; Wisnieski, J. R.; Salazar, L.; Hussain, A.; Lee, F. M.; Mammootty, A.; Mammootty, N.; Aldujaili, A.; Runnberg, K. A.; Hernandez, D.; Zimmerman-Thompson, T.; Makwana, R.; Rouvere, J.; Tahmasebi, Z.; Zavradyan, G.; Campbell, C. S.; Komaranchath, M.; Carmona, J.; Trevitt, J.; Glanzman, D.; Roberts, A. C. Bisphenol A Exposure Induces Sensory Processing Deficits in Larval Zebrafish during Neurodevelopment. eNeuro 2022, 9 (3), ENEURO.0020-22.2022.

Bu, M. T.; Chandrasekhar, P.; Ding, L.; Hugo, W. The Roles of TGF-β and VEGF Pathways in the Suppression of Antitumor Immunity in Melanoma and Other Solid Tumors. Pharmacol Ther 2022, 240, 108211.

Huang, R.; Nikooyan, A. A.; Moore, L. D.; Zdunowski, S.; Morikawa, E.; Sierro, T.; Sayenko, D.; Gad, P.; Homsey, T.; Le, T.; Madhavan, M. A.; Abdelshahid, M.; Abdelshahid, M.; Zhou, Y.; Nuwer, M. R.; Sarrafzadeh, M.; Edgerton, V. R.; Leiter, J. C.; Lu, D. C. Minimal Handgrip Force Is Needed for Transcutaneous Electrical Stimulation to Improve Hand Functions of Patients with Severe Spinal Cord Injury. Sci Rep 2022, 12 (1), 7733.

O’Brien, N. A.; Huang, H. K. T.; McDermott, M. S. J.; Madrid, A. M.; Luo, T.; Ayala, R.; Issakhanian, S.; Gong, K. W.; Lu, M.; Zhang, J.; Slamon, D. J. Tucatinib Has Selective Activity in HER2-Positive Cancers and Significant Combined Activity with Approved and Novel Breast Cancer-Targeted Therapies. Mol Cancer Ther 2022, 21 (5), 751–761.

Zieba, J.; Forlenza, K. N.; Heard, K.; Martin, J. H.; Bosakova, M.; Cohn, D. H.; Robertson, S. P.; Krejci, P.; Krakow, D. Intervertebral Disc Degeneration Is Rescued by TGFβ/BMP Signaling Modulation in an Ex Vivo Filamin B Mouse Model. Bone Res 2022, 10 (1), 37.

Song, K.; Minami, J. K.; Huang, A.; Dehkordi, S. R.; Lomeli, S. H.; Luebeck, J.; Goodman, M. H.; Moriceau, G.; Krijgsman, O.; Dharanipragada, P.; Ridgley, T.; Crosson, W. P.; Salazar, J.; Pazol, E.; Karin, G.; Jayaraman, R.; Balanis, N. G.; Alhani, S.; Sheu, K.; Ten Hoeve, J.; Palermo, A.; Motika, S. E.; Senaratne, T. N.; Paraiso, K. H.; Hergenrother, P. J.; Rao, P. N.; Multani, A. S.; Peeper, D. S.; Bafna, V.; Lo, R. S.; Graeber, T. G. Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges. Cancer Discov 2022, 12 (4), 1046–1069.

Goldman, J.; Hagiwara, A.; Yao, J.; Raymond, C.; Ong, C.; Bakhti, R.; Kwon, E.; Farhat, M.; Torres, C.; Erickson, L. G.; Curl, B. J.; Lee, M.; Pope, W. B.; Salamon, N.; Nghiemphu, P. L.; Ji, M.; Eldred, B. S.; Liau, L. M.; Lai, A.; Cloughesy, T. F.; Chung, C.; Ellingson, B. M. Paradoxical Association Between Relative Cerebral Blood Volume Dynamics Following Chemoradiation and Increased Progression-Free Survival in Newly Diagnosed IDH Wild-Type MGMT Promoter Methylated Glioblastoma With Measurable Disease. Front Oncol 2022, 12, 849993.

Lam, K.; Eldred, B. S. C.; Kevan, B.; Pianka, S.; Eldred, B. A.; Zapanta Rinonos, S.; Yong, W. H.; Liau, L. M.; Nghiemphu, P. L.; Cloughesy, T. F.; Green, R. M.; Lai, A. Prognostic Value of O 6-Methylguanine-DNA Methyltransferase Methylation in Isocitrate Dehydrogenase Mutant Gliomas. Neurooncol Adv 2022, 4 (1), vdac030.

Purandare, C. S.; Dhingra, S.; Rios, R.; Vuong, C.; To, T.; Hachisuka, A.; Choudhary, K.; Mehta, M. R. Moving Bar of Light Evokes Vectorial Spatial Selectivity in the Immobile Rat Hippocampus. Nature 2022, 602 (7897), 461–467.

Potok, M. E.; Zhong, Z.; Picard, C. L.; Liu, Q.; Do, T.; Jacobsen, C. E.; Sakr, O.; Naranbaatar, B.; Thilakaratne, R.; Khnkoyan, Z.; Purl, M.; Cheng, H.; Vervaet, H.; Feng, S.; Rayatpisheh, S.; Wohlschlegel, J. A.; O’Malley, R. C.; Ecker, J. R.; Jacobsen, S. E. The Role of ATXR6 Expression in Modulating Genome Stability and Transposable Element Repression in Arabidopsis. Proc Natl Acad Sci U S A 2022, 119 (3), e2115570119.

Choi, D.; Gonzalez, Z.; Ho, S. Y.; Bermudez, A.; Lin, N. Y. C. Cell-Cell Adhesion Impacts Epithelia Response to Substrate Stiffness: Morphology and Gene Expression. Biophys J 2022, 121 (2), 336–346.

Termini, C. M.; Pang, A.; Li, M.; Fang, T.; Chang, V. Y.; Chute, J. P. Syndecan-2 Enriches for Hematopoietic Stem Cells and Regulates Stem Cell Repopulating Capacity. Blood 2022, 139 (2), 188–204.

Barry, J.; Bui, M. T. N.; Levine, M. S.; Cepeda, C. Synaptic Pathology in Huntington’s Disease: Beyond the Corticostriatal Pathway. Neurobiol Dis 2022, 162, 105574.

Miranda, M.; Avila, I.; Esparza, J.; Shwartz, Y.; Hsu, Y.-C.; Berdeaux, R.; Lowry, W. E. Defining a Role for G-Protein Coupled Receptor/CAMP/CRE-Binding Protein Signaling in Hair Follicle Stem Cell Activation. J Invest Dermatol 2022, 142 (1), 53-64.e3.

Pezhouman, A.; Nguyen, N. B.; Shevtsov, A.; Qiao, R.; Ardehali, R. In Vitro Generation of Heart Field Specific Cardiomyocytes. Methods Mol Biol 2022, 2429, 257–267. https://doi.org/10.1007/978-1-0716-1979-7_17.

 

2021

Pezhouman, A.; Nguyen, N. B.; Sercel, A. J.; Nguyen, T. L.; Daraei, A.; Sabri, S.; Chapski, D. J.; Zheng, M.; Patananan, A. N.; Ernst, J.; Plath, K.; Vondriska, T. M.; Teitell, M. A.; Ardehali, R. Transcriptional, Electrophysiological, and Metabolic Characterizations of HESC-Derived First and Second Heart Fields Demonstrate a Potential Role of TBX5 in Cardiomyocyte Maturation. Front Cell Dev Biol 2021, 9, 787684.

Spratford, C. M.; Goins, L. M.; Chi, F.; Girard, J. R.; Macias, S. N.; Ho, V. W.; Banerjee, U. Intermediate Progenitor Cells Provide a Transition between Hematopoietic Progenitors and Their Differentiated Descendants. Development 2021, 148 (24), dev200216.

Markaki, Y.; Chong, J. G.; Wang, Y.; Jacobson, E. C.; Luong, C.; Tan, S. Y. X.; Jachowicz, J. W.; Strehle, M.; Maestrini, D.; Banerjee, A. K.; Mistry, B. A.; Dror, I.; Dossin, F.; Schӧneberg, J.; Heard, E.; Guttman, M.; Chou, T.; Plath, K. Xist Nucleates Local Protein Gradients to Propagate Silencing across the X Chromosome. Cell 2021, 184 (25), 6212.

Sun, L.; Lai, T. J.; Prins, R. M. Is There a Role for Neoadjuvant Anti-PD-1 Therapies in Glioma? Curr Opin Neurol 2021, 34 (6), 834–839.

Chakravarty, N.; Senthilnathan, T.; Paiola, S.; Gyani, P.; Castillo Cario, S.; Urena, E.; Jeysankar, A.; Jeysankar, P.; Ignatius Irudayam, J.; Natesan Subramanian, S.; Lavretsky, H.; Joshi, S.; Garcia, G.; Ramaiah, A.; Arumugaswami, V. Neurological Pathophysiology of SARS-CoV-2 and Pandemic Potential RNA Viruses: A Comparative Analysis. FEBS Lett 2021, 595 (23), 2854–2871.

Termini, C. M.; Pang, A.; Fang, T.; Roos, M.; Chang, V. Y.; Zhang, Y.; Setiawan, N. J.; Signaevskaia, L.; Li, M.; Kim, M. M.; Tabibi, O.; Lin, P. K.; Sasine, J. P.; Chatterjee, A.; Murali, R.; Himburg, H. A.; Chute, J. P. Neuropilin 1 Regulates Bone Marrow Vascular Regeneration and Hematopoietic Reconstitution. Nat Commun 2021, 12 (1), 6990.

Li, Y.-R.; Zhou, Y.; Kim, Y. J.; Zhu, Y.; Ma, F.; Yu, J.; Wang, Y.-C.; Chen, X.; Li, Z.; Zeng, S.; Wang, X.; Lee, D.; Ku, J.; Tsao, T.; Hardoy, C.; Huang, J.; Cheng, D.; Montel-Hagen, A.; Seet, C. S.; Crooks, G. M.; Larson, S. M.; Sasine, J. P.; Wang, X.; Pellegrini, M.; Ribas, A.; Kohn, D. B.; Witte, O.; Wang, P.; Yang, L. Development of Allogeneic HSC-Engineered INKT Cells for off-the-Shelf Cancer Immunotherapy. Cell Rep Med 2021, 2 (11), 100449.

Movassaghi, C. S.; Perrotta, K. A.; Yang, H.; Iyer, R.; Cheng, X.; Dagher, M.; Fillol, M. A.; Andrews, A. M. Simultaneous Serotonin and Dopamine Monitoring across Timescales by Rapid Pulse Voltammetry with Partial Least Squares Regression. Anal Bioanal Chem 2021, 413 (27), 6747–6767.

Bonitto, K.; Sarathy, K.; Atai, K.; Mitra, M.; Coller, H. A. Is There a Histone Code for Cellular Quiescence? Front Cell Dev Biol 2021, 9, 739780.

Girard, J. R.; Goins, L. M.; Vuu, D. M.; Sharpley, M. S.; Spratford, C. M.; Mantri, S. R.; Banerjee, U. Paths and Pathways That Generate Cell-Type Heterogeneity and Developmental Progression in Hematopoiesis. Elife 2021, 10, e67516.

Yau, T.-Y.; Sander, W.; Eidson, C.; Courey, A. J. SUMO Interacting Motifs: Structure and Function. Cells 2021, 10 (11), 2825.

Luu, A. P.; Yao, Z.; Ramachandran, S.; Azzopardi, S. A.; Miles, L. A.; Schneider, W. M.; Hoffmann, H.-H.; Bozzacco, L.; Garcia, G.; Gong, D.; Damoiseaux, R.; Tang, H.; Morizono, K.; Rudin, C. M.; Sun, R.; Arumugaswami, V.; Poirier, J. T.; MacDonald, M. R.; Rice, C. M.; Li, M. M. H. A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry. Viruses 2021, 13 (11), 2113.

Oikonomou, K. D.; Donzis, E. J.; Bui, M. T. N.; Cepeda, C.; Levine, M. S. Calcium Dysregulation and Compensation in Cortical Pyramidal Neurons of the R6/2 Mouse Model of Huntington’s Disease. J Neurophysiol 2021, 126 (4), 1159–1171.

Samarasinghe, R. A.; Miranda, O. A.; Buth, J. E.; Mitchell, S.; Ferando, I.; Watanabe, M.; Allison, T. F.; Kurdian, A.; Fotion, N. N.; Gandal, M. J.; Golshani, P.; Plath, K.; Lowry, W. E.; Parent, J. M.; Mody, I.; Novitch, B. G. Identification of Neural Oscillations and Epileptiform Changes in Human Brain Organoids. Nat Neurosci 2021, 24 (10), 1488–1500.

Dumesic, D. A.; Tulberg, A.; McNamara, M.; Grogan, T. R.; Abbott, D. H.; Naik, R.; Lu, G.; Chazenbalk, G. D. Serum Testosterone to Androstenedione Ratio Predicts Metabolic Health in Normal-Weight Polycystic Ovary Syndrome Women. J Endocr Soc 2021, 5 (11), bvab158.

Burton, N. R.; Kim, P.; Backus, K. M. Photoaffinity Labelling Strategies for Mapping the Small Molecule-Protein Interactome. Org Biomol Chem 2021, 19 (36), 7792–7809.

Lynn, N. A.; Martinez, E.; Nguyen, H.; Torres, J. Z. The Mammalian Family of Katanin Microtubule-Severing Enzymes. Front Cell Dev Biol 2021, 9, 692040.

Basu, R.; Eichhorn, C. D.; Cheng, R.; Peterson, R. D.; Feigon, J. Structure of S. Pombe Telomerase Protein Pof8 C-Terminal Domain Is an XRRM Conserved among LARP7 Proteins. RNA Biol 2021, 18 (8), 1181–1192.

Hancock, G. V.; Wamaitha, S. E.; Peretz, L.; Clark, A. T. Mammalian Primordial Germ Cell Specification. Development 2021, 148 (6), dev189217.

Zhao, Y.; James, N. A.; Beshay, A. R.; Chang, E. E.; Lin, A.; Bashar, F.; Wassily, A.; Nguyen, B.; Nguyen, T. P. Adult Zebrafish Ventricular Electrical Gradients as Tissue Mechanisms of ECG Patterns under Baseline vs. Oxidative Stress. Cardiovasc Res 2021, 117 (8), 1891–1907.

Dumesic, D. A.; Tulberg, A.; Leung, K. L.; Fisch, S. C.; Grogan, T. R.; Abbott, D. H.; Naik, R.; Chazenbalk, G. D. Accelerated Subcutaneous Abdominal Stem Cell Adipogenesis Predicts Insulin Sensitivity in Normal-Weight Women with Polycystic Ovary Syndrome. Fertil Steril 2021, 116 (1), 232–242.

Zeiger, W. A.; Marosi, M.; Saggi, S.; Noble, N.; Samad, I.; Portera-Cailliau, C. Barrel Cortex Plasticity after Photothrombotic Stroke Involves Potentiating Responses of Pre-Existing Circuits but Not Functional Remapping to New Circuits. Nat Commun 2021, 12 (1), 3972.

Ghoshal, B.; Picard, C. L.; Vong, B.; Feng, S.; Jacobsen, S. E. CRISPR-Based Targeting of DNA Methylation in Arabidopsis Thaliana by a Bacterial CG-Specific DNA Methyltransferase. Proc Natl Acad Sci U S A 2021, 118 (23), e2125016118.

Aros, C. J.; Pantoja, C. J.; Gomperts, B. N. Wnt Signaling in Lung Development, Regeneration, and Disease Progression. Commun Biol 2021, 4 (1), 601.

Wang, X.; Li, B.; Kim, Y. J.; Wang, Y.-C.; Li, Z.; Yu, J.; Zeng, S.; Ma, X.; Choi, I. Y.; Di Biase, S.; Smith, D. J.; Zhou, Y.; Li, Y.-R.; Ma, F.; Huang, J.; Clarke, N.; To, A.; Gong, L.; Pham, A. T.; Moon, H.; Pellegrini, M.; Yang, L. Targeting Monoamine Oxidase A for T Cell-Based Cancer Immunotherapy. Sci Immunol 2021, 6 (59), eabh2383.

He, Y.; Wang, Y.; Liu, B.; Helmling, C.; Sušac, L.; Cheng, R.; Zhou, Z. H.; Feigon, J. Structures of Telomerase at Several Steps of Telomere Repeat Synthesis. Nature 2021, 593 (7859), 454–459.

Hildreth, A. D.; Ma, F.; Wong, Y. Y.; Sun, R.; Pellegrini, M.; O’Sullivan, T. E. Single-Cell Sequencing of Human White Adipose Tissue Identifies New Cell States in Health and Obesity. Nat Immunol 2021, 22 (5), 639–653.

Llorente, I. L.; Xie, Y.; Mazzitelli, J. A.; Hatanaka, E. A.; Cinkornpumin, J.; Miller, D. R.; Lin, Y.; Lowry, W. E.; Carmichael, S. T. Patient-Derived Glial Enriched Progenitors Repair Functional Deficits Due to White Matter Stroke and Vascular Dementia in Rodents. Sci Transl Med 2021, 13 (590), eaaz6747.

Fajardo, V. M.; Feng, I.; Chen, B. Y.; Perez-Ramirez, C. A.; Shi, B.; Clark, P.; Tian, R.; Lien, C.-L.; Pellegrini, M.; Christofk, H.; Nakano, H.; Nakano, A. GLUT1 Overexpression Enhances Glucose Metabolism and Promotes Neonatal Heart Regeneration. Sci Rep 2021, 11 (1), 8669.

Termini, C. M.; Pang, A.; Batton, D. M.; Chute, J. P. Proteoglycans Regulate Protein Tyrosine Phosphatase Receptor σ Organization on Hematopoietic Stem/Progenitor Cells. Exp Hematol 2021, 96, 44–51.

Quintero-Rivera, F.; Eno, C. C.; Sutanto, C.; Jones, K. L.; Nowaczyk, M. J. M.; Wong, D.; Earl, D.; Mirzaa, G.; Beck, A.; Martinez-Agosto, J. A. 5q35 Duplication Presents with Psychiatric and Undergrowth Phenotypes Mediated by NSD1 Overexpression and MTOR Signaling Downregulation. Hum Genet 2021, 140 (4), 681–690. https://doi.org/10.1007/s00439-020-02240-5.

Hardcastle, B. J.; Omoto, J. J.; Kandimalla, P.; Nguyen, B.-C. M.; Keleş, M. F.; Boyd, N. K.; Hartenstein, V.; Frye, M. A. A Visual Pathway for Skylight Polarization Processing in Drosophila. Elife 2021, 10, e63225.

Yoon, A.; Zhen, J.; Guo, Z. Segmental Structural Dynamics in Aβ42 Globulomers. Biochem Biophys Res Commun 2021, 545, 119–124.

Hancock, G. V.; Liu, W.; Peretz, L.; Chen, D.; Gell, J. J.; Collier, A. J.; Zamudio, J. R.; Plath, K.; Clark, A. T. Divergent Roles for KLF4 and TFCP2L1 in Naive Ground State Pluripotency and Human Primordial Germ Cell Development. Stem Cell Res 2021, 55, 102493.

Wang, J. C.; Ramaswami, G.; Geschwind, D. H. Gene Co-Expression Network Analysis in Human Spinal Cord Highlights Mechanisms Underlying Amyotrophic Lateral Sclerosis Susceptibility. Sci Rep 2021, 11 (1), 5748.

Zhang, Z.; Park, J. W.; Ahn, I. S.; Diamante, G.; Sivakumar, N.; Arneson, D.; Yang, X.; van Veen, J. E.; Correa, S. M. Estrogen Receptor Alpha in the Brain Mediates Tamoxifen-Induced Changes in Physiology in Mice. Elife 2021, 10, e63333.

Liu, X.; Flores, A. A.; Situ, L.; Gu, W.; Ding, H.; Christofk, H. R.; Lowry, W. E.; Jung, M. E. Development of Novel Mitochondrial Pyruvate Carrier Inhibitors to Treat Hair Loss. J Med Chem 2021, 64 (4), 2046–2063.

Moridzadeh, R. S.; Sanaiha, Y.; Madrigal, J.; Antonios, J.; Benharash, P.; Baril, D. T. Nationwide Comparison of the Medical Complexity of Patients by Surgical Specialty. J Vasc Surg 2021, 73 (2), 683-688.e2.

Zhao, Y.; Iyer, S.; Tavanaei, M.; Nguyen, N. T.; Lin, A.; Nguyen, T. P. Proarrhythmic Electrical Remodeling by Noncardiomyocytes at Interfaces With Cardiomyocytes Under Oxidative Stress. Front Physiol 2020, 11, 622613.

Guo, J.; Sosa, E.; Chitiashvili, T.; Nie, X.; Rojas, E. J.; Oliver, E.; DonorConnect; Plath, K.; Hotaling, J. M.; Stukenborg, J.-B.; Clark, A. T.; Cairns, B. R. Single-Cell Analysis of the Developing Human Testis Reveals Somatic Niche Cell Specification and Fetal Germline Stem Cell Establishment. Cell Stem Cell 2021, 28 (4), 764-778.e4.

Yu, T. C.; Liu, W. L.; Brinck, M. S.; Davis, J. E.; Shek, J.; Bower, G.; Einav, T.; Insigne, K. D.; Phillips, R.; Kosuri, S.; Urtecho, G. Multiplexed Characterization of Rationally Designed Promoter Architectures Deconstructs Combinatorial Logic for IPTG-Inducible Systems. Nat Commun 2021, 12 (1), 325.

Prakash, R.; Thareja, N. S.; Carmichael, T. S.; Barnhill, R. L.; Lugassy, C.; Bentolila, L. A. Visualizing Pericyte Mimicry of Angiotropic Melanoma by Direct Labeling of the Angioarchitecture. Methods Mol Biol 2021, 2235, 1–12.

Sinha, S. K.; Miikeda, A.; Fouladian, Z.; Mehrabian, M.; Edillor, C.; Shih, D.; Zhou, Z.; Paul, M. K.; Charugundla, S.; Davis, R. C.; Rajavashisth, T. B.; Lusis, A. J. Local M-CSF (Macrophage Colony-Stimulating Factor) Expression Regulates Macrophage Proliferation and Apoptosis in Atherosclerosis. Arterioscler Thromb Vasc Biol 2021, 41 (1), 220–233.

Khachatryan, T.; Doctorian, T.; Stoletniy, L.; Abdipour, A.; Hilliard, A.; Abramov, D.; Zadeii, G.; Chung, J. H.; Krystal, C.; Abudayyeh, I. Comparison of Outcomes in Patients Undergoing Renal Transplantation With Impaired vs Normal Left Ventricular Ejection Fraction. Transplant Proc 2021, 53 (6), 1880–1886.

 

2020

Patananan, A. N.; Sercel, A. J.; Wu, T.-H.; Ahsan, F. M.; Torres, A.; Kennedy, S. A. L.; Vandiver, A.; Collier, A. J.; Mehrabi, A.; Van Lew, J.; Zakin, L.; Rodriguez, N.; Sixto, M.; Tadros, W.; Lazar, A.; Sieling, P. A.; Nguyen, T. L.; Dawson, E. R.; Braas, D.; Golovato, J.; Cisneros, L.; Vaske, C.; Plath, K.; Rabizadeh, S.; Niazi, K. R.; Chiou, P.-Y.; Teitell, M. A. Pressure-Driven Mitochondrial Transfer Pipeline Generates Mammalian Cells of Desired Genetic Combinations and Fates. Cell Rep 2020, 33 (13), 108562.

Jelinek, D.; Zhang, E. R.; Ambrus, A.; Haley, E.; Guinn, E.; Vo, A.; Le, P.; Kesaf, A. E.; Nguyen, J.; Guo, L.; Frederick, D.; Sun, Z.; Guo, N.; Sevier, P.; Bilotta, E.; Atai, K.; Voisin, L.; Coller, H. A. A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth. J Vis Exp 2020, No. 166.

Zyrianova, T.; Lopez, B.; Olcese, R.; Belperio, J.; Waters, C. M.; Wong, L.; Nguyen, V.; Talapaneni, S.; Schwingshackl, A. K2P2.1 (TREK-1) Potassium Channel Activation Protects against Hyperoxia-Induced Lung Injury. Sci Rep 2020, 10 (1), 22011.

Ghoshal, B.; Vong, B.; Picard, C. L.; Feng, S.; Tam, J. M.; Jacobsen, S. E. A Viral Guide RNA Delivery System for CRISPR-Based Transcriptional Activation and Heritable Targeted DNA Demethylation in Arabidopsis Thaliana. PLoS Genet 2020, 16 (12), e1008983.

Zhang, Z.; Reis, F. M. C. V.; He, Y.; Park, J. W.; DiVittorio, J. R.; Sivakumar, N.; van Veen, J. E.; Maesta-Pereira, S.; Shum, M.; Nichols, I.; Massa, M. G.; Anderson, S.; Paul, K.; Liesa, M.; Ajijola, O. A.; Xu, Y.; Adhikari, A.; Correa, S. M. Estrogen-Sensitive Medial Preoptic Area Neurons Coordinate Torpor in Mice. Nat Commun 2020, 11 (1), 6378.

Colozza, G.; Jami-Alahmadi, Y.; Dsouza, A.; Tejeda-Muñoz, N.; Albrecht, L. V.; Sosa, E. A.; Wohlschlegel, J. A.; De Robertis, E. M. Wnt-Inducible Lrp6-APEX2 Interacting Proteins Identify ESCRT Machinery and Trk-Fused Gene as Components of the Wnt Signaling Pathway. Sci Rep 2020, 10 (1), 21555. https://doi.org/10.1038/s41598-020-78019-5.

Sanaiha, Y.; Ziaeian, B.; Antonios, J. W.; Kavianpour, B.; Anousheh, R.; Benharash, P. Intraaortic Balloon Pump vs Peripheral Ventricular Assist Device Use in the United States. Ann Thorac Surg 2020, 110 (6), 1997–2005.

Chitiashvili, T.; Dror, I.; Kim, R.; Hsu, F.-M.; Chaudhari, R.; Pandolfi, E.; Chen, D.; Liebscher, S.; Schenke-Layland, K.; Plath, K.; Clark, A. Female Human Primordial Germ Cells Display X-Chromosome Dosage Compensation despite the Absence of X-Inactivation. Nat Cell Biol 2020, 22 (12), 1436–1446.

Leung, K. L.; Sanchita, S.; Pham, C. T.; Davis, B. A.; Okhovat, M.; Ding, X.; Dumesic, P.; Grogan, T. R.; Williams, K. J.; Morselli, M.; Ma, F.; Carbone, L.; Li, X.; Pellegrini, M.; Dumesic, D. A.; Chazenbalk, G. D. Dynamic Changes in Chromatin Accessibility, Altered Adipogenic Gene Expression, and Total versus de Novo Fatty Acid Synthesis in Subcutaneous Adipose Stem Cells of Normal-Weight Polycystic Ovary Syndrome (PCOS) Women during Adipogenesis: Evidence of Cellular Programming. Clin Epigenetics 2020, 12 (1), 181.

Brar, G.; Farhat, N. A.; Sukhina, A.; Lam, A. K.; Kim, Y. H.; Hsu, T.; Tong, L.; Lin, W. W.; Ware, C. F.; Blackman, M. A.; Sun, R.; Wu, T.-T. Deletion of Immune Evasion Genes Provides an Effective Vaccine Design for Tumor-Associated Herpesviruses. NPJ Vaccines 2020, 5 (1), 102.

de Barros, S. C.; Suterwala, B. T.; He, C.; Ge, S.; Chick, B.; Blumberg, G. K.; Kim, K.; Klein, S.; Zhu, Y.; Wang, X.; Casero, D.; Crooks, G. M. Pleiotropic Roles of VEGF in the Microenvironment of the Developing Thymus. J Immunol 2020, 205 (9), 2423–2436.

Zhao, G.; Kim, E. W.; Jiang, J.; Bhoot, C.; Charles, K. R.; Baek, J.; Mohan, S.; Adams, J. S.; Tetradis, S.; Lyons, K. M. CCN1/Cyr61 Is Required in Osteoblasts for Responsiveness to the Anabolic Activity of PTH. J Bone Miner Res 2020, 35 (11), 2289–2300.

Aguayo, E.; Antonios, J.; Sanaiha, Y.; Dobaria, V.; Kwon, O. J.; Sareh, S.; Benharash, P.; King, J. C. Readmission and Resource Use After Robotic-Assisted versus Open Pancreaticoduodenectomy: 2010-2017. J Surg Res 2020, 255, 517–524.

Aguayo, E.; Antonios, J.; Sanaiha, Y.; Dobaria, V.; Sareh, S.; Huynh, A.; Benharash, P.; King, J. C. National Trends in Readmission and Resource Utilization After Pancreatectomy in the United States. J Surg Res 2020, 255, 304–310.

Montel-Hagen, A.; Sun, V.; Casero, D.; Tsai, S.; Zampieri, A.; Jackson, N.; Li, S.; Lopez, S.; Zhu, Y.; Chick, B.; He, C.; de Barros, S. C.; Seet, C. S.; Crooks, G. M. In Vitro Recapitulation of Murine Thymopoiesis from Single Hematopoietic Stem Cells. Cell Rep 2020, 33 (4), 108320. https://doi.org/10.1016/j.celrep.2020.108320.

Hu, Y.; Zhong, J.; Xiao, Y.; Xing, Z.; Sheu, K.; Fan, S.; An, Q.; Qiu, Y.; Zheng, Y.; Liu, X.; Fan, G.; Liu, Y. Single-Cell RNA Cap and Tail Sequencing (ScRCAT-Seq) Reveals Subtype-Specific Isoforms Differing in Transcript Demarcation. Nat Commun 2020, 11 (1), 5148.

Ramaswami, G.; Won, H.; Gandal, M. J.; Haney, J.; Wang, J. C.; Wong, C. C. Y.; Sun, W.; Prabhakar, S.; Mill, J.; Geschwind, D. H. Integrative Genomics Identifies a Convergent Molecular Subtype That Links Epigenomic with Transcriptomic Differences in Autism. Nat Commun 2020, 11 (1), 4873.

Welc, S. S.; Wehling-Henricks, M.; Antoun, J.; Ha, T. T.; Tous, I.; Tidball, J. G. Differential Effects of Myeloid Cell PPARδ and IL-10 in Regulating Macrophage Recruitment, Phenotype, and Regeneration Following Acute Muscle Injury. J Immunol 2020, 205 (6), 1664–1677.

Miao, Z.; Alvarez, M.; Ko, A.; Bhagat, Y.; Rahmani, E.; Jew, B.; Heinonen, S.; Muñoz-Hernandez, L. L.; Herrera-Hernandez, M.; Aguilar-Salinas, C.; Tusie-Luna, T.; Mohlke, K. L.; Laakso, M.; Pietiläinen, K. H.; Halperin, E.; Pajukanta, P. The Causal Effect of Obesity on Prediabetes and Insulin Resistance Reveals the Important Role of Adipose Tissue in Insulin Resistance. PLoS Genet 2020, 16 (9), e1009018.

Kingsbury, L.; Huang, S.; Raam, T.; Ye, L. S.; Wei, D.; Hu, R. K.; Ye, L.; Hong, W. Cortical Representations of Conspecific Sex Shape Social Behavior. Neuron 2020, 107 (5), 941-953.e7.

Aros, C. J.; Vijayaraj, P.; Pantoja, C. J.; Bisht, B.; Meneses, L. K.; Sandlin, J. M.; Tse, J. A.; Chen, M. W.; Purkayastha, A.; Shia, D. W.; Sucre, J. M. S.; Rickabaugh, T. M.; Vladar, E. K.; Paul, M. K.; Gomperts, B. N. Distinct Spatiotemporally Dynamic Wnt-Secreting Niches Regulate Proximal Airway Regeneration and Aging. Cell Stem Cell 2020, 27 (3), 413-429.e4.

Yvone, G. M.; Chavez-Martinez, C. L.; Nguyen, A. R.; Wang, D. J.; Phelps, P. E. Reelin Dorsal Horn Neurons Co-Express Lmx1b and Are Mispositioned in Disabled-1 Mutant Mice. Eur J Neurosci 2020, 52 (5), 3322–3338. https://doi.org/10.1111/ejn.14847.

Dawson, E. R.; Patananan, A. N.; Sercel, A. J.; Teitell, M. A. Stable Retention of Chloramphenicol-Resistant MtDNA to Rescue Metabolically Impaired Cells. Sci Rep 2020, 10 (1), 14328.

Park, G.; Xue, C.; Wang, H.; Guo, Z. Distinguishing the Effect on the Rate and Yield of Aβ42 Aggregation by Green Tea Polyphenol EGCG. ACS Omega 2020, 5 (34), 21497–21505.

Gholkar, A. A.; Schmollinger, S.; Velasquez, E. F.; Lo, Y.-C.; Cohn, W.; Capri, J.; Dharmarajan, H.; Deardorff, W. J.; Gao, L. W.; Abdusamad, M.; Whitelegge, J. P.; Torres, J. Z. Regulation of Iron Homeostasis through Parkin-Mediated Lactoferrin Ubiquitylation. Biochemistry 2020, 59 (32), 2916–2921. https://doi.org/10.1021/acs.biochem.0c00504.

Jiang, M.; Paniagua, A. E.; Volland, S.; Wang, H.; Balaji, A.; Li, D. G.; Lopes, V. S.; Burgess, B. L.; Williams, D. S. Microtubule Motor Transport in the Delivery of Melanosomes to the Actin-Rich Apical Domain of the Retinal Pigment Epithelium. J Cell Sci 2020, 133 (15), jcs242214.

Rudasill, S. E.; Morales, R. R.; Sanaiha, Y.; Sareh, S.; Antonios, J. W.; Khoury, H.; Mardock, A. L.; Benharash, P. Predicting Morbidity and Mortality in Laparoscopic Cholecystectomy: Preoperative Serum Albumin Still Matters. Am J Surg 2020, 220 (2), 432–437.

Lau, Y. C. C.; Ding, J. A.; Simental, A.; Mirzoyan, H.; Lee, W.; Diamante, G.; Cely, I.; Tran, M.; Morselli, M.; Dang, J.; Kaczor-Urbanowicz, K. E.; Sayre, J.; Stiles, L.; Yang, X.; Pellegrini, M.; Fiala, M. Omega-3 Fatty Acids Increase OXPHOS Energy for Immune Therapy of Alzheimer Disease Patients. FASEB J 2020, 34 (8), 9982–9994.

Albrecht, L. V.; Tejeda-Muñoz, N.; Bui, M. H.; Cicchetto, A. C.; Di Biagio, D.; Colozza, G.; Schmid, E.; Piccolo, S.; Christofk, H. R.; De Robertis, E. M. GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery. Cell Rep 2020, 32 (4), 107973.

Fang, T.; Zhang, Y.; Chang, V. Y.; Roos, M.; Termini, C. M.; Signaevskaia, L.; Quarmyne, M.; Lin, P. K.; Pang, A.; Kan, J.; Yan, X.; Javier, A.; Pohl, K.; Zhao, L.; Scott, P.; Himburg, H. A.; Chute, J. P. Epidermal Growth Factor Receptor-Dependent DNA Repair Promotes Murine and Human Hematopoietic Regeneration. Blood 2020, 136 (4), 441–454. https://doi.org/10.1182/blood.2020005895.

Xi, H.; Langerman, J.; Sabri, S.; Chien, P.; Young, C. S.; Younesi, S.; Hicks, M.; Gonzalez, K.; Fujiwara, W.; Marzi, J.; Liebscher, S.; Spencer, M.; Van Handel, B.; Evseenko, D.; Schenke-Layland, K.; Plath, K.; Pyle, A. D. A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. Cell Stem Cell 2020, 27 (1), 158-176.e10.

Young, P. A.; Gaut, D.; Kimaiyo, D. K.; Grotts, J.; Romero, T.; Chute, J.; Schiller, G.; de Vos, S.; Eradat, H. A.; Timmerman, J. Durable Survival Outcomes in Primary and Secondary Central Nervous System Lymphoma After High-Dose Chemotherapy and Autologous Stem Cell Transplantation Using a Thiotepa, Busulfan, and Cyclophosphamide Conditioning Regimen. Clin Lymphoma Myeloma Leuk 2020, 20 (7), 468–479.

Dumesic, D. A.; Abbott, D. H.; Sanchita, S.; Chazenbalk, G. D. Endocrine-Metabolic Dysfunction in Polycystic Ovary Syndrome: An Evolutionary Perspective. Curr Opin Endocr Metab Res 2020, 12, 41–48.

Riggan, L.; Hildreth, A. D.; Rolot, M.; Wong, Y.-Y.; Satyadi, W.; Sun, R.; Huerta, C.; O’Sullivan, T. E. CRISPR-Cas9 Ribonucleoprotein-Mediated Genomic Editing in Mature Primary Innate Immune Cells. Cell Rep 2020, 31 (7), 107651.

Tsang, J. E.; Urner, L. M.; Kim, G.; Chow, K.; Baufeld, L.; Faull, K.; Cloughesy, T. F.; Clark, P. M.; Jung, M. E.; Nathanson, D. A. Development of a Potent Brain-Penetrant EGFR Tyrosine Kinase Inhibitor against Malignant Brain Tumors. ACS Med Chem Lett 2020, 11 (10), 1799–1809.

Suh, J. S.; Lee, S. H.; Fouladian, Z.; Lee, J. Y.; Kim, T.; Kang, M. K.; Lusis, A. J.; Boström, K. I.; Kim, R. H.; Park, N.-H. Rosuvastatin Prevents the Exacerbation of Atherosclerosis in Ligature-Induced Periodontal Disease Mouse Model. Sci Rep 2020, 10 (1), 6383.

Ge, P.; Scholl, D.; Prokhorov, N. S.; Avaylon, J.; Shneider, M. M.; Browning, C.; Buth, S. A.; Plattner, M.; Chakraborty, U.; Ding, K.; Leiman, P. G.; Miller, J. F.; Zhou, Z. H. Action of a Minimal Contractile Bactericidal Nanomachine. Nature 2020, 580 (7805), 658–662.

van Veen, J. E.; Kammel, L. G.; Bunda, P. C.; Shum, M.; Reid, M. S.; Massa, M. G.; Arneson, D.; Park, J. W.; Zhang, Z.; Joseph, A. M.; Hrncir, H.; Liesa, M.; Arnold, A. P.; Yang, X.; Correa, S. M. Hypothalamic Estrogen Receptor Alpha Establishes a Sexually Dimorphic Regulatory Node of Energy Expenditure. Nat Metab 2020, 2 (4), 351–363. https://doi.org/10.1038/s42255-020-0189-6.

Wang, H.; Duo, L.; Hsu, F.; Xue, C.; Lee, Y. K.; Guo, Z. Polymorphic Aβ42 Fibrils Adopt Similar Secondary Structure but Differ in Cross-Strand Side Chain Stacking Interactions within the Same β-Sheet. Sci Rep 2020, 10 (1), 5720. https://doi.org/10.1038/s41598-020-62181-x.

Gell, J. J.; Liu, W.; Sosa, E.; Chialastri, A.; Hancock, G.; Tao, Y.; Wamaitha, S. E.; Bower, G.; Dey, S. S.; Clark, A. T. An Extended Culture System That Supports Human Primordial Germ Cell-like Cell Survival and Initiation of DNA Methylation Erasure. Stem Cell Reports 2020, 14 (3), 433–446.

Aros, C. J.; Paul, M. K.; Pantoja, C. J.; Bisht, B.; Meneses, L. K.; Vijayaraj, P.; Sandlin, J. M.; France, B.; Tse, J. A.; Chen, M. W.; Shia, D. W.; Rickabaugh, T. M.; Damoiseaux, R.; Gomperts, B. N. High-Throughput Drug Screening Identifies a Potent Wnt Inhibitor That Promotes Airway Basal Stem Cell Homeostasis. Cell Rep 2020, 30 (7), 2055-2064.e5.

Himburg, H. A.; Roos, M.; Fang, T.; Zhang, Y.; Termini, C. M.; Schlussel, L.; Kim, M.; Pang, A.; Kan, J.; Zhao, L.; Suh, H.; Sasine, J. P.; Sapparapu, G.; Bowers, P. M.; Schiller, G.; Chute, J. P. Chronic Myeloid Leukemia Stem Cells Require Cell-Autonomous Pleiotrophin Signaling. J Clin Invest 2020, 130 (1), 315–328.

Ji, M. S.; Eldred, B. S. C.; Liu, R.; Pianka, S. T.; Molaie, D.; Kevan, B.; Pan, S.; Lai, T. J.; Nguyen, N. T.; Chow, F. E.; Yong, W. H.; Cox, C. D.; Reeh, D. N.; Li, T.; Liau, L. M.; Nghiemphu, P. L.; Cloughesy, T. F.; Li, G.; Lai, A. Targeted Next-Generation Sequencing of 565 Neuro-Oncology Patients at UCLA: A Single-Institution Experience. Neurooncol Adv 2020, 2 (1), vdaa009.

 

2019

Sun, X.; Thörn Pérez, C.; Halemani D, N.; Shao, X. M.; Greenwood, M.; Heath, S.; Feldman, J. L.; Kam, K. Opioids Modulate an Emergent Rhythmogenic Process to Depress Breathing. Elife 2019, 8, e50613.

Vijayaraj, P.; Minasyan, A.; Durra, A.; Karumbayaram, S.; Mehrabi, M.; Aros, C. J.; Ahadome, S. D.; Shia, D. W.; Chung, K.; Sandlin, J. M.; Darmawan, K. F.; Bhatt, K. V.; Manze, C. C.; Paul, M. K.; Wilkinson, D. C.; Yan, W.; Clark, A. T.; Rickabaugh, T. M.; Wallace, W. D.; Graeber, T. G.; Damoiseaux, R.; Gomperts, B. N. Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-Fibrotic Small Molecule. Cell Rep 2019, 29 (11), 3488-3505.e9.

Crowell, P. D.; Giafaglione, J. M.; Hashimoto, T.; Diaz, J. A.; Goldstein, A. S. Evaluating the Differentiation Capacity of Mouse Prostate Epithelial Cells Using Organoid Culture. J Vis Exp 2019, No. 153. https://doi.org/10.3791/60223.

Frendo, M. E.; da Silva, A.; Phan, K. D.; Riche, S.; Butler, S. J. The Cofilin/Limk1 Pathway Controls the Growth Rate of Both Developing and Regenerating Motor Axons. J Neurosci 2019, 39 (47), 9316–9327.

Zhang, W.; Kassels, A. C.; Barrington, A.; Khan, S.; Tomatsu, S.; Alkadi, T.; Aldave, A. Macular Corneal Dystrophy with Isolated Peripheral Descemet Membrane Deposits. Am J Ophthalmol Case Rep 2019, 16, 100571.

Chun, R. F.; Shieh, A.; Gottlieb, C.; Yacoubian, V.; Wang, J.; Hewison, M.; Adams, J. S. Vitamin D Binding Protein and the Biological Activity of Vitamin D. Front Endocrinol (Lausanne) 2019, 10, 718.

Khalid, M. A.; Ray, A.; Cohen, S.; Tassieri, M.; Demčenko, A.; Tseng, D.; Reboud, J.; Ozcan, A.; Cooper, J. M. Computational Image Analysis of Guided Acoustic Waves Enables Rheological Assessment of Sub-Nanoliter Volumes. ACS Nano 2019, 13 (10), 11062–11069.

Barshop, W. D.; Kim, H. J.; Fan, X.; Sha, J.; Rayatpisheh, S.; Wohlschlegel, J. A. Chemical Derivatization of Affinity Matrices Provides Protection from Tryptic Proteolysis. J Proteome Res 2019, 18 (10), 3586–3596.

Zhu, Y.; Smith, D. J.; Zhou, Y.; Li, Y.-R.; Yu, J.; Lee, D.; Wang, Y.-C.; Di Biase, S.; Wang, X.; Hardoy, C.; Ku, J.; Tsao, T.; Lin, L. J.; Pham, A. T.; Moon, H.; McLaughlin, J.; Cheng, D.; Hollis, R. P.; Campo-Fernandez, B.; Urbinati, F.; Wei, L.; Pang, L.; Rezek, V.; Berent-Maoz, B.; Macabali, M. H.; Gjertson, D.; Wang, X.; Galic, Z.; Kitchen, S. G.; An, D. S.; Hu-Lieskovan, S.; Kaplan-Lefko, P. J.; De Oliveira, S. N.; Seet, C. S.; Larson, S. M.; Forman, S. J.; Heath, J. R.; Zack, J. A.; Crooks, G. M.; Radu, C. G.; Ribas, A.; Kohn, D. B.; Witte, O. N.; Yang, L. Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. Cell Stem Cell 2019, 25 (4), 542-557.e9.

Rudasill, S. E.; Sanaiha, Y.; Mardock, A. L.; Khoury, H.; Xing, H.; Antonios, J. W.; McKinnell, J. A.; Benharash, P. Clinical Outcomes of Infective Endocarditis in Injection Drug Users. J Am Coll Cardiol 2019, 73 (5), 559–570.

Man, T.; Zhu, X.; Chow, Y. T.; Dawson, E. R.; Wen, X.; Patananan, A. N.; Liu, T. L.; Zhao, C.; Wu, C.; Hong, J. S.; Chung, P.-S.; Clemens, D. L.; Lee, B.-Y.; Weiss, P. S.; Teitell, M. A.; Chiou, P.-Y. Intracellular Photothermal Delivery for Suspension Cells Using Sharp Nanoscale Tips in Microwells. ACS Nano 2019, 13 (9), 10835–10844.

Pandolfi, E. C.; Rojas, E. J.; Sosa, E.; Gell, J. J.; Hunt, T. J.; Goldsmith, S.; Fan, Y.; Silber, S. J.; Clark, A. T. Generation of Three Human Induced Pluripotent Stem Cell Sublines (MZT04D, MZT04J, MZT04C) for Reproductive Science Research. Stem Cell Res 2019, 40, 101576.

Fox, J. J.; Navarro, H. I.; Hashimoto, T.; Garcia, A. J.; Goldstein, A. S. Mass Cytometry Reveals Species-Specific Differences and a New Level of Complexity for Immune Cells in the Prostate. Am J Clin Exp Urol 2019, 7 (4), 281–296.

Benhammou, J. N.; Ko, A.; Alvarez, M.; Kaikkonen, M. U.; Rankin, C.; Garske, K. M.; Padua, D.; Bhagat, Y.; Kaminska, D.; Kärjä, V.; Pihlajamäki, J.; Pisegna, J. R.; Pajukanta, P. Novel Lipid Long Intervening Noncoding RNA, Oligodendrocyte Maturation-Associated Long Intergenic Noncoding RNA, Regulates the Liver Steatosis Gene Stearoyl-Coenzyme A Desaturase As an Enhancer RNA. Hepatol Commun 2019, 3 (10), 1356–1372. https://doi.org/10.1002/hep4.1413.

Warmack, R. A.; Shawa, H.; Liu, K.; Lopez, K.; Loo, J. A.; Horwitz, J.; Clarke, S. G. The L-Isoaspartate Modification within Protein Fragments in the Aging Lens Can Promote Protein Aggregation. J Biol Chem 2019, 294 (32), 12203–12219.

Crowell, P. D.; Fox, J. J.; Hashimoto, T.; Diaz, J. A.; Navarro, H. I.; Henry, G. H.; Feldmar, B. A.; Lowe, M. G.; Garcia, A. J.; Wu, Y. E.; Sajed, D. P.; Strand, D. W.; Goldstein, A. S. Expansion of Luminal Progenitor Cells in the Aging Mouse and Human Prostate. Cell Rep 2019, 28 (6), 1499-1510.e6.

Wang, W.; Chun, H.; Baek, J.; Sadik, J. E.; Shirazyan, A.; Razavi, P.; Lopez, N.; Lyons, K. M. The TGFβ Type I Receptor TGFβRI Functions as an Inhibitor of BMP Signaling in Cartilage. Proc Natl Acad Sci U S A 2019, 116 (31), 15570–15579.

Xue, C.; Tran, J.; Wang, H.; Park, G.; Hsu, F.; Guo, Z. Aβ42 Fibril Formation from Predominantly Oligomeric Samples Suggests a Link between Oligomer Heterogeneity and Fibril Polymorphism. R Soc Open Sci 2019, 6 (7), 190179.

Balanis, N. G.; Sheu, K. M.; Esedebe, F. N.; Patel, S. J.; Smith, B. A.; Park, J. W.; Alhani, S.; Gomperts, B. N.; Huang, J.; Witte, O. N.; Graeber, T. G. Pan-Cancer Convergence to a Small-Cell Neuroendocrine Phenotype That Shares Susceptibilities with Hematological Malignancies. Cancer Cell 2019, 36 (1), 17-34.e7.

Wang, X.; Yvone, G. M.; Cilluffo, M.; Kim, A. S.; Basbaum, A. I.; Phelps, P. E. Mispositioned Neurokinin-1 Receptor-Expressing Neurons Underlie Heat Hyperalgesia in Disabled-1 Mutant Mice. eNeuro 2019, 6 (3), ENEURO.0131-19.2019.

Cheng, K. Y.; Colbath, R. A.; Frye, M. A. Olfactory and Neuromodulatory Signals Reverse Visual Object Avoidance to Approach in Drosophila. Curr Biol 2019, 29 (12), 2058-2065.e2.

Frausto, R. F.; Chung, D. D.; Boere, P. M.; Swamy, V. S.; Duong, H. N. V.; Kao, L.; Azimov, R.; Zhang, W.; Carrigan, L.; Wong, D.; Morselli, M.; Zakharevich, M.; Hanser, E. M.; Kassels, A. C.; Kurtz, I.; Pellegrini, M.; Aldave, A. J. ZEB1 Insufficiency Causes Corneal Endothelial Cell State Transition and Altered Cellular Processing. PLoS One 2019, 14 (6), e0218279.

Hu, X.; Matsumoto, K.; Jung, R. S.; Weston, T. A.; Heizer, P. J.; He, C.; Sandoval, N. P.; Allan, C. M.; Tu, Y.; Vinters, H. V.; Liau, L. M.; Ellison, R. M.; Morales, J. E.; Baufeld, L. J.; Bayley, N. A.; He, L.; Betsholtz, C.; Beigneux, A. P.; Nathanson, D. A.; Gerhardt, H.; Young, S. G.; Fong, L. G.; Jiang, H. GPIHBP1 Expression in Gliomas Promotes Utilization of Lipoprotein-Derived Nutrients. Elife 2019, 8, e47178.

Dumesic, D. A.; Phan, J. D.; Leung, K. L.; Grogan, T. R.; Ding, X.; Li, X.; Hoyos, L. R.; Abbott, D. H.; Chazenbalk, G. D. Adipose Insulin Resistance in Normal-Weight Women With Polycystic Ovary Syndrome. J Clin Endocrinol Metab 2019, 104 (6), 2171–2183. https://doi.org/10.1210/jc.2018-02086.

Garske, K. M.; Pan, D. Z.; Miao, Z.; Bhagat, Y. V.; Comenho, C.; Robles, C. R.; Benhammou, J. N.; Alvarez, M.; Ko, A.; Ye, C. J.; Pisegna, J. R.; Mohlke, K. L.; Sinsheimer, J. S.; Laakso, M.; Pajukanta, P. Reverse Gene-Environment Interaction Approach to Identify Variants Influencing Body-Mass Index in Humans. Nat Metab 2019, 1 (6), 630–642.

Lazaro, M. T.; Taxidis, J.; Shuman, T.; Bachmutsky, I.; Ikrar, T.; Santos, R.; Marcello, G. M.; Mylavarapu, A.; Chandra, S.; Foreman, A.; Goli, R.; Tran, D.; Sharma, N.; Azhdam, M.; Dong, H.; Choe, K. Y.; Peñagarikano, O.; Masmanidis, S. C.; Rácz, B.; Xu, X.; Geschwind, D. H.; Golshani, P. Reduced Prefrontal Synaptic Connectivity and Disturbed Oscillatory Population Dynamics in the CNTNAP2 Model of Autism. Cell Rep 2019, 27 (9), 2567-2578.e6. https://doi.org/10.1016/j.celrep.2019.05.006.

Octeau, J. C.; Gangwani, M. R.; Allam, S. L.; Tran, D.; Huang, S.; Hoang-Trong, T. M.; Golshani, P.; Rumbell, T. H.; Kozloski, J. R.; Khakh, B. S. Transient, Consequential Increases in Extracellular Potassium Ions Accompany Channelrhodopsin2 Excitation. Cell Rep 2019, 27 (8), 2249-2261.e7.

Tejeda-Muñoz, N.; Albrecht, L. V.; Bui, M. H.; De Robertis, E. M. Wnt Canonical Pathway Activates Macropinocytosis and Lysosomal Degradation of Extracellular Proteins. Proc Natl Acad Sci U S A 2019, 116 (21), 10402–10411.

Xu, S.; Zhou, T.; Doh, H. M.; Trinh, K. R.; Catapang, A.; Lee, J. T.; Braas, D.; Bayley, N. A.; Yamada, R. E.; Vasuthasawat, A.; Sasine, J. P.; Timmerman, J. M.; Larson, S. M.; Kim, Y.; MacLeod, A. R.; Morrison, S. L.; Herschman, H. R. An HK2 Antisense Oligonucleotide Induces Synthetic Lethality in HK1-HK2+ Multiple Myeloma. Cancer Res 2019, 79 (10), 2748–2760.

Day, N. F.; Hobbs, T. G.; Heston, J. B.; White, S. A. Beyond Critical Period Learning: Striatal FoxP2 Affects the Active Maintenance of Learned Vocalizations in Adulthood. eNeuro 2019, 6 (2), ENEURO.0071-19.2019.

Prakash, R.; Izraely, S.; Thareja, N. S.; Lee, R. H.; Rappaport, M.; Kawaguchi, R.; Sagi-Assif, O.; Ben-Menachem, S.; Meshel, T.; Machnicki, M.; Ohe, S.; Hoon, D. S.; Coppola, G.; Witz, I. P.; Carmichael, S. T. Regeneration Enhances Metastasis: A Novel Role for Neurovascular Signaling in Promoting Melanoma Brain Metastasis. Front Neurosci 2019, 13, 297.

Barshop, W. D.; Rayatpisheh, S.; Kim, H. J.; Wohlschlegel, J. A. Sequential Windowed Acquisition of Reporter Masses for Quantitation-First Proteomics. J Proteome Res 2019, 18 (4), 1893–1901.

Elliott, I. A.; Dann, A. M.; Xu, S.; Kim, S. S.; Abt, E. R.; Kim, W.; Poddar, S.; Moore, A.; Zhou, L.; Williams, J. L.; Capri, J. R.; Ghukasyan, R.; Matsumura, C.; Tucker, D. A.; Armstrong, W. R.; Cabebe, A. E.; Wu, N.; Li, L.; Le, T. M.; Radu, C. G.; Donahue, T. R. Lysosome Inhibition Sensitizes Pancreatic Cancer to Replication Stress by Aspartate Depletion. Proc Natl Acad Sci U S A 2019, 116 (14), 6842–6847.

Flores, A.; Sandoval-Gonzalez, S.; Takahashi, R.; Krall, A.; Sathe, L.; Wei, L.; Radu, C.; Joly, J. H.; Graham, N. A.; Christofk, H. R.; Lowry, W. E. Increased Lactate Dehydrogenase Activity Is Dispensable in Squamous Carcinoma Cells of Origin. Nat Commun 2019, 10 (1), 91.

Urtecho, G.; Tripp, A. D.; Insigne, K. D.; Kim, H.; Kosuri, S. Systematic Dissection of Sequence Elements Controlling Σ70 Promoters Using a Genomically Encoded Multiplexed Reporter Assay in Escherichia Coli. Biochemistry 2019, 58 (11), 1539–1551.

Davidson, T. B.; Lee, A.; Hsu, M.; Sedighim, S.; Orpilla, J.; Treger, J.; Mastall, M.; Roesch, S.; Rapp, C.; Galvez, M.; Mochizuki, A.; Antonios, J.; Garcia, A.; Kotecha, N.; Bayless, N.; Nathanson, D.; Wang, A.; Everson, R.; Yong, W. H.; Cloughesy, T. F.; Liau, L. M.; Herold-Mende, C.; Prins, R. M. Expression of PD-1 by T Cells in Malignant Glioma Patients Reflects Exhaustion and Activation. Clin Cancer Res 2019, 25 (6), 1913–1922. https://doi.org/10.1158/1078-0432.CCR-18-1176.

Jiang, N.; Rasmussen, J. P.; Clanton, J. A.; Rosenberg, M. F.; Luedke, K. P.; Cronan, M. R.; Parker, E. D.; Kim, H.-J.; Vaughan, J. C.; Sagasti, A.; Parrish, J. Z. A Conserved Morphogenetic Mechanism for Epidermal Ensheathment of Nociceptive Sensory Neurites. Elife 2019, 8, e42455. https://doi.org/10.7554/eLife.42455.

Shigeta, A.; Huang, V.; Zuo, J.; Besada, R.; Nakashima, Y.; Lu, Y.; Ding, Y.; Pellegrini, M.; Kulkarni, R. P.; Hsiai, T.; Deb, A.; Zhou, B.; Nakano, H.; Nakano, A. Endocardially Derived Macrophages Are Essential for Valvular Remodeling. Dev Cell 2019, 48 (5), 617-630.e3.

Montel-Hagen, A.; Seet, C. S.; Li, S.; Chick, B.; Zhu, Y.; Chang, P.; Tsai, S.; Sun, V.; Lopez, S.; Chen, H.-C.; He, C.; Chin, C. J.; Casero, D.; Crooks, G. M. Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells. Cell Stem Cell 2019, 24 (3), 376-389.e8.

Wu, Y.; Luo, Y.; Chaudhari, G.; Rivenson, Y.; Calis, A.; de Haan, K.; Ozcan, A. Bright-Field Holography: Cross-Modality Deep Learning Enables Snapshot 3D Imaging with Bright-Field Contrast Using a Single Hologram. Light Sci Appl 2019, 8, 25.

Lee, H. N.; Bosompra, O. A.; Coller, H. A. RECK Isoforms Differentially Regulate Fibroblast Migration by Modulating Tubulin Post-Translational Modifications. Biochem Biophys Res Commun 2019, 510 (2), 211–218.

Cloughesy, T. F.; Mochizuki, A. Y.; Orpilla, J. R.; Hugo, W.; Lee, A. H.; Davidson, T. B.; Wang, A. C.; Ellingson, B. M.; Rytlewski, J. A.; Sanders, C. M.; Kawaguchi, E. S.; Du, L.; Li, G.; Yong, W. H.; Gaffey, S. C.; Cohen, A. L.; Mellinghoff, I. K.; Lee, E. Q.; Reardon, D. A.; O’Brien, B. J.; Butowski, N. A.; Nghiemphu, P. L.; Clarke, J. L.; Arrillaga-Romany, I. C.; Colman, H.; Kaley, T. J.; de Groot, J. F.; Liau, L. M.; Wen, P. Y.; Prins, R. M. Neoadjuvant Anti-PD-1 Immunotherapy Promotes a Survival Benefit with Intratumoral and Systemic Immune Responses in Recurrent Glioblastoma. Nat Med 2019, 25 (3), 477–486.

Joy, M. T.; Ben Assayag, E.; Shabashov-Stone, D.; Liraz-Zaltsman, S.; Mazzitelli, J.; Arenas, M.; Abduljawad, N.; Kliper, E.; Korczyn, A. D.; Thareja, N. S.; Kesner, E. L.; Zhou, M.; Huang, S.; Silva, T. K.; Katz, N.; Bornstein, N. M.; Silva, A. J.; Shohami, E.; Carmichael, S. T. CCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury. Cell 2019, 176 (5), 1143-1157.e13. https://doi.org/10.1016/j.cell.2019.01.044.

Albrecht, L. V.; Bui, M. H.; De Robertis, E. M. Canonical Wnt Is Inhibited by Targeting One-Carbon Metabolism through Methotrexate or Methionine Deprivation. Proc Natl Acad Sci U S A 2019, 116 (8), 2987–2995.

Rudasill, S. E.; DiPardo, B.; Sanaiha, Y.; Mardock, A. L.; Cale, M.; Antonios, J. W.; Khoury, H.; Benharash, P. International Normalized Ratio (INR) Is Comparable to MELD in Predicting Mortality after Cholecystectomy. Am Surg 2019, 85 (10), 1184–1188.

Sosa, E. A.; Moriyama, Y.; Ding, Y.; Tejeda-Muñoz, N.; Colozza, G.; De Robertis, E. M. Transcriptome Analysis of Regeneration during Xenopus Laevis Experimental Twinning. Int J Dev Biol 2019, 63 (6–7), 301–309. https://doi.org/10.1387/ijdb.190006ed.

Chen, D.; Liu, W.; Zimmerman, J.; Pastor, W. A.; Kim, R.; Hosohama, L.; Ho, J.; Aslanyan, M.; Gell, J. J.; Jacobsen, S. E.; Clark, A. T. The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation. Cell Rep 2018, 25 (13), 3591-3602.e5.

Xu, S.; Xiao, Q.; Cosmanescu, F.; Sergeeva, A. P.; Yoo, J.; Lin, Y.; Katsamba, P. S.; Ahlsen, G.; Kaufman, J.; Linaval, N. T.; Lee, P.-T.; Bellen, H. J.; Shapiro, L.; Honig, B.; Tan, L.; Zipursky, S. L. Interactions between the Ig-Superfamily Proteins DIP-α and Dpr6/10 Regulate Assembly of Neural Circuits. Neuron 2018, 100 (6), 1369-1384.e6.

Sosa, E.; Chen, D.; Rojas, E. J.; Hennebold, J. D.; Peters, K. A.; Wu, Z.; Lam, T. N.; Mitchell, J. M.; Sukhwani, M.; Tailor, R. C.; Meistrich, M. L.; Orwig, K. E.; Shetty, G.; Clark, A. T. Differentiation of Primate Primordial Germ Cell-like Cells Following Transplantation into the Adult Gonadal Niche. Nat Commun 2018, 9 (1), 5339.

(154) Criner, G. J.; Celli, B. R.; Brightling, C. E.; Agusti, A.; Papi, A.; Singh, D.; Sin, D. D.; Vogelmeier, C. F.; Sciurba, F. C.; Bafadhel, M.; Backer, V.; Kato, M.; Ramírez-Venegas, A.; Wei, Y.-F.; Bjermer, L.; Shih, V. H.; Jison, M.; O’Quinn, S.; Makulova, N.; Newbold, P.; Goldman, M.; Martin, U. J.; GALATHEA Study Investigators; TERRANOVA Study Investigators. Benralizumab for the Prevention of COPD Exacerbations. N Engl J Med 2019, 381 (11), 1023–1034. https://doi.org/10.1056/NEJMoa1905248.

(158) Calvanese, V.; Nguyen, A. T.; Bolan, T. J.; Vavilina, A.; Su, T.; Lee, L. K.; Wang, Y.; Lay, F. D.; Magnusson, M.; Crooks, G. M.; Kurdistani, S. K.; Mikkola, H. K. A. MLLT3 Governs Human Haematopoietic Stem-Cell Self-Renewal and Engraftment. Nature 2019, 576 (7786), 281–286. https://doi.org/10.1038/s41586-019-1790-2.

 

2018

Argus, J. P.; Wilks, M. Q.; Zhou, Q. D.; Hsieh, W. Y.; Khialeeva, E.; Hoi, X. P.; Bui, V.; Xu, S.; Yu, A. K.; Wang, E. S.; Herschman, H. R.; Williams, K. J.; Bensinger, S. J. Development and Application of FASA, a Model for Quantifying Fatty Acid Metabolism Using Stable Isotope Labeling. Cell Rep 2018, 25 (10), 2919-2934.e8.

Arcizet, F.; Mirpour, K.; Foster, D. J.; Bisley, J. W. Activity in LIP, But Not V4, Matches Performance When Attention Is Spread. Cereb Cortex 2018, 28 (12), 4195–4209.

Sahakyan, A.; Yang, Y.; Plath, K. The Role of Xist in X-Chromosome Dosage Compensation. Trends Cell Biol 2018, 28 (12), 999–1013.

Fisch, S. C.; Nikou, A. F.; Wright, E. A.; Phan, J. D.; Leung, K. L.; Grogan, T. R.; Abbott, D. H.; Chazenbalk, G. D.; Dumesic, D. A. Precocious Subcutaneous Abdominal Stem Cell Development to Adipocytes in Normal-Weight Women with Polycystic Ovary Syndrome. Fertil Steril 2018, 110 (7), 1367–1376.

Julien, D. P.; Chan, A. W.; Barrios, J.; Mathiaparanam, J.; Douglass, A.; Wolman, M. A.; Sagasti, A. Zebrafish Expression Reporters and Mutants Reveal That the IgSF Cell Adhesion Molecule Dscamb Is Required for Feeding and Survival. J Neurogenet 2018, 32 (4), 336–352.

Omoto, J. J.; Nguyen, B.-C. M.; Kandimalla, P.; Lovick, J. K.; Donlea, J. M.; Hartenstein, V. Neuronal Constituents and Putative Interactions Within the Drosophila Ellipsoid Body Neuropil. Front Neural Circuits 2018, 12, 103.

Metz, K. A.; Teng, X.; Coppens, I.; Lamb, H. M.; Wagner, B. E.; Rosenfeld, J. A.; Chen, X.; Zhang, Y.; Kim, H. J.; Meadow, M. E.; Wang, T. S.; Haberlandt, E. D.; Anderson, G. W.; Leshinsky-Silver, E.; Bi, W.; Markello, T. C.; Pratt, M.; Makhseed, N.; Garnica, A.; Danylchuk, N. R.; Burrow, T. A.; Jayakar, P.; McKnight, D.; Agadi, S.; Gbedawo, H.; Stanley, C.; Alber, M.; Prehl, I.; Peariso, K.; Ong, M. T.; Mordekar, S. R.; Parker, M. J.; Crooks, D.; Agrawal, P. B.; Berry, G. T.; Loddenkemper, T.; Yang, Y.; Maegawa, G. H. B.; Aouacheria, A.; Markle, J. G.; Wohlschlegel, J. A.; Hartman, A. L.; Hardwick, J. M. KCTD7 Deficiency Defines a Distinct Neurodegenerative Disorder with a Conserved Autophagy-Lysosome Defect. Ann Neurol 2018, 84 (5), 766–780.

Yu, I.; Nguyen, L.; Avaylon, J.; Wang, K.; Lai, M.; Zhou, Z. H. Building Atomic Models Based on near Atomic Resolution CryoEM Maps with Existing Tools. J Struct Biol 2018, 204 (2), 313–318.

He, C.; Hu, X.; Weston, T. A.; Jung, R. S.; Heizer, P.; Tu, Y.; Ellison, R.; Matsumoto, K.; Gerhardt, H.; Tontonoz, P.; Fong, L. G.; Young, S. G.; Jiang, H. NanoSIMS Imaging Reveals Unexpected Heterogeneity in Nutrient Uptake by Brown Adipocytes. Biochem Biophys Res Commun 2018, 504 (4), 899–902.

Zavala, K.; Gottlieb, C. A.; Teles, R. M.; Adams, J. S.; Hewison, M.; Modlin, R. L.; Liu, P. T. Intrinsic Activation of the Vitamin D Antimicrobial Pathway by M. Leprae Infection Is Inhibited by Type I IFN. PLoS Negl Trop Dis 2018, 12 (10), e0006815.

Sandhu, J.; Li, S.; Fairall, L.; Pfisterer, S. G.; Gurnett, J. E.; Xiao, X.; Weston, T. A.; Vashi, D.; Ferrari, A.; Orozco, J. L.; Hartman, C. L.; Strugatsky, D.; Lee, S. D.; He, C.; Hong, C.; Jiang, H.; Bentolila, L. A.; Gatta, A. T.; Levine, T. P.; Ferng, A.; Lee, R.; Ford, D. A.; Young, S. G.; Ikonen, E.; Schwabe, J. W. R.; Tontonoz, P. Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells. Cell 2018, 175 (2), 514-529.e20.

Goel, A.; Cantu, D. A.; Guilfoyle, J.; Chaudhari, G. R.; Newadkar, A.; Todisco, B.; de Alba, D.; Kourdougli, N.; Schmitt, L. M.; Pedapati, E.; Erickson, C. A.; Portera-Cailliau, C. Impaired Perceptual Learning in a Mouse Model of Fragile X Syndrome Is Mediated by Parvalbumin Neuron Dysfunction and Is Reversible. Nat Neurosci 2018, 21 (10), 1404–1411.

Ding, Y.; Colozza, G.; Sosa, E. A.; Moriyama, Y.; Rundle, S.; Salwinski, L.; De Robertis, E. M. Bighead Is a Wnt Antagonist Secreted by the Xenopus Spemann Organizer That Promotes Lrp6 Endocytosis. Proc Natl Acad Sci U S A 2018, 115 (39), E9135–E9144.

Smith, B. A.; Balanis, N. G.; Nanjundiah, A.; Sheu, K. M.; Tsai, B. L.; Zhang, Q.; Park, J. W.; Thompson, M.; Huang, J.; Witte, O. N.; Graeber, T. G. A Human Adult Stem Cell Signature Marks Aggressive Variants across Epithelial Cancers. Cell Rep 2018, 24 (12), 3353-3366.e5.

Park, S.; Ranjbarvaziri, S.; Lay, F. D.; Zhao, P.; Miller, M. J.; Dhaliwal, J. S.; Huertas-Vazquez, A.; Wu, X.; Qiao, R.; Soffer, J. M.; Rau, C.; Wang, Y.; Mikkola, H. K. A.; Lusis, A. J.; Ardehali, R. Genetic Regulation of Fibroblast Activation and Proliferation in Cardiac Fibrosis. Circulation 2018, 138 (12), 1224–1235.

He, C.; Hu, X.; Weston, T. A.; Jung, R. S.; Sandhu, J.; Huang, S.; Heizer, P.; Kim, J.; Ellison, R.; Xu, J.; Kilburn, M.; Bensinger, S. J.; Riezman, H.; Tontonoz, P.; Fong, L. G.; Jiang, H.; Young, S. G. Macrophages Release Plasma Membrane-Derived Particles Rich in Accessible Cholesterol. Proc Natl Acad Sci U S A 2018, 115 (36), E8499–E8508.

Erbilgin, A.; Seldin, M. M.; Wu, X.; Mehrabian, M.; Zhou, Z.; Qi, H.; Dabirian, K. S.; Sevag Packard, R. R.; Hsieh, W.; Bensinger, S. J.; Sinha, S.; Lusis, A. J. Transcription Factor Zhx2 Deficiency Reduces Atherosclerosis and Promotes Macrophage Apoptosis in Mice. Arterioscler Thromb Vasc Biol 2018, 38 (9), 2016–2027.

Patel, C. B.; Fazzari, E.; Chakhoyan, A.; Yao, J.; Raymond, C.; Nguyen, H.; Manoukian, J.; Nguyen, N.; Pope, W.; Cloughesy, T. F.; Nghiemphu, P. L.; Czernin, J.; Lai, A.; Ellingson, B. M. 18F-FDOPA PET and MRI Characteristics Correlate with Degree of Malignancy and Predict Survival in Treatment-Naïve Gliomas: A Cross-Sectional Study. J Neurooncol 2018, 139 (2), 399–409.

Andrews, A. M.; Cheng, X.; Altieri, S. C.; Yang, H. Bad Behavior: Improving Reproducibility in Behavior Testing. ACS Chem Neurosci 2018, 9 (8), 1904–1906.

Hilfenhaus, G.; Nguyen, D. P.; Freshman, J.; Prajapati, D.; Ma, F.; Song, D.; Ziyad, S.; Cuadrado, M.; Pellegrini, M.; Bustelo, X. R.; Iruela-Arispe, M. L. Vav3-Induced Cytoskeletal Dynamics Contribute to Heterotypic Properties of Endothelial Barriers. J Cell Biol 2018, 217 (8), 2813–2830.

Wilkinson, D. C.; Mellody, M.; Meneses, L. K.; Hope, A. C.; Dunn, B.; Gomperts, B. N. Development of a Three-Dimensional Bioengineering Technology to Generate Lung Tissue for Personalized Disease Modeling. Curr Protoc Stem Cell Biol 2018, 46 (1), e56.

Cheung, S. F.; Yee, M. F.; Le, N. K.; Wu, B. M.; Kamei, D. T. A One-Pot, Isothermal DNA Sample Preparation and Amplification Platform Utilizing Aqueous Two-Phase Systems. Anal Bioanal Chem 2018, 410 (21), 5255–5263.

Lee, H. N.; Mitra, M.; Bosompra, O.; Corney, D. C.; Johnson, E. L.; Rashed, N.; Ho, L. D.; Coller, H. A. RECK Isoforms Have Opposing Effects on Cell Migration. Mol Biol Cell 2018, 29 (15), 1825–1838.

Bryant, A. S.; Ruiz, F.; Gang, S. S.; Castelletto, M. L.; Lopez, J. B.; Hallem, E. A. A Critical Role for Thermosensation in Host Seeking by Skin-Penetrating Nematodes. Curr Biol 2018, 28 (14), 2338-2347.e6.

Wang, H.; Lee, Y. K.; Xue, C.; Guo, Z. Site-Specific Structural Order in Alzheimer’s Aβ42 Fibrils. R Soc Open Sci 2018, 5 (7), 180166.

Lu, N. T.; Liu, N. M.; Patel, D.; Vu, J. Q.; Liu, L.; Kim, C. Y.; Cho, P.; Khachatoorian, R.; Patel, N.; Magyar, C. E.; Ganapathy, E.; Arumugaswami, V.; Dasgupta, A.; French, S. W. Oncoprotein Stathmin Modulates Sensitivity to Apoptosis in Hepatocellular Carcinoma Cells During Hepatitis C Viral Replication. J Cell Death 2018, 11, 1179066018785141.

Xu, S.; Catapang, A.; Braas, D.; Stiles, L.; Doh, H. M.; Lee, J. T.; Graeber, T. G.; Damoiseaux, R.; Shirihai, O.; Herschman, H. R. A Precision Therapeutic Strategy for Hexokinase 1-Null, Hexokinase 2-Positive Cancers. Cancer Metab 2018, 6, 7.

Xu, S.; Catapang, A.; Doh, H. M.; Bayley, N. A.; Lee, J. T.; Braas, D.; Graeber, T. G.; Herschman, H. R. Hexokinase 2 Is Targetable for HK1 Negative, HK2 Positive Tumors from a Wide Variety of Tissues of Origin. J Nucl Med 2018, jnumed.118.212365.

Zhao, G.; Huang, B.-L.; Rigueur, D.; Wang, W.; Bhoot, C.; Charles, K. R.; Baek, J.; Mohan, S.; Jiang, J.; Lyons, K. M. CYR61/CCN1 Regulates Sclerostin Levels and Bone Maintenance. J Bone Miner Res 2018, 33 (6), 1076–1089.

Laks, D. R.; Oses-Prieto, J. A.; Alvarado, A. G.; Nakashima, J.; Chand, S.; Azzam, D. B.; Gholkar, A. A.; Sperry, J.; Ludwig, K.; Condro, M. C.; Nazarian, S.; Cardenas, A.; Shih, M. Y. S.; Damoiseaux, R.; France, B.; Orozco, N.; Visnyei, K.; Crisman, T. J.; Gao, F.; Torres, J. Z.; Coppola, G.; Burlingame, A. L.; Kornblum, H. I. A Molecular Cascade Modulates MAP1B and Confers Resistance to MTOR Inhibition in Human Glioblastoma. Neuro Oncol 2018, 20 (6), 764–775.

Lee, J. K.; Bangayan, N. J.; Chai, T.; Smith, B. A.; Pariva, T. E.; Yun, S.; Vashisht, A.; Zhang, Q.; Park, J. W.; Corey, E.; Huang, J.; Graeber, T. G.; Wohlschlegel, J.; Witte, O. N. Systemic Surfaceome Profiling Identifies Target Antigens for Immune-Based Therapy in Subtypes of Advanced Prostate Cancer. Proc Natl Acad Sci U S A 2018, 115 (19), E4473–E4482.

Ohashi, M.; Korsakova, E.; Allen, D.; Lee, P.; Fu, K.; Vargas, B. S.; Cinkornpumin, J.; Salas, C.; Park, J. C.; Germanguz, I.; Langerman, J.; Chronis, C.; Kuoy, E.; Tran, S.; Xiao, X.; Pellegrini, M.; Plath, K.; Lowry, W. E. Loss of MECP2 Leads to Activation of P53 and Neuronal Senescence. Stem Cell Reports 2018, 10 (5), 1453–1463.

Pastor, W. A.; Liu, W.; Chen, D.; Ho, J.; Kim, R.; Hunt, T. J.; Lukianchikov, A.; Liu, X.; Polo, J. M.; Jacobsen, S. E.; Clark, A. T. TFAP2C Regulates Transcription in Human Naive Pluripotency by Opening Enhancers. Nat Cell Biol 2018, 20 (5), 553–564.

Pan, D. Z.; Garske, K. M.; Alvarez, M.; Bhagat, Y. V.; Boocock, J.; Nikkola, E.; Miao, Z.; Raulerson, C. K.; Cantor, R. M.; Civelek, M.; Glastonbury, C. A.; Small, K. S.; Boehnke, M.; Lusis, A. J.; Sinsheimer, J. S.; Mohlke, K. L.; Laakso, M.; Pajukanta, P.; Ko, A. Integration of Human Adipocyte Chromosomal Interactions with Adipose Gene Expression Prioritizes Obesity-Related Genes from GWAS. Nat Commun 2018, 9 (1), 1512.

Vuong, C. K.; Wei, W.; Lee, J.-A.; Lin, C.-H.; Damianov, A.; de la Torre-Ubieta, L.; Halabi, R.; Otis, K. O.; Martin, K. C.; O’Dell, T. J.; Black, D. L. Rbfox1 Regulates Synaptic Transmission through the Inhibitory Neuron-Specific VSNARE Vamp1. Neuron 2018, 98 (1), 127-141.e7.

Paz, A.; Claxton, D. P.; Kumar, J. P.; Kazmier, K.; Bisignano, P.; Sharma, S.; Nolte, S. A.; Liwag, T. M.; Nayak, V.; Wright, E. M.; Grabe, M.; Mchaourab, H. S.; Abramson, J. Conformational Transitions of the Sodium-Dependent Sugar Transporter, VSGLT. Proc Natl Acad Sci U S A 2018, 115 (12), E2742–E2751.

Gell, J. J.; Zhao, J.; Chen, D.; Hunt, T. J.; Clark, A. T. PRDM14 Is Expressed in Germ Cell Tumors with Constitutive Overexpression Altering Human Germline Differentiation and Proliferation. Stem Cell Res 2018, 27, 46–56.

Chin, C. J.; Li, S.; Corselli, M.; Casero, D.; Zhu, Y.; He, C. B.; Hardy, R.; Péault, B.; Crooks, G. M. Transcriptionally and Functionally Distinct Mesenchymal Subpopulations Are Generated from Human Pluripotent Stem Cells. Stem Cell Reports 2018, 10 (2), 436–446.

Montecino-Rodriguez, E.; Casero, D.; Fice, M.; Le, J.; Dorshkind, K. Differential Expression of PU.1 and Key T Lineage Transcription Factors Distinguishes Fetal and Adult T Cell Development. J Immunol 2018, 200 (6), 2046–2056.

Long, J.; Hoban, M. D.; Cooper, A. R.; Kaufman, M. L.; Kuo, C. Y.; Campo-Fernandez, B.; Lumaquin, D.; Hollis, R. P.; Wang, X.; Kohn, D. B.; Romero, Z. Characterization of Gene Alterations Following Editing of the β-Globin Gene Locus in Hematopoietic Stem/Progenitor Cells. Mol Ther 2018, 26 (2), 468–479.

Cheung, S. F.; Yee, M. F.; Le, N. K.; Gomes, E. A.; Afrasiabi, Z.; Kamei, D. T. A Combined Aqueous Two-Phase System and Spot-Test Platform for the Rapid Detection of Escherichia Coli O157:H7 in Milk. SLAS Technol 2018, 23 (1), 57–63.

Du, Y.; Xin, L.; Shi, Y.; Zhang, T.-H.; Wu, N. C.; Dai, L.; Gong, D.; Brar, G.; Shu, S.; Luo, J.; Reiley, W.; Tseng, Y.-W.; Bai, H.; Wu, T.-T.; Wang, J.; Shu, Y.; Sun, R. Genome-Wide Identification of Interferon-Sensitive Mutations Enables Influenza Vaccine Design. Science 2018, 359 (6373), 290–296.

Patel, A. A.; Oztug Durer, Z. A.; van Loon, A. P.; Bremer, K. V.; Quinlan, M. E. Drosophila and Human FHOD Family Formin Proteins Nucleate Actin Filaments. J Biol Chem 2018, 293 (2), 532–540.

Tao, Y.; Yen, M.-R.; Chitiashvili, T.; Nakano, H.; Kim, R.; Hosohama, L.; Tan, Y. C.; Nakano, A.; Chen, P.-Y.; Clark, A. T. TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency. Stem Cell Reports 2018, 10 (1), 243–256.

Hicks, M. R.; Hiserodt, J.; Paras, K.; Fujiwara, W.; Eskin, A.; Jan, M.; Xi, H.; Young, C. S.; Evseenko, D.; Nelson, S. F.; Spencer, M. J.; Handel, B. V.; Pyle, A. D. ERBB3 and NGFR Mark a Distinct Skeletal Muscle Progenitor Cell in Human Development and HPSCs. Nat Cell Biol 2018, 20 (1), 46–57.

Mitra, M.; Ho, L. D.; Coller, H. A. An In Vitro Model of Cellular Quiescence in Primary Human Dermal Fibroblasts. Methods Mol Biol 2018, 1686, 27–47.

Hayden, E. Y.; Conovaloff, J. L.; Mason, A.; Bitan, G.; Teplow, D. B. Preparation of Pure Populations of Amyloid β-Protein Oligomers of Defined Size. Methods Mol Biol 2018, 1779, 3–12.

 

2017

Zhen, A.; Peterson, C. W.; Carrillo, M. A.; Reddy, S. S.; Youn, C. S.; Lam, B. B.; Chang, N. Y.; Martin, H. A.; Rick, J. W.; Kim, J.; Neel, N. C.; Rezek, V. K.; Kamata, M.; Chen, I. S. Y.; Zack, J. A.; Kiem, H.-P.; Kitchen, S. G. Long-Term Persistence and Function of Hematopoietic Stem Cell-Derived Chimeric Antigen Receptor T Cells in a Nonhuman Primate Model of HIV/AIDS. PLoS Pathog 2017, 13 (12), e1006753.

Nakano, H.; Minami, I.; Braas, D.; Pappoe, H.; Wu, X.; Sagadevan, A.; Vergnes, L.; Fu, K.; Morselli, M.; Dunham, C.; Ding, X.; Stieg, A. Z.; Gimzewski, J. K.; Pellegrini, M.; Clark, P. M.; Reue, K.; Lusis, A. J.; Ribalet, B.; Kurdistani, S. K.; Christofk, H.; Nakatsuji, N.; Nakano, A. Glucose Inhibits Cardiac Muscle Maturation through Nucleotide Biosynthesis. Elife 2017, 6, e29330.

Roychaudhuri, R.; Huynh, T.-P. V.; Whitaker, T. R.; Hodara, E.; Condron, M. M.; Teplow, D. B. A Critical Role of Ser26 Hydrogen Bonding in Aβ42 Assembly and Toxicity. Biochemistry 2017, 56 (48), 6321–6324.

Fisch, S. C.; Gimeno, M. L.; Phan, J. D.; Simerman, A. A.; Dumesic, D. A.; Perone, M. J.; Chazenbalk, G. D. Pluripotent Nontumorigenic Multilineage Differentiating Stress Enduring Cells (Muse Cells): A Seven-Year Retrospective. Stem Cell Res Ther 2017, 8 (1), 227.

Gang, S. S.; Castelletto, M. L.; Bryant, A. S.; Yang, E.; Mancuso, N.; Lopez, J. B.; Pellegrini, M.; Hallem, E. A. Targeted Mutagenesis in a Human-Parasitic Nematode. PLoS Pathog 2017, 13 (10), e1006675.

Kirsch, N.; Chang, L.-S.; Koch, S.; Glinka, A.; Dolde, C.; Colozza, G.; Benitez, M. D. J.; De Robertis, E. M.; Niehrs, C. Angiopoietin-like 4 Is a Wnt Signaling Antagonist That Promotes LRP6 Turnover. Dev Cell 2017, 43 (1), 71-82.e6.

Hayden, E. Y.; Hoi, K. K.; Lopez, J.; Inayathullah, M.; Condron, M. M.; Teplow, D. B. Identification of Key Regions and Residues Controlling Aβ Folding and Assembly. Sci Rep 2017, 7 (1), 12434.

Li, B.; Wang, X.; Choi, I. Y.; Wang, Y.-C.; Liu, S.; Pham, A. T.; Moon, H.; Smith, D. J.; Rao, D. S.; Boldin, M. P.; Yang, L. MiR-146a Modulates Autoreactive Th17 Cell Differentiation and Regulates Organ-Specific Autoimmunity. J Clin Invest 2017, 127 (10), 3702–3716.

Antonios, J. P.; Soto, H.; Everson, R. G.; Moughon, D. L.; Wang, A. C.; Orpilla, J.; Radu, C.; Ellingson, B. M.; Lee, J. T.; Cloughesy, T.; Phelps, M. E.; Czernin, J.; Liau, L. M.; Prins, R. M. Detection of Immune Responses after Immunotherapy in Glioblastoma Using PET and MRI. Proc Natl Acad Sci U S A 2017, 114 (38), 10220–10225.

Du, Y.; Chi, X.; Wang, C.; Jiang, J.; Kong, F.; Yan, H.; Wang, X.; Li, J.; Wu, N. C.; Dai, L.; Zhang, T.-H.; Shu, S.; Zhou, J.; Yoshizawa, J. M.; Li, X.; Bhattacharya, D.; Wu, T.-T.; Niu, J.; Sun, R. Quantifying Perinatal Transmission of Hepatitis B Viral Quasispecies by Tag Linkage Deep Sequencing. Sci Rep 2017, 7 (1), 10168.

Xue, C.; Lee, Y. K.; Tran, J.; Chang, D.; Guo, Z. A Mix-and-Click Method to Measure Amyloid-β Concentration with Sub-Micromolar Sensitivity. R Soc Open Sci 2017, 4 (8), 170325.

Zhang, Y.; Qin, W.; Lu, X.; Xu, J.; Huang, H.; Bai, H.; Li, S.; Lin, S. Programmable Base Editing of Zebrafish Genome Using a Modified CRISPR-Cas9 System. Nat Commun 2017, 8 (1), 118.

Fetherolf, M. M.; Boyd, S. D.; Taylor, A. B.; Kim, H. J.; Wohlschlegel, J. A.; Blackburn, N. J.; Hart, P. J.; Winge, D. R.; Winkler, D. D. Copper-Zinc Superoxide Dismutase Is Activated through a Sulfenic Acid Intermediate at a Copper Ion Entry Site. J Biol Chem 2017, 292 (29), 12025–12040.

Scumpia, P. O.; Botten, G. A.; Norman, J. S.; Kelly-Scumpia, K. M.; Spreafico, R.; Ruccia, A. R.; Purbey, P. K.; Thomas, B. J.; Modlin, R. L.; Smale, S. T. Opposing Roles of Toll-like Receptor and Cytosolic DNA-STING Signaling Pathways for Staphylococcus Aureus Cutaneous Host Defense. PLoS Pathog 2017, 13 (7), e1006496.

Antonios, J. P.; Soto, H.; Everson, R. G.; Moughon, D.; Orpilla, J. R.; Shin, N. P.; Sedighim, S.; Treger, J.; Odesa, S.; Tucker, A.; Yong, W. H.; Li, G.; Cloughesy, T. F.; Liau, L. M.; Prins, R. M. Immunosuppressive Tumor-Infiltrating Myeloid Cells Mediate Adaptive Immune Resistance via a PD-1/PD-L1 Mechanism in Glioblastoma. Neuro Oncol 2017, 19 (6), 796–807.

Ding, Y.; Colozza, G.; Zhang, K.; Moriyama, Y.; Ploper, D.; Sosa, E. A.; Benitez, M. D. J.; De Robertis, E. M. Genome-Wide Analysis of Dorsal and Ventral Transcriptomes of the Xenopus Laevis Gastrula. Dev Biol 2017, 426 (2), 176–187.

Einstein, M. C.; Polack, P.-O.; Tran, D. T.; Golshani, P. Visually Evoked 3-5 Hz Membrane Potential Oscillations Reduce the Responsiveness of Visual Cortex Neurons in Awake Behaving Mice. J Neurosci 2017, 37 (20), 5084–5098.

Alam, M.; Garcia-Alias, G.; Jin, B.; Keyes, J.; Zhong, H.; Roy, R. R.; Gerasimenko, Y.; Lu, D. C.; Edgerton, V. R. Electrical Neuromodulation of the Cervical Spinal Cord Facilitates Forelimb Skilled Function Recovery in Spinal Cord Injured Rats. Exp Neurol 2017, 291, 141–150.

Sosa, E.; Kim, R.; Rojas, E. J.; Hosohama, L.; Hennebold, J. D.; Orwig, K. E.; Clark, A. T. An Integration-Free, Virus-Free Rhesus Macaque Induced Pluripotent Stem Cell Line (RiPSC90) from Embryonic Fibroblasts. Stem Cell Res 2017, 21, 5–8.

Seet, C. S.; He, C.; Bethune, M. T.; Li, S.; Chick, B.; Gschweng, E. H.; Zhu, Y.; Kim, K.; Kohn, D. B.; Baltimore, D.; Crooks, G. M.; Montel-Hagen, A. Generation of Mature T Cells from Human Hematopoietic Stem and Progenitor Cells in Artificial Thymic Organoids. Nat Methods 2017, 14 (5), 521–530.

Ding, Y.; Ploper, D.; Sosa, E. A.; Colozza, G.; Moriyama, Y.; Benitez, M. D. J.; Zhang, K.; Merkurjev, D.; De Robertis, E. M. Spemann Organizer Transcriptome Induction by Early Beta-Catenin, Wnt, Nodal, and Siamois Signals in Xenopus Laevis. Proc Natl Acad Sci U S A 2017, 114 (15), E3081–E3090.

Cevallos, J. A.; Okubo, R. P.; Perlman, S. J.; Hallem, E. A. Olfactory Preferences of the Parasitic Nematode Howardula Aoronymphium and Its Insect Host Drosophila Falleni. J Chem Ecol 2017, 43 (4), 362–373.

Lillo, M. A.; Nichols, C.; Perry, C.; Runke, S.; Krutilina, R.; Seagroves, T. N.; Miranda-Carboni, G. A.; Krum, S. A. Methylparaben Stimulates Tumor Initiating Cells in ER+ Breast Cancer Models. J Appl Toxicol 2017, 37 (4), 417–425.

Lillo, M. A.; Nichols, C.; Seagroves, T. N.; Miranda-Carboni, G. A.; Krum, S. A. Bisphenol A Induces Sox2 in ER+ Breast Cancer Stem-Like Cells. Horm Cancer 2017, 8 (2), 90–99.

Chen, A. L.; Moon, A. S.; Bell, H. N.; Huang, A. S.; Vashisht, A. A.; Toh, J. Y.; Lin, A. H.; Nadipuram, S. M.; Kim, E. W.; Choi, C. P.; Wohlschlegel, J. A.; Bradley, P. J. Novel Insights into the Composition and Function of the Toxoplasma IMC Sutures. Cell Microbiol 2017, 19 (4).

Khialeeva, E.; Chou, J. W.; Allen, D. E.; Chiu, A. M.; Bensinger, S. J.; Carpenter, E. M. Reelin Deficiency Delays Mammary Tumor Growth and Metastatic Progression. J Mammary Gland Biol Neoplasia 2017, 22 (1), 59–69.

Yvone, G. M.; Zhao-Fleming, H. H.; Udeochu, J. C.; Chavez-Martinez, C. L.; Wang, A.; Hirose-Ikeda, M.; Phelps, P. E. Disabled-1 Dorsal Horn Spinal Cord Neurons Co-Express Lmx1b and Function in Nociceptive Circuits. Eur J Neurosci 2017, 45 (5), 733–747.

Chambers, M.; Turki-Judeh, W.; Kim, M. W.; Chen, K.; Gallaher, S. D.; Courey, A. J. Mechanisms of Groucho-Mediated Repression Revealed by Genome-Wide Analysis of Groucho Binding and Activity. BMC Genomics 2017, 18 (1), 215.

Zieba, J.; Zhang, W.; Chong, J. X.; Forlenza, K. N.; Martin, J. H.; Heard, K.; Grange, D. K.; Butler, M. G.; Kleefstra, T.; Lachman, R. S.; Nickerson, D.; Regnier, M.; Cohn, D. H.; Bamshad, M.; Krakow, D. A Postnatal Role for Embryonic Myosin Revealed by MYH3 Mutations That Alter TGFβ Signaling and Cause Autosomal Dominant Spondylocarpotarsal Synostosis. Sci Rep 2017, 7, 41803.

Graham, N. A.; Minasyan, A.; Lomova, A.; Cass, A.; Balanis, N. G.; Friedman, M.; Chan, S.; Zhao, S.; Delgado, A.; Go, J.; Beck, L.; Hurtz, C.; Ng, C.; Qiao, R.; Ten Hoeve, J.; Palaskas, N.; Wu, H.; Müschen, M.; Multani, A. S.; Port, E.; Larson, S. M.; Schultz, N.; Braas, D.; Christofk, H. R.; Mellinghoff, I. K.; Graeber, T. G. Recurrent Patterns of DNA Copy Number Alterations in Tumors Reflect Metabolic Selection Pressures. Mol Syst Biol 2017, 13 (2), 914.

Xi, H.; Fujiwara, W.; Gonzalez, K.; Jan, M.; Liebscher, S.; Van Handel, B.; Schenke-Layland, K.; Pyle, A. D. In Vivo Human Somitogenesis Guides Somite Development from HPSCs. Cell Rep 2017, 18 (6), 1573–1585.

Pillai, I. C. L.; Li, S.; Romay, M.; Lam, L.; Lu, Y.; Huang, J.; Dillard, N.; Zemanova, M.; Rubbi, L.; Wang, Y.; Lee, J.; Xia, M.; Liang, O.; Xie, Y.-H.; Pellegrini, M.; Lusis, A. J.; Deb, A. Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification. Cell Stem Cell 2017, 20 (2), 218-232.e5.

Hayden, E. Y.; Conovaloff, J. L.; Mason, A.; Bitan, G.; Teplow, D. B. Preparation of Pure Populations of Covalently Stabilized Amyloid β-Protein Oligomers of Specific Sizes. Anal Biochem 2017, 518, 78–85.

Argus, J. P.; Yu, A. K.; Wang, E. S.; Williams, K. J.; Bensinger, S. J. An Optimized Method for Measuring Fatty Acids and Cholesterol in Stable Isotope-Labeled Cells. J Lipid Res 2017, 58 (2), 460–468.

Kermgard, E.; Yang, Z.; Michel, A.-M.; Simari, R.; Wong, J.; Ibba, M.; Lazazzera, B. A. Quality Control by Isoleucyl-TRNA Synthetase of Bacillus Subtilis Is Required for Efficient Sporulation. Sci Rep 2017, 7, 41763.

Dai, X.; Li, Z.; Lai, M.; Shu, S.; Du, Y.; Zhou, Z. H.; Sun, R. In Situ Structures of the Genome and Genome-Delivery Apparatus in a Single-Stranded RNA Virus. Nature 2017, 541 (7635), 112–116.

Gaeta, X.; Le, L.; Lin, Y.; Xie, Y.; Lowry, W. E. Defining Transcriptional Regulatory Mechanisms for Primary Let-7 MiRNAs. PLoS One 2017, 12 (1), e0169237.

Zhen, A.; Rezek, V.; Youn, C.; Lam, B.; Chang, N.; Rick, J.; Carrillo, M.; Martin, H.; Kasparian, S.; Syed, P.; Rice, N.; Brooks, D. G.; Kitchen, S. G. Targeting Type I Interferon-Mediated Activation Restores Immune Function in Chronic HIV Infection. J Clin Invest 2017, 127 (1), 260–268.

Hickey, M. J.; Zheng, Y.; Valenzuela, N.; Zhang, Q.; Krystal, C.; Lum, E.; Tsai, E. W.; Lipshutz, G. S.; Gritsch, H. A.; Danovitch, G.; Veale, J.; Gjertson, D.; Cecka, M.; Reed, E. F. New Priorities: Analysis of the New Kidney Allocation System on UCLA Patients Transplanted from the Deceased Donor Waitlist. Hum Immunol 2017, 78 (1), 41–48.

Tran, J.; Chang, D.; Hsu, F.; Wang, H.; Guo, Z. Cross-Seeding between Aβ40 and Aβ42 in Alzheimer’s Disease. FEBS Lett 2017, 591 (1), 177–185.

Chen, D.; Liu, W.; Lukianchikov, A.; Hancock, G. V.; Zimmerman, J.; Lowe, M. G.; Kim, R.; Galic, Z.; Irie, N.; Surani, M. A.; Jacobsen, S. E.; Clark, A. T. Germline Competency of Human Embryonic Stem Cells Depends on Eomesodermin. Biol Reprod 2017, 97 (6), 850–861.

Arakawa, C.; Ng, R.; Tan, S.; Kim, S.; Wu, B.; Lee, M. Photopolymerizable Chitosan-Collagen Hydrogels for Bone Tissue Engineering. J Tissue Eng Regen Med 2017, 11 (1), 164–174.

2016

Smith, D. J.; Lin, L. J.; Moon, H.; Pham, A. T.; Wang, X.; Liu, S.; Ji, S.; Rezek, V.; Shimizu, S.; Ruiz, M.; Lam, J.; Janzen, D. M.; Memarzadeh, S.; Kohn, D. B.; Zack, J. A.; Kitchen, S. G.; An, D. S.; Yang, L. Propagating Humanized BLT Mice for the Study of Human Immunology and Immunotherapy. Stem Cells Dev 2016, 25 (24), 1863–1873.

Simerman, A. A.; Phan, J. D.; Dumesic, D. A.; Chazenbalk, G. D. Muse Cells: Nontumorigenic Pluripotent Stem Cells Present in Adult Tissues-A Paradigm Shift in Tissue Regeneration and Evolution. Stem Cells Int 2016, 2016, 1463258.

Hines, J. P.; Smith, A. T.; Jacob, J. P.; Lukat-Rodgers, G. S.; Barr, I.; Rodgers, K. R.; Guo, F.; Burstyn, J. N. CO and NO Bind to Fe(II) DiGeorge Critical Region 8 Heme but Do Not Restore Primary MicroRNA Processing Activity. J Biol Inorg Chem 2016, 21 (8), 1021–1035.

Lee, P. C.; Truong, B.; Vega-Crespo, A.; Gilmore, W. B.; Hermann, K.; Angarita, S. A.; Tang, J. K.; Chang, K. M.; Wininger, A. E.; Lam, A. K.; Schoenberg, B. E.; Cederbaum, S. D.; Pyle, A. D.; Byrne, J. A.; Lipshutz, G. S. Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-Mediated Genomic Addition to Arginase-Deficient Induced Pluripotent Stem Cells. Mol Ther Nucleic Acids 2016, 5 (11), e394.

Bramble, M. S.; Roach, L.; Lipson, A.; Vashist, N.; Eskin, A.; Ngun, T.; Gosschalk, J. E.; Klein, S.; Barseghyan, H.; Arboleda, V. A.; Vilain, E. Sex-Specific Effects of Testosterone on the Sexually Dimorphic Transcriptome and Epigenome of Embryonic Neural Stem/Progenitor Cells. Sci Rep 2016, 6, 36916.

Gong, D.; Kim, Y. H.; Xiao, Y.; Du, Y.; Xie, Y.; Lee, K. K.; Feng, J.; Farhat, N.; Zhao, D.; Shu, S.; Dai, X.; Chanda, S. K.; Rana, T. M.; Krogan, N. J.; Sun, R.; Wu, T.-T. A Herpesvirus Protein Selectively Inhibits Cellular MRNA Nuclear Export. Cell Host Microbe 2016, 20 (5), 642–653.

Franklin, S.; Kimball, T.; Rasmussen, T. L.; Rosa-Garrido, M.; Chen, H.; Tran, T.; Miller, M. R.; Gray, R.; Jiang, S.; Ren, S.; Wang, Y.; Tucker, H. O.; Vondriska, T. M. The Chromatin-Binding Protein Smyd1 Restricts Adult Mammalian Heart Growth. Am J Physiol Heart Circ Physiol 2016, 311 (5), H1234–H1247.

Jiang, J.; Leong, N. L.; Khalique, U.; Phan, T. M.; Lyons, K. M.; Luck, J. V. Connective Tissue Growth Factor (CTGF/CCN2) in Haemophilic Arthropathy and Arthrofibrosis: A Histological Analysis. Haemophilia 2016, 22 (6), e527–e536.

Du, Y.; Wu, N. C.; Jiang, L.; Zhang, T.; Gong, D.; Shu, S.; Wu, T.-T.; Sun, R. Annotating Protein Functional Residues by Coupling High-Throughput Fitness Profile and Homologous-Structure Analysis. mBio 2016, 7 (6), e01801-16.

Wang, W.; Song, B.; Anbarchian, T.; Shirazyan, A.; Sadik, J. E.; Lyons, K. M. Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate. PLoS Genet 2016, 12 (10), e1006352.

Hargan-Calvopina, J.; Taylor, S.; Cook, H.; Hu, Z.; Lee, S. A.; Yen, M.-R.; Chiang, Y.-S.; Chen, P.-Y.; Clark, A. T. Stage-Specific Demethylation in Primordial Germ Cells Safeguards against Precocious Differentiation. Dev Cell 2016, 39 (1), 75–86.

Gu, W.; Gaeta, X.; Sahakyan, A.; Chan, A. B.; Hong, C. S.; Kim, R.; Braas, D.; Plath, K.; Lowry, W. E.; Christofk, H. R. Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State. Cell Stem Cell 2016, 19 (4), 476–490.

Montecino-Rodriguez, E.; Fice, M.; Casero, D.; Berent-Maoz, B.; Barber, C. L.; Dorshkind, K. Distinct Genetic Networks Orchestrate the Emergence of Specific Waves of Fetal and Adult B-1 and B-2 Development. Immunity 2016, 45 (3), 527–539.

TeSlaa, T.; Chaikovsky, A. C.; Lipchina, I.; Escobar, S. L.; Hochedlinger, K.; Huang, J.; Graeber, T. G.; Braas, D.; Teitell, M. A. α-Ketoglutarate Accelerates the Initial Differentiation of Primed Human Pluripotent Stem Cells. Cell Metab 2016, 24 (3), 485–493.

Wang, C.-W.; Purkayastha, A.; Jones, K. T.; Thaker, S. K.; Banerjee, U. In Vivo Genetic Dissection of Tumor Growth and the Warburg Effect. Elife 2016, 5, e18126.

Hoban, M. D.; Lumaquin, D.; Kuo, C. Y.; Romero, Z.; Long, J.; Ho, M.; Young, C. S.; Mojadidi, M.; Fitz-Gibbon, S.; Cooper, A. R.; Lill, G. R.; Urbinati, F.; Campo-Fernandez, B.; Bjurstrom, C. F.; Pellegrini, M.; Hollis, R. P.; Kohn, D. B. CRISPR/Cas9-Mediated Correction of the Sickle Mutation in Human CD34+ Cells. Mol Ther 2016, 24 (9), 1561–1569.

Matynia, A.; Nguyen, E.; Sun, X.; Blixt, F. W.; Parikh, S.; Kessler, J.; Pérez de Sevilla Müller, L.; Habib, S.; Kim, P.; Wang, Z. Z.; Rodriguez, A.; Charles, A.; Nusinowitz, S.; Edvinsson, L.; Barnes, S.; Brecha, N. C.; Gorin, M. B. Peripheral Sensory Neurons Expressing Melanopsin Respond to Light. Front Neural Circuits 2016, 10, 60.

Sung, K.; Ding, Y.; Ma, J.; Chen, H.; Huang, V.; Cheng, M.; Yang, C. F.; Kim, J. T.; Eguchi, D.; Di Carlo, D.; Hsiai, T. K.; Nakano, A.; Kulkarni, R. P. Simplified Three-Dimensional Tissue Clearing and Incorporation of Colorimetric Phenotyping. Sci Rep 2016, 6, 30736.

Nadipuram, S. M.; Kim, E. W.; Vashisht, A. A.; Lin, A. H.; Bell, H. N.; Coppens, I.; Wohlschlegel, J. A.; Bradley, P. J. In Vivo Biotinylation of the Toxoplasma Parasitophorous Vacuole Reveals Novel Dense Granule Proteins Important for Parasite Growth and Pathogenesis. mBio 2016, 7 (4), e00808-16.

Ruscetti, M.; Dadashian, E. L.; Guo, W.; Quach, B.; Mulholland, D. J.; Park, J. W.; Tran, L. M.; Kobayashi, N.; Bianchi-Frias, D.; Xing, Y.; Nelson, P. S.; Wu, H. HDAC Inhibition Impedes Epithelial-Mesenchymal Plasticity and Suppresses Metastatic, Castration-Resistant Prostate Cancer. Oncogene 2016, 35 (29), 3781–3795.

Vega-Crespo, A.; Truong, B.; Hermann, K. J.; Awe, J. P.; Chang, K. M.; Lee, P. C.; Schoenberg, B. E.; Wu, L.; Byrne, J. A.; Lipshutz, G. S. Investigating the Functionality of an OCT4-Short Response Element in Human Induced Pluripotent Stem Cells. Mol Ther Methods Clin Dev 2016, 3, 16050.

Izquierdo, A.; Pozos, H.; Torre, A. D. L.; DeShields, S.; Cevallos, J.; Rodriguez, J.; Stolyarova, A. Sex Differences, Learning Flexibility, and Striatal Dopamine D1 and D2 Following Adolescent Drug Exposure in Rats. Behav Brain Res 2016, 308, 104–114.

Antonios, J. P.; Soto, H.; Everson, R. G.; Orpilla, J.; Moughon, D.; Shin, N.; Sedighim, S.; Yong, W. H.; Li, G.; Cloughesy, T. F.; Liau, L. M.; Prins, R. M. PD-1 Blockade Enhances the Vaccination-Induced Immune Response in Glioma. JCI Insight 2016, 1 (10), e87059. https://doi.org/10.1172/jci.insight.87059.

Zhen, A.; Rezek, V.; Youn, C.; Rick, J.; Lam, B.; Chang, N.; Zack, J.; Kamata, M.; Kitchen, S. Stem-Cell Based Engineered Immunity Against HIV Infection in the Humanized Mouse Model. J Vis Exp 2016, No. 113.

Rodríguez, A.; Gonzalez, L.; Ko, A.; Alvarez, M.; Miao, Z.; Bhagat, Y.; Nikkola, E.; Cruz-Bautista, I.; Arellano-Campos, O.; Muñoz-Hernández, L. L.; Ordóñez-Sánchez, M.-L.; Rodriguez-Guillen, R.; Mohlke, K. L.; Laakso, M.; Tusie-Luna, T.; Aguilar-Salinas, C. A.; Pajukanta, P. Molecular Characterization of the Lipid Genome-Wide Association Study Signal on Chromosome 18q11.2 Implicates HNF4A-Mediated Regulation of the TMEM241 Gene. Arterioscler Thromb Vasc Biol 2016, 36 (7), 1350–1355.

Dou, D. R.; Calvanese, V.; Sierra, M. I.; Nguyen, A. T.; Minasian, A.; Saarikoski, P.; Sasidharan, R.; Ramirez, C. M.; Zack, J. A.; Crooks, G. M.; Galic, Z.; Mikkola, H. K. A. Medial HOXA Genes Demarcate Haematopoietic Stem Cell Fate during Human Development. Nat Cell Biol 2016, 18 (6), 595–606.

Macey, P. M.; Rieken, N. S.; Kumar, R.; Ogren, J. A.; Middlekauff, H. R.; Wu, P.; Woo, M. A.; Harper, R. M. Sex Differences in Insular Cortex Gyri Responses to the Valsalva Maneuver. Front Neurol 2016, 7, 87.

Khankan, R. R.; Griffis, K. G.; Haggerty-Skeans, J. R.; Zhong, H.; Roy, R. R.; Edgerton, V. R.; Phelps, P. E. Olfactory Ensheathing Cell Transplantation after a Complete Spinal Cord Transection Mediates Neuroprotective and Immunomodulatory Mechanisms to Facilitate Regeneration. J Neurosci 2016, 36 (23), 6269–6286.

Hale, C. J.; Potok, M. E.; Lopez, J.; Do, T.; Liu, A.; Gallego-Bartolome, J.; Michaels, S. D.; Jacobsen, S. E. Identification of Multiple Proteins Coupling Transcriptional Gene Silencing to Genome Stability in Arabidopsis Thaliana. PLoS Genet 2016, 12 (6), e1006092.

Cai, D. J.; Aharoni, D.; Shuman, T.; Shobe, J.; Biane, J.; Song, W.; Wei, B.; Veshkini, M.; La-Vu, M.; Lou, J.; Flores, S. E.; Kim, I.; Sano, Y.; Zhou, M.; Baumgaertel, K.; Lavi, A.; Kamata, M.; Tuszynski, M.; Mayford, M.; Golshani, P.; Silva, A. J. A Shared Neural Ensemble Links Distinct Contextual Memories Encoded Close in Time. Nature 2016, 534 (7605), 115–118.

Ear, J.; Hsueh, J.; Nguyen, M.; Zhang, Q.; Sung, V.; Chopra, R.; Sakamoto, K. M.; Lin, S. A Zebrafish Model of 5q-Syndrome Using CRISPR/Cas9 Targeting RPS14 Reveals a P53-Independent and P53-Dependent Mechanism of Erythroid Failure. J Genet Genomics 2016, 43 (5), 307–318.

Nguyen, T. P.; Sovari, A. A.; Pezhouman, A.; Iyer, S.; Cao, H.; Ko, C. Y.; Bapat, A.; Vahdani, N.; Ghanim, M.; Fishbein, M. C.; Karagueuzian, H. S. Increased Susceptibility of Spontaneously Hypertensive Rats to Ventricular Tachyarrhythmias in Early Hypertension. J Physiol 2016, 594 (6), 1689–1707.

Dumesic, D. A.; Guedikian, A. A.; Madrigal, V. K.; Phan, J. D.; Hill, D. L.; Alvarez, J. P.; Chazenbalk, G. D. Cumulus Cell Mitochondrial Resistance to Stress In Vitro Predicts Oocyte Development During Assisted Reproduction. J Clin Endocrinol Metab 2016, 101 (5), 2235–2245.

Hsu, M.; Sedighim, S.; Wang, T.; Antonios, J. P.; Everson, R. G.; Tucker, A. M.; Du, L.; Emerson, R.; Yusko, E.; Sanders, C.; Robins, H. S.; Yong, W. H.; Davidson, T. B.; Li, G.; Liau, L. M.; Prins, R. M. TCR Sequencing Can Identify and Track Glioma-Infiltrating T Cells after DC Vaccination. Cancer Immunol Res 2016, 4 (5), 412–418.

Chin, C. J.; Cooper, A. R.; Lill, G. R.; Evseenko, D.; Zhu, Y.; He, C. B.; Casero, D.; Pellegrini, M.; Kohn, D. B.; Crooks, G. M. Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors. Stem Cells 2016, 34 (5), 1239–1250.

Damianov, A.; Ying, Y.; Lin, C.-H.; Lee, J.-A.; Tran, D.; Vashisht, A. A.; Bahrami-Samani, E.; Xing, Y.; Martin, K. C.; Wohlschlegel, J. A.; Black, D. L. Rbfox Proteins Regulate Splicing as Part of a Large Multiprotein Complex LASR. Cell 2016, 165 (3), 606–619.

Gu, L.; Tran, J.; Jiang, L.; Guo, Z. A New Structural Model of Alzheimer’s Aβ42 Fibrils Based on Electron Paramagnetic Resonance Data and Rosetta Modeling. J Struct Biol 2016, 194 (1), 61–67.

Wang, K.; Peng, E. D.; Huang, A. S.; Xia, D.; Vermont, S. J.; Lentini, G.; Lebrun, M.; Wastling, J. M.; Bradley, P. J. Identification of Novel O-Linked Glycosylated Toxoplasma Proteins by Vicia Villosa Lectin Chromatography. PLoS One 2016, 11 (3), e0150561.

Tong, A.-J.; Liu, X.; Thomas, B. J.; Lissner, M. M.; Baker, M. R.; Senagolage, M. D.; Allred, A. L.; Barish, G. D.; Smale, S. T. A Stringent Systems Approach Uncovers Gene-Specific Mechanisms Regulating Inflammation. Cell 2016, 165 (1), 165–179.

Pastor, W. A.; Chen, D.; Liu, W.; Kim, R.; Sahakyan, A.; Lukianchikov, A.; Plath, K.; Jacobsen, S. E.; Clark, A. T. Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory. Cell Stem Cell 2016, 18 (3), 323–329.

Gholkar, A. A.; Senese, S.; Lo, Y.-C.; Vides, E.; Contreras, E.; Hodara, E.; Capri, J.; Whitelegge, J. P.; Torres, J. Z. The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division. Cell Rep 2016, 14 (2), 180–188.

2015

Parvatiyar, M. S.; Marshall, J. L.; Nguyen, R. T.; Jordan, M. C.; Richardson, V. A.; Roos, K. P.; Crosbie-Watson, R. H. Sarcospan Regulates Cardiac Isoproterenol Response and Prevents Duchenne Muscular Dystrophy-Associated Cardiomyopathy. J Am Heart Assoc 2015, 4 (12), e002481.

York, A. G.; Williams, K. J.; Argus, J. P.; Zhou, Q. D.; Brar, G.; Vergnes, L.; Gray, E. E.; Zhen, A.; Wu, N. C.; Yamada, D. H.; Cunningham, C. R.; Tarling, E. J.; Wilks, M. Q.; Casero, D.; Gray, D. H.; Yu, A. K.; Wang, E. S.; Brooks, D. G.; Sun, R.; Kitchen, S. G.; Wu, T.-T.; Reue, K.; Stetson, D. B.; Bensinger, S. J. Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling. Cell 2015, 163 (7), 1716–1729.

Feng, J.; Gong, D.; Fu, X.; Wu, T.-T.; Wang, J.; Chang, J.; Zhou, J.; Lu, G.; Wang, Y.; Sun, R. M1 of Murine Gamma-Herpesvirus 68 Induces Endoplasmic Reticulum Chaperone Production. Sci Rep 2015, 5, 17228.

Briot, A.; Civelek, M.; Seki, A.; Hoi, K.; Mack, J. J.; Lee, S. D.; Kim, J.; Hong, C.; Yu, J.; Fishbein, G. A.; Vakili, L.; Fogelman, A. M.; Fishbein, M. C.; Lusis, A. J.; Tontonoz, P.; Navab, M.; Berliner, J. A.; Iruela-Arispe, M. L. Endothelial NOTCH1 Is Suppressed by Circulating Lipids and Antagonizes Inflammation during Atherosclerosis. J Exp Med 2015, 212 (12), 2147–2163.

Arcizet, F.; Mirpour, K.; Foster, D. J.; Charpentier, C. J.; Bisley, J. W. LIP Activity in the Interstimulus Interval of a Change Detection Task Biases the Behavioral Response. J Neurophysiol 2015, 114 (5), 2637–2648.

Upton, M.; Lotfipour, S. Α2-Null Mutant Mice Have Altered Levels of Neuronal Activity in Restricted Midbrain and Limbic Brain Regions during Nicotine Withdrawal as Demonstrated by Cfos Expression. Biochem Pharmacol 2015, 97 (4), 558–565.

Tariq, M.; Lum, M. R.; Chong, A. W.; Amirapu, A. B.; Hameed, S.; Hirsch, A. M. A Reliable Method for the Selection and Confirmation of Transconjugants of Plant Growth-Promoting Bacteria Especially Plant-Associated Burkholderia Spp. J Microbiol Methods 2015, 117, 49–53.

Sanchez, D. J.; Miranda, D.; Marsden, M. D.; Dizon, T. M. A.; Bontemps, J. R.; Davila, S. J.; Del Mundo, L. E.; Ha, T.; Senaati, A.; Zack, J. A.; Cheng, G. Disruption of Type I Interferon Induction by HIV Infection of T Cells. PLoS One 2015, 10 (9), e0137951.

Oliveros-Etter, M.; Li, Z.; Nee, K.; Hosohama, L.; Hargan-Calvopina, J.; Lee, S. A.; Joti, P.; Yu, J.; Clark, A. T. PGC Reversion to Pluripotency Involves Erasure of DNA Methylation from Imprinting Control Centers Followed by Locus-Specific Re-Methylation. Stem Cell Reports 2015, 5 (3), 337–349.

Lluri, G.; Huang, V.; Touma, M.; Liu, X.; Harmon, A. W.; Nakano, A. Hematopoietic Progenitors Are Required for Proper Development of Coronary Vasculature. J Mol Cell Cardiol 2015, 86, 199–207.

Sen, S.; Kawahara, B.; Gupta, D.; Tsai, R.; Khachatryan, M.; Roy-Chowdhuri, S.; Bose, S.; Yoon, A.; Faull, K.; Farias-Eisner, R.; Chaudhuri, G. Role of Cystathionine β-Synthase in Human Breast Cancer. Free Radic Biol Med 2015, 86, 228–238.

Yamin, G., Huynh, T.P., and Teplow, D.B. (2015). Design and Characterization of Chemically Stabilized Abeta42 Oligomers. Biochemistry 54, 5315-5321.

Zhen, A., Kamata, M., Rezek, V., Rick, J., Levin, B., Kasparian, S., Chen, I.S., Yang, O.O., Zack, J.A., and Kitchen, S.G. (2015). HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem Cells. Molecular Therapy 23, 1358-1367.

Morselli, M., Pastor, W.A., Montanini, B., Nee, K., Ferrari, R., Fu, K., Bonora, G., Rubbi, L., Clark, A.T., Ottonello, S., et al. (2015). In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse. eLife 4,e06205.

Oztug Durer, Z.A., McGillivary, R.M., Kang, H., Elam, W.A., Vizcarra, C.L., Hanein, D., De La Cruz, E.M., Reisler, E., and Quinlan, M.E. (2015). Metavinculin Tunes the Flexibility and the Architecture of Vinculin-Induced Bundles of Actin Filaments. Journal of Molecular Biology 427, 2782-2798.

Ear, J., Huang, H., Wilson, T., Tehrani, Z., Lindgren, A., Sung, V., Laadem, A., Daniel, T.O., Chopra, R., and Lin, S. (2015). RAP-011 improves erythropoiesis in zebrafish model of Diamond-Blackfan anemia through antagonizing lefty1. Blood 126, 880-890.

Thames, A.D., Sayegh, P., Terashima, K., Foley, J.M., Cho, A., Arentoft, A., Hinkin, C.H., and Bookheimer, S.Y. (2015). Increased subcortical neural activity among HIV+ individuals during a lexical retrieval task. Neurobiology of disease 92, 175-182.

Evdokimov, N.M., Clark, P.M., Flores, G., Chai, T., Faull, K.F., Phelps, M.E., Witte, O.N., and Jung, M.E. (2015). Development of 2-Deoxy-2-[(18)F]fluororibose for Positron Emission Tomography Imaging Liver Function in Vivo. Journal of Medicinal Chemistry 58, 5538-5547.

Nixon, C.C., Schwartz, B.H., Dixit, D., Zack, J.A., and Vatakis, D.N. (2015). Cocaine exposure impairs multineage hematopoiesis of human hematopoietic progenitor cells mediated by the sigma-1 receptor. Scientific Reports 5, 8670.

Hargan Calvopina, J., Cook, H., Vincent, J., Nee, K., and Clark, A. (2015). The Aorta Gonad Mesonephros organ culture recapitulates 5hmC reorganization and replication-dependent and independent loss of DNA methylation in the germline. Stem Cells and Development.

Ruscetti, M., Quach, B., Dadashian, E.L., Mulholland, D.J., and Wu, H. (2015). Tracking and Functional Characterization of Epithelial-Mesenchymal Transition and Mesenchymal Tumor Cells During Prostate Cancer Metastasis. Cancer research 75, 3781-3795.

Kim, S.G., Lowe, E.L., Dixit, D., Youn, C.S., Kim, I.J., Jung, J.B., Rovner, R., Zack, J.A., and Vatakis, D.N. (2015). Cocaine-mediated impact on HIV infection in humanized BLT mice. Scientific Reports 5, 10010.

Domigan, C.K., Warren, C.M., Antanesian, V., Happel, K., Ziyad, S., Lee, S., Krall, A., Duan, L., Torres-Collado, A.X., Castellani, L.W., et al. (2015). Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy. Journal of Cell Science 128, 2236-2248.

Lissner, M.M., Thomas, B.J., Wee, K., Tong, A.J., Kollmann, T.R., and Smale, S.T. (2015). Age-Related Gene Expression Differences in Monocytes from Human Neonates, Young Adults, and Older Adults. PloS One 10, e0132061.

Gkountela, S.; Zhang, K. X.; Shafiq, T. A.; Liao, W.-W.; Hargan-Calvopiña, J.; Chen, P.-Y.; Clark, A. T. DNA Demethylation Dynamics in the Human Prenatal Germline. Cell 2015, 161 (6), 1425–1436.

Wu, P.; Bandettini, P. A.; Harper, R. M.; Handwerker, D. A. Effects of Thoracic Pressure Changes on MRI Signals in the Brain. J Cereb Blood Flow Metab 2015, 35 (6), 1024–1032.

Kong, J.H., Yang, L., Dessaud, E., Chuang, K., Moore, D.M., Rohatgi, R., Briscoe, J., and Novitch, B.G. (2015). Notch Activity Modulates the Responsiveness of Neural Progenitors to Sonic Hedgehog Signaling. Developmental Cell 33, 373-387.

Miquelajauregui, A., Kribakaran, S., Mostany, R., Badaloni, A., Consalez, G.G., and Portera-Cailliau, C. (2015). Layer 4 pyramidal neurons exhibit robust dendritic spine plasticity in vivo after input deprivation. Journal of Neuroscience 35, 7287-7294.

Berent-Maoz, B., Montecino-Rodriguez, E., Fice, M., Casero, D., Seet, C.S., Crooks, G.M., Lowry, W., and Dorshkind, K. (2015). The expansion of thymopoiesis in neonatal mice is dependent on expression of high mobility group a 2 protein (hmga2). PloS One 10, e0125414.

Li, Q., Loh, D.H., Kudo, T., Truong, D., Derakhshesh, M., Kaswan, Z.M., Ghiani, C.A., Tsoa, R., Cheng, Y., Sun, Y.E., et al. (2015). Circadian rhythm disruption in a mouse model of Rett syndrome circadian disruption in RTT. Neurobiology of Disease 77, 155-164.

McCracken, M.N., Vatakis, D.N., Dixit, D., McLaughlin, J., Zack, J.A., and Witte, O.N. (2015). Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging. The Journal of Clinical Investigation 125, 1815-1826.

Madsen, S.K., Zai, A., Pirnia, T., Arienzo, D., Zhan, L., Moody, T.D., Thompson, P.M., and Feusner, J.D. (2015). Cortical thickness and brain volumetric analysis in body dysmorphic disorder. Psychiatry Research 232, 115-122.

Hoban, M.D., Cost, G.J., Mendel, M.C., Romero, Z., Kaufman, M.L., Joglekar, A.V., Ho, M., Lumaquin, D., Gray, D., Lill, G.R., et al. (2015). Correction of the sickle-cell disease mutation in human hematopoietic stem/progenitor cells. Blood 125, 2597-604.

Romero, Z., Campo-Fernandez, B., Wherley, J., Kaufman, M.L., Urbinati, F., Cooper, A.R., Hoban, M.D., Baldwin, K.M., Lumaquin, D., Wang, X., et al. (2015). The human ankyrin 1 promoter insulator sustains gene expression in a beta-globin lentiviral vector in hematopoietic stem cells. Molecular Therapy Methods & Clinical Development 2, 15012.

Gholkar, A.A., Senese, S., Lo, Y.C., Capri, J., Deardorff, W.J., Dharmarajan, H., Contreras, E., Hodara, E., Whitelegge, J.P., Jackson, P.K., et al. (2015). Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis. Cell Cycle 14, 1116-1125.

Kwon, M.H., Zhang, J.Q., Schaenman, J.M., Cadeiras, M., Gjertson, D.W., Krystal, C.A., Laks, H., Ardehali, A., Deng, M.C., Shemin, R.J., et al. (2015). Characterization of ventricular assist device-mediated sensitization in the bridge-to-heart-transplantation patient. Journal of Thoracic and Cardiovascular Surgery 149, 1161-1166.

Xie, L.X., Williams, K.J., He, C.H., Weng, E., Khong, S., Rose, T.E., Kwon, O., Bensinger, S.J., Marbois, B.N., and Clarke, C.F. (2015). Resveratrol and para-coumarate serve as ring precursors for coenzyme Q biosynthesis. Journal of Lipid Research 56, 909-919.

Pentecost, M., Vashisht, A.A., Lester, T., Voros, T., Beaty, S.M., Park, A., Wang, Y.E., Yun, T.E., Freiberg, A.N., Wohlschlegel, J.A., et al. (2015). Evidence for ubiquitin-regulated nuclear and subnuclear trafficking among Paramyxovirinae matrix proteins. PLoS Pathogens 11, e1004739.

Pena, J.M., Carrillo, M.A., and Hallem, E.A. (2015). Variation in the susceptibility of Drosophila to different entomopathogenic nematodes. Infection and immunity 83, 1130-1138.

Chen, A.L., Kim, E.W., Toh, J.Y., Vashisht, A.A., Rashoff, A.Q., Van, C., Huang, A.S., Moon, A.S., Bell, H.N., Bentolila, L.A., et al. (2015). Novel components of the Toxoplasma inner membrane complex revealed by BioID. mBio 6, e02357-02314.

Dudani, J.S., Gossett, D.R., Tse, H.T., Lamm, R.J., Kulkarni, R.P., and Carlo, D.D. (2015). Rapid inertial solution exchange for enrichment and flow cytometric detection of microvesicles. Biomicrofluidics 9, 014112.

Prashad, S.L., Calvanese, V., Yao, C.Y., Kaiser, J., Wang, Y., Sasidharan, R., Crooks, G., Magnusson, M., and Mikkola, H.K. (2015). GPI-80 Defines Self-Renewal Ability in Hematopoietic Stem Cells during Human Development. Cell Stem Cell 16, 80-87.

Romay, M.C., Che, N., Becker, S.N., Pouldar, D., Hagopian, R., Xiao, X., Lusis, A.J., Berliner, J.A., and Civelek, M. (2015). Regulation of NF-kappaB signaling by oxidized glycerophospholipid and IL-1beta induced miRs-21-3p and -27a-5p in human aortic endothelial cells. Journal of Lipid Research 56, 38-50.

2014

Wong, D.M., Shen, Z., Owyang, K.E., and Martinez-Agosto, J.A. (2014). Insulin- and Warts-Dependent Regulation of Tracheal Plasticity Modulates Systemic Larval Growth during Hypoxia in Drosophila melanogaster. PloS One 9, e115297.

Pasque, V., Tchieu, J., Karnik, R., Uyeda, M., Sadhu Dimashkie, A., Case, D., Papp, B., Bonora, G., Patel, S., Ho, R., et al. (2014). X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency. Cell 159, 1681-1697.

Pastor, W.A., Stroud, H., Nee, K., Liu, W., Pezic, D., Manakov, S., Lee, S.A., Moissiard, G., Zamudio, N., Bourc’his, D., et al. (2014). MORC1 represses transposable elements in the mouse male germline. Nature Communications 5, 5795.

Patterson, M., Gaeta, X., Loo, K., Edwards, M., Smale, S., Cinkornpumin, J., Xie, Y., Listgarten, J., Azghadi, S., Douglass, S.M., et al. (2014). let-7 miRNAs can act through notch to regulate human gliogenesis. Stem Cell Reports 3, 758-773.

Xie, Y., Zhang, J., Lin, Y., Gaeta, X., Meng, X., Wisidagama, D.R., Cinkornpumin, J., Koehler, C.M., Malone, C.S., Teitell, M.A., et al. (2014). Defining the role of oxygen tension in human neural progenitor fate. Stem Cell Reports 3, 743-757.

Gluck, J.M., Delman, C., Chyu, J., MacLellan, W.R., Shemin, R.J., and Heydarkhan-Hagvall, S. (2014). Microenvironment influences vascular differentiation of murine cardiovascular progenitor cells. Journal of Biomedical Materials Research Part B, Applied Biomaterials 102, 1730-1739.

Demagny, H., Araki, T., and De Robertis, E.M. (2014). The tumor suppressor Smad4/DPC4 is regulated by phosphorylations that integrate FGF, Wnt, and TGF-beta signaling. Cell Reports 9, 688-700.

Gong, D., Wu, N.C., Xie, Y., Feng, J., Tong, L., Brulois, K.F., Luan, H., Du, Y., Jung, J.U., Wang, C.Y., et al. (2014). Kaposi’s sarcoma-associated herpesvirus ORF18 and ORF30 are essential for late gene expression during lytic replication. Journal of Virology 88, 11369-11382.

Castelletto, M.L., Gang, S.S., Okubo, R.P., Tselikova, A.A., Nolan, T.J., Platzer, E.G., Lok, J.B., and Hallem, E.A. (2014). Diverse host-seeking behaviors of skin-penetrating nematodes. PLoS Pathogens 10, e1004305.

McVerry, B.T., Wong, M.C., Marsh, K.L., Temple, J.A., Marambio-Jones, C., Hoek, E.M., and Kaner, R.B. (2014). Scalable antifouling reverse osmosis membranes utilizing perfluorophenyl azide photochemistry. Macromolecular Rapid Communications 35, 1528-1533.

Wu, N.C., Young, A.P., Al-Mawsawi, L.Q., Olson, C.A., Feng, J., Qi, H., Luan, H.H., Li, X., Wu, T.T., and Sun, R. (2014). High-throughput identification of loss-of-function mutations for anti-interferon activity in the influenza A virus NS segment. Journal of Virology 88, 10157-10164.

Zhen, A., Krutzik, S.R., Levin, B.R., Kasparian, S., Zack, J.A., and Kitchen, S.G. (2014). CD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infection. Journal of Virology 88, 9934-9946.

Eshraghi, A., Dixon, S.D., Tamilselvam, B., Kim, E.J., Gargi, A., Kulik, J.C., Damoiseaux, R., Blanke, S.R., and Bradley, K.A. (2014). Cytolethal distending toxins require components of the ER-associated degradation pathway for host cell entry. PLoS Pathogens 10, e1004295.

Clark, P.M., Flores, G., Evdokimov, N.M., McCracken, M.N., Chai, T., Nair-Gill, E., O’Mahony, F., Beaven, S.W., Faull, K.F., Phelps, M.E., et al. (2014). Positron emission tomography probe demonstrates a striking concentration of ribose salvage in the liver. Proceedings of the National Academy of Sciences of the United States of America 111, E2866-2874.

Quick-Cleveland, J., Jacob, J.P., Weitz, S.H., Shoffner, G., Senturia, R., and Guo, F. (2014). The DGCR8 RNA-binding heme domain recognizes primary microRNAs by clamping the hairpin. Cell Reports 7, 1994-2005.

Kim, W.S., Zhu, Y., Deng, Q., Chin, C.J., He, C.B., Grieco, A.J., Dravid, G.G., Parekh, C., Hollis, R.P., Lane, T.F., et al. (2014). Erythropoiesis from human embryonic stem cells through erythropoietin-independent AKT signaling. Stem Cells 32, 1503-1514.

Montecino-Rodriguez, E., Li, K., Fice, M., and Dorshkind, K. (2014). Murine B-1 B cell progenitors initiate B-acute lymphoblastic leukemia with features of high-risk disease. Journal of Immunology192, 5171-5178.

Wu, N.C., De La Cruz, J., Al-Mawsawi, L.Q., Olson, C.A., Qi, H., Luan, H.H., Nguyen, N., Du, Y., Le, S., Wu, T.T., et al. (2014). HIV-1 quasispecies delineation by tag linkage deep sequencing. PloS one 9, e97505.

Wu, N.C., Young, A.P., Al-Mawsawi, L.Q., Olson, C.A., Feng, J., Qi, H., Chen, S.H., Lu, I.H., Lin, C.Y., Chin, R.G., Luan, H.H., et al. (2014). High-throughput profiling of influenza A virus hemagglutinin gene at single-nucleotide resolution. Scientific Reports 4, 4942.

O’Donnell, K.C., Lulla, A., Stahl, M.C., Wheat, N.D., Bronstein, J.M., and Sagasti, A. (2014). Axon degeneration and PGC-1alpha-mediated protection in a zebrafish model of alpha-synuclein toxicity. Disease Models & Mechanisms 7, 571-582.

Pecot, M.Y., Chen, Y., Akin, O., Chen, Z., Tsui, C.Y., and Zipursky, S.L. (2014). Sequential axon-derived signals couple target survival and layer specificity in the Drosophila visual system. Neuron 82, 320-333.

Gkountela, S., Li, Z., Chin, C.J., Lee, S.A., and Clark, A.T. (2014). PRMT5 is required for human embryonic stem cell proliferation but not pluripotency. Stem Cell Reviews 10, 230-239.

Rigueur, D., Brugger, S., Anbarchian, T., Kim, J.K., Lee, Y.J., and Lyons, K. (2014). The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development. Journal of Bone and Mineral Research 30, 733-741.

Nakashima, Y., Yanez, D.A., Touma, M., Nakano, H., Jaroszewicz, A., Jordan, M.C., Pellegrini, M., Roos, K.P., and Nakano, A. (2014). Nkx2-5 suppresses the proliferation of atrial myocytes and conduction system. Circulation Research 114, 1103-1113.

Li, Z., Yu, J., Hosohama, L., Nee, K., Gkountela, S., Chaudhari, S., Cass, A.A., Xiao, X., and Clark, A.T. (2014). The Sm protein methyltransferase PRMT5 is not required for primordial germ cell specification in mice. EMBO Journal 34, 748-758.

Nathanson, D.A., Armijo, A.L., Tom, M., Li, Z., Dimitrova, E., Austin, W.R., Nomme, J., Campbell, D.O., Ta, L., Le, T.M., et al. (2014). Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication. Journal of Experimental Medicine 211, 473-486.

Tan, A.P., Dudani, J.S., Arshi, A., Lee, R.J., Tse, H.T., Gossett, D.R., and Di Carlo, D. (2014). Continuous-flow cytomorphological staining and analysis. Lab on a Chip 14, 522-531.

Dudani, J.S., Go, D.E., Gossett, D.R., Tan, A.P., and Di Carlo, D. (2014). Mediating millisecond reaction time around particles and cells. Analytical Chemistry 86, 1502-1510.

Lawal, H.O., Terrell, A., Lam, H.A., Djapri, C., Jang, J., Hadi, R., Roberts, L., Shahi, V., Chou, M.T., Biedermann, T., et al. (2014). Drosophila modifier screens to identify novel neuropsychiatric drugs including aminergic agents for the possible treatment of Parkinson’s disease and depression. Molecular Psychiatry 19, 235-242.

Weaver, W.M., Tseng, P., Kunze, A., Masaeli, M., Chung, A.J., Dudani, J.S., Kittur, H., Kulkarni, R.P., and Di Carlo, D. (2014). Advances in high-throughput single-cell microtechnologies. Current Opinion in Biotechnology 25, 114-123.

Chen, Y., Akin, O., Nern, A., Tsui, C.Y., Pecot, M.Y., and Zipursky, S.L. (2014). Cell-type-specific labeling of synapses in vivo through synaptic tagging with recombination. Neuron 81, 280-293.

Arakawa, C., Ng, R., Tan, S., Kim, S., Wu, B., and Lee, M. (2014). Photopolymerizable chitosan-collagen hydrogels for bone tissue engineering. Journal of Tissue Engineering and Regenerative Medicine.

Stroud, H., Do, T., Du, J., Zhong, X., Feng, S., Johnson, L., Patel, D.J., and Jacobsen, S.E. (2014). Non-CG methylation patterns shape the epigenetic landscape in Arabidopsis. Nature Structural & Molecular Biology 21, 64-72.

2013

Milde, F., Lauw, S., Koumoutsakos, P., and Iruela-Arispe, M.L. (2013). The mouse retina in 3D: quantification of vascular growth and remodeling. Integrative Biology 5, 1426-1438.

Shim, J., Mukherjee, T., Mondal, B.C., Liu, T., Young, G.C., Wijewarnasuriya, D.P., and Banerjee, U. (2013). Olfactory control of blood progenitor maintenance. Cell 155, 1141-1153.

Kim, S.G., Jung, J.B., Dixit, D., Rovner, R., Jr., Zack, J.A., Baldwin, G.C., and Vatakis, D.N. (2013). Cocaine exposure enhances permissiveness of quiescent T cells to HIV infection. Journal of Leukocyte Biology 94, 835-843.

Turlo, K.A., Scapa, J., Bagher, P., Jones, A.W., Feil, R., Korthuis, R.J., Segal, S.S., and Iruela-Arispe, M.L. (2013). beta1-integrin is essential for vasoregulation and smooth muscle survival in vivo. Arteriosclerosis, Thrombosis, and Vascular Biology 33, 2325-2335.

Nixon, C.C., Vatakis, D.N., Reichelderfer, S.N., Dixit, D., Kim, S.G., Uittenbogaart, C.H., and Zack, J.A. (2013). HIV-1 infection of hematopoietic progenitor cells in vivo in humanized mice. Blood 122, 2195-2204.

Gluck, J. M.; Chyu, J.; Delman, C.; Heydarkhan-Hagvall, S.; MacLellan, W. R.; Shemin, R. J. Hyaluronan-Based Three-Dimensional Microenvironment Potently Induces Cardiovascular Progenitor Cell Populations. ISRN Tissue Eng 2013, 2013, 752620.

Jiang, Z.K., Johnson, M., Moughon, D.L., Kuo, J., Sato, M., and Wu, L. (2013). Rapamycin enhances adenovirus-mediated cancer imaging and therapy in pre-immunized murine hosts. PloS One 8, e73650.

Barkhordarian, A., Pellionisz, P., Dousti, M., Lam, V., Gleason, L., Dousti, M., Moura, J., and Chiappelli, F. (2013). Assessment of risk of bias in translational science. Journal of Translational Medicine 11, 184.

Hall-Glenn, F., De Young, R.A., Huang, B.L., van Handel, B., Hofmann, J.J., Chen, T.T., Choi, A., Ong, J.R., Benya, P.D., Mikkola, H., et al. (2012). CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. PloS One 7, e30562.

Goddard, L.M., Ton, A.N., Org, T., Mikkola, H.K., and Iruela-Arispe, M.L. (2013). Selective suppression of endothelial cytokine production by progesterone receptor. Vascular Pharmacology 59, 36-43.

Tran, C.M., Fujita, N., Huang, B.L., Ong, J.R., Lyons, K.M., Shapiro, I.M., and Risbud, M.V. (2013). Hypoxia-inducible factor (HIF)-1alpha and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1alpha level and transcriptional activity. Journal of Biological Chemistry 288, 12654-12666.

Akhavan, D., Pourzia, A.L., Nourian, A.A., Williams, K.J., Nathanson, D., Babic, I., Villa, G.R., Tanaka, K., Nael, A., Yang, H., et al. (2013). De-repression of PDGFRbeta transcription promotes acquired resistance to EGFR tyrosine kinase inhibitors in glioblastoma patients. Cancer Discovery 3, 534-547.

Chu, D., Ren, S., Hu, S., Wang, W.G., Subramanian, A., Contreras, D., Kanagavel, V., Chung, E., Ko, J., Amirtham Jacob Appadorai, R.S., et al. (2013). Systematic analysis of enhancer and critical cis-acting RNA elements in the protein-encoding region of the hepatitis C virus genome. Journal of Virology 87, 5678-5696.

Williams, K.J., Argus, J.P., Zhu, Y., Wilks, M.Q., Marbois, B.N., York, A.G., Kidani, Y., Pourzia, A.L., Akhavan, D., Lisiero, D.N., et al. (2013). An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity. Cancer Research 73, 2850-2862.

Nakatsu, M.N., Vartanyan, L., Vu, D.M., Ng, M.Y., Li, X., and Deng, S.X. (2013). Preferential biological processes in the human limbus by differential gene profiling. PloS One 8, e61833.

Vincent, J.J., Huang, Y., Chen, P.Y., Feng, S., Calvopina, J.H., Nee, K., Lee, S.A., Le, T., Yoon, A.J., Faull, K., et al. (2013). Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells. Cell Stem Cell 12, 470-478.

Varshney, G.K., Lu, J., Gildea, D.E., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D., Pho, N.H., Casero, D., Hirase, T., et al. (2013). A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome Research 23, 727-735.

Sun, Y., Hu, Z., Goeb, Y., and Dreier, L. (2013). The F-box protein MEC-15 (FBXW9) promotes synaptic transmission in GABAergic motor neurons in C. elegans. PloS One 8, e59132.

Dec17 Zhang, X., Guo, H., Jin, L., Czornyj, E., Hodes, A., Hui, W.H., Nieh, A.W., Miller, J.F., and Zhou, Z.H. (2013). A new topology of the HK97-like fold revealed in Bordetella bacteriophage by cryoEM at 3.5 A resolution. eLife 2, e01299.

de Resende, M.F., Vieira, S., Chinen, L.T., Chiappelli, F., da Fonseca, F.P., Guimaraes, G.C., Soares, F.A., Neves, I., Pagotty, S., Pellionisz, P.A., et al. (2013). Prognostication of prostate cancer based on TOP2A protein and gene assessment: TOP2A in prostate cancer. Journal of Translational Medicine 11, 36.

Garcia, A.J., Tom, C., Guemes, M., Polanco, G., Mayorga, M.E., Wend, K., Miranda-Carboni, G.A., and Krum, S.A. (2013). ERalpha signaling regulates MMP3 expression to induce FasL cleavage and osteoclast apoptosis. Journal of Bone and Mineral Research 28, 283-290.

Palanca, A.M., Lee, S.L., Yee, L.E., Joe-Wong, C., Trinh le, A., Hiroyasu, E., Husain, M., Fraser, S.E., Pellegrini, M., and Sagasti, A. (2013). New transgenic reporters identify somatosensory neuron subtypes in larval zebrafish. Developmental Neurobiology 73, 152-167.

Tran, T., Andersen, R., Sherman, S.P., and Pyle, A.D. (2013). Insights into skeletal muscle development and applications in regenerative medicine. International Review of Cell and Molecular Biology 300, 51-83.

2012

Schwartz, A.R., Ortiz, I., Maymon, M., Herbold, C.W., Fujishige, N.A., Vijanderan, J.A., Villella, W., Hanamoto, K., Diener, A., Sanders, E.R., et al. (2013). Bacillus simplex—A Little Known PGPB with Anti-Fungal Activity—Alters Pea Legume Root Architecture and Nodule Morphology When Coinoculated with Rhizobium leguminosarum bv. viciae. Agronomy 3, 595-620.

Gomez, F., Monsalve, G.C., Tse, V., Saiki, R., Weng, E., Lee, L., Srinivasan, C., Frand, A.R., and Clarke, C.F. (2012). Delayed accumulation of intestinal coliform bacteria enhances life span and stress resistance in Caenorhabditis elegans fed respiratory deficient E. coli. BMC Microbiology 12, 300.

Olson, C.A., Nie, J., Diep, J., Al-Shyoukh, I., Takahashi, T.T., Al-Mawsawi, L.Q., Bolin, J.M., Elwell, A.L., Swanson, S., Stewart, R., et al. (2012). Single-round, multiplexed antibody mimetic design through mRNA display. Angewandte Chemie 51, 12449-12453.

Rhee, K.D., Yu, J., Zhao, C.Y., Fan, G., and Yang, X.J. (2012). Dnmt1-dependent DNA methylation is essential for photoreceptor terminal differentiation and retinal neuron survival. Cell Death & Disease 3, e427.

Biering, S.B., Huang, A., Vu, A.T., Robinson, L.R., Bradel-Tretheway, B., Choi, E., Lee, B., and Aguilar, H.C. (2012). N-Glycans on the Nipah virus attachment glycoprotein modulate fusion and viral entry as they protect against antibody neutralization. Journal of Virology 86, 11991-12002.

Marshall, J.L., Chou, E., Oh, J., Kwok, A., Burkin, D.J., and Crosbie-Watson, R.H. (2012). Dystrophin and utrophin expression require sarcospan: loss of alpha7 integrin exacerbates a newly discovered muscle phenotype in sarcospan-null mice. Human Molecular Genetics 21, 4378-4393.

Nsair, A., Schenke-Layland, K., Van Handel, B., Evseenko, D., Kahn, M., Zhao, P., Mendelis, J., Heydarkhan, S., Awaji, O., Vottler, M., Geist, S., Chyu, J., et al. (2012). Characterization and therapeutic potential of induced pluripotent stem cell-derived cardiovascular progenitor cells. PloS One 7, e45603.

Hill, R., Li, Y., Tran, L.M., Dry, S., Calvopina, J.H., Garcia, A., Kim, C., Wang, Y., Donahue, T.R., Herschman, H.R., et al. (2012). Cell intrinsic role of COX-2 in pancreatic cancer development. Molecular Cancer Therapeutics 11, 2127-2137.

Gossett, D. R.; Tse, H. T. K.; Dudani, J. S.; Goda, K.; Woods, T. A.; Graves, S. W.; Di Carlo, D. Inertial Manipulation and Transfer of Microparticles across Laminar Fluid Streams. Small 2012, 8 (17), 2757–2764.

Bhatt, D.M., Pandya-Jones, A., Tong, A.J., Barozzi, I., Lissner, M.M., Natoli, G., Black, D.L., and Smale, S.T. (2012). Transcript dynamics of proinflammatory genes revealed by sequence analysis of subcellular RNA fractions. Cell 150, 279-290.

Ch’ng, T.H., Uzgil, B., Lin, P., Avliyakulov, N.K., O’Dell, T.J., and Martin, K.C. (2012). Activity-dependent transport of the transcriptional coactivator CRTC1 from synapse to nucleus. Cell 150, 207-221.

Meloty-Kapella, L., Shergill, B., Kuon, J., Botvinick, E., and Weinmaster, G. (2012). Notch ligand endocytosis generates mechanical pulling force dependent on dynamin, epsins, and actin. Developmental Cell 22, 1299-1312.

Arboleda, V.A., Lee, H., Parnaik, R., Fleming, A., Banerjee, A., Ferraz-de-Souza, B., Delot, E.C., Rodriguez-Fernandez, I.A., Braslavsky, D., Bergada, I., et al. (2012). Mutations in the PCNA-binding domain of CDKN1C cause IMAGe syndrome. Nature Genetics 44, 788-792.

Macey, P.M., Wu, P., Kumar, R., Ogren, J.A., Richardson, H.L., Woo, M.A., and Harper, R.M. (2012). Differential responses of the insular cortex gyri to autonomic challenges. Autonomic Neuroscience : Basic & Clinical 168, 72-81.

Lamkin, D.M., Sloan, E.K., Patel, A.J., Chiang, B.S., Pimentel, M.A., Ma, J.C., Arevalo, J.M., Morizono, K., and Cole, S.W. (2012). Chronic stress enhances progression of acute lymphoblastic leukemia via beta-adrenergic signaling. Brain, Behavior, and Immunity 26, 635-641.

Monclus, R., Cook, T., and Blumstein, D.T. (2012). Masculinized female yellow-bellied marmots initiate more social interactions. Biology Letters 8, 208-210.

Donahue, T.R., Tran, L.M., Hill, R., Li, Y., Kovochich, A., Calvopina, J.H., Patel, S.G., Wu, N., Hindoyan, A., Farrell, J.J., et al. (2012). Integrative survival-based molecular profiling of human pancreatic cancer. Clinical Cancer Research 18, 1352-1363.

Hall-Glenn, F., Aivazi, A., Akopyan, L., Ong, J.R., Baxter, R.R., Benya, P.D., Goldschmeding, R., van Nieuwenhoven, F.A., Hunziker, E.B., and Lyons, K.M. (2012). CCN2/CTGF is required for matrix organization and to protect growth plate chondrocytes from cellular stress. Journal of Cell Communication and Signaling 7, 219-230.

Birukova, A.A., Lee, S., Starosta, V., Wu, T., Ho, T., Kim, J., Berliner, J.A., and Birukov, K.G. (2012). A role for VEGFR2 activation in endothelial responses caused by barrier disruptive OxPAPC concentrations. PloS One 7, e30957.

Choe, U.J., Sun, V.Z., Tan, J.K., and Kamei, D.T. (2012). Self-assembled polypeptide and polypeptide hybrid vesicles: from synthesis to application. Topics in Current Chemistry 310, 117-134.

Cruz-Martin, A., Crespo, M., and Portera-Cailliau, C. (2012). Glutamate induces the elongation of early dendritic protrusions via mGluRs in wild type mice, but not in fragile X mice. PloS One 7, e32446.

Mukherjee, T., Choi, I., and Banerjee, U. (2012). Genetic analysis of fibroblast growth factor signaling in the Drosophila eye. G3 2, 23-28.

2011

Patterson, M., Chan, D.N., Ha, I., Case, D., Cui, Y., Van Handel, B., Mikkola, H.K., and Lowry, W.E. (2011). Defining the nature of human pluripotent stem cell progeny. Cell Research 22, 178-193.

Roberts, A.C., Reichl, J., Song, M.Y., Dearinger, A.D., Moridzadeh, N., Lu, E.D., Pearce, K., Esdin, J., and Glanzman, D.L. (2011). Habituation of the C-start response in larval zebrafish exhibits several distinct phases and sensitivity to NMDA receptor blockade. PloS One 6, e29132.

Brown, J.A., Terashima, K.H., Burggren, A.C., Ercoli, L.M., Miller, K.J., Small, G.W., and Bookheimer, S.Y. (2011). Brain network local interconnectivity loss in aging APOE-4 allele carriers. Proceedings of the National Academy of Sciences of the United States of America 108, 20760-20765.

Vincent, J.J., Li, Z., Lee, S.A., Liu, X., Etter, M.O., Diaz-Perez, S.V., Taylor, S.K., Gkountela, S., Lindgren, A.G., and Clark, A.T. (2011). Single cell analysis facilitates staging of Blimp1-dependent primordial germ cells derived from mouse embryonic stem cells. PloS One 6, e28960.

Alva, J.A., Lee, G.E., Escobar, E.E., and Pyle, A.D. (2011). Phosphatase and tensin homolog regulates the pluripotent state and lineage fate choice in human embryonic stem cells. Stem Cells (Dayton, Ohio) 29, 1952-1962.

Guo, H., Tse, L.V., Nieh, A.W., Czornyj, E., Williams, S., Oukil, S., Liu, V.B., and Miller, J.F. (2011). Target site recognition by a diversity-generating retroelement. PLoS Genetics 7, e1002414.

Santana, S. E.; Dial, T. O.; Eiting, T. P.; Alfaro, M. E. Roosting Ecology and the Evolution of Pelage Markings in Bats. PLoS One 2011, 6 (10), e25845.

Estrada, K.D., Retting, K.N., Chin, A.M., and Lyons, K.M. (2011). Smad6 is essential to limit BMP signaling during cartilage development. Journal of Bone and Mineral Research 26, 2498-2510.

Guo, D., Reinitz, F., Youssef, M., Hong, C., Nathanson, D., Akhavan, D., Kuga, D., Amzajerdi, A.N., Soto, H., Zhu, S., et al. (2011). An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway. Cancer Discovery 1, 442-456.

Lee, S., Salwinski, L., Zhang, C., Chu, D., Sampankanpanich, C., Reyes, N.A., Vangeloff, A., Xing, F., Li, X., Wu, T.T., et al. (2011). An integrated approach to elucidate the intra-viral and viral-cellular protein interaction networks of a gamma-herpesvirus. PLoS Pathogens 7, e1002297.

Takashima, S., Adams, K.L., Ortiz, P.A., Ying, C.T., Moridzadeh, R., Younossi-Hartenstein, A., and Hartenstein, V. (2011). Development of the Drosophila entero-endocrine lineage and its specification by the Notch signaling pathway. Developmental Biology 353, 161-172.

Fahey, L.M., Wilson, E.B., Elsaesser, H., Fistonich, C.D., McGavern, D.B., and Brooks, D.G. (2011). Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells. Journal of Experimental Medicine 208, 987-999.

Liu, A., Fong, A., Becket, E., Yuan, J., Tamae, C., Medrano, L., Maiz, M., Wahba, C., Lee, C., Lee, K., et al. (2011). Selective advantage of resistant strains at trace levels of antibiotics: a simple and ultrasensitive color test for detection of antibiotics and genotoxic agents. Antimicrobial Agents and Chemotherapy 55, 1204-1210.

Ziegler, M.D., Hsu, D., Takeoka, A., Zhong, H., Ramon-Cueto, A., Phelps, P.E., Roy, R.R., and Edgerton, V.R. (2011). Further evidence of olfactory ensheathing glia facilitating axonal regeneration after a complete spinal cord transection. Experimental Neurology 229, 109-119.

Tsang, E.J., Arakawa, C.K., Zuk, P.A., and Wu, B.M. (2011). Osteoblast interactions within a biomimetic apatite microenvironment. Annals of Biomedical Engineering 39, 1186-1200.

Hill, S., Hirano, K., Shmanai, V.V., Marbois, B.N., Vidovic, D., Bekish, A.V., Kay, B., Tse, V., Fine, J., Clarke, C.F., et al. (2011). Isotope-reinforced polyunsaturated fatty acids protect yeast cells from oxidative stress. Free radical biology & medicine 50, 130-138.

2010

Sinenko, S.A., Hung, T., Moroz, T., Tran, Q.M., Sidhu, S., Cheney, M.D., Speck, N.A., and Banerjee, U. (2010). Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model. Blood 116, 4612-4620.

Zovein, A.C., Turlo, K.A., Ponec, R.M., Lynch, M.R., Chen, K.C., Hofmann, J.J., Cox, T.C., Gasson, J.C., and Iruela-Arispe, M.L. (2010). Vascular remodeling of the vitelline artery initiates extravascular emergence of hematopoietic clusters. Blood 116, 3435-3444.

Kabututu, Z.P., Thayer, M., Melehani, J.H., and Hill, K.L. (2010). CMF70 is a subunit of the dynein regulatory complex. Journal of Cell Science 123, 3587-3595.

Ngo, K.T., Wang, J., Junker, M., Kriz, S., Vo, G., Asem, B., Olson, J.M., Banerjee, U., and Hartenstein, V. (2010). Concomitant requirement for Notch and Jak/Stat signaling during neuro-epithelial differentiation in the Drosophila optic lobe. Developmental biology 346, 284-295.

Tchieu, J., Kuoy, E., Chin, M.H., Trinh, H., Patterson, M., Sherman, S.P., Aimiuwu, O., Lindgren, A., Hakimian, S., Zack, J.A., et al. (2010). Female human iPSCs retain an inactive X chromosome. Cell Stem Cell 7, 329-342.

Hill, R., Calvopina, J.H., Kim, C., Wang, Y., Dawson, D.W., Donahue, T.R., Dry, S., and Wu, H. (2010). PTEN loss accelerates KrasG12D-induced pancreatic cancer development. Cancer Research 70, 7114-7124.

Sloan, E.K., Priceman, S.J., Cox, B.F., Yu, S., Pimentel, M.A., Tangkanangnukul, V., Arevalo, J.M., Morizono, K., Karanikolas, B.D., Wu, L., et al. (2010). The sympathetic nervous system induces a metastatic switch in primary breast cancer. Cancer Research 70, 7042-7052.

Ramey, J.D., Villareal, V.A., Ng, C., Ward, S.C., Xiong, J.P., Clubb, R.T., and Bradley, K.A. (2010). Anthrax toxin receptor 1/tumor endothelial marker 8: mutation of conserved inserted domain residues overrides cytosolic control of protective antigen binding. Biochemistry 49, 7403-7410.

Yavari, A., Nagaraj, R., Owusu-Ansah, E., Folick, A., Ngo, K., Hillman, T., Call, G., Rohatgi, R., Scott, M.P., and Banerjee, U. (2010). Role of lipid metabolism in smoothened derepression in hedgehog signaling. Developmental Cell 19, 54-65.

Cruz-Martin, A., Crespo, M., and Portera-Cailliau, C. (2010). Delayed stabilization of dendritic spines in fragile X mice. Journal of Neuroscience 30, 7793-7803.

Lee, R., Chang, S.Y., Trinh, H., Tu, Y., White, A.C., Davies, B.S., Bergo, M.O., Fong, L.G., Lowry, W.E., and Young, S.G. (2010). Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes. Human Molecular Genetics 19, 1603-1617.

Liu, A., Tran, L., Becket, E., Lee, K., Chinn, L., Park, E., Tran, K., and Miller, J.H. (2010). Antibiotic sensitivity profiles determined with an Escherichia coli gene knockout collection: generating an antibiotic bar code. Antimicrobial Agents and Chemotherapy 54, 1393-1403.

2009

Tarcic, G., Boguslavsky, S.K., Wakim, J., Kiuchi, T., Liu, A., Reinitz, F., Nathanson, D., Takahashi, T., Mischel, P.S., Ng, T., et al. (2009). An unbiased screen identifies DEP-1 tumor suppressor as a phosphatase controlling EGFR endocytosis. Current Biology : CB 19, 1788-1798.

Ralston, K.S., Kabututu, Z.P., Melehani, J.H., Oberholzer, M., and Hill, K.L. (2009). The Trypanosoma brucei flagellum: moving parasites in new directions. Annual Review of Microbiology 63, 335-362.

Kumar, R., Lee, K., Macey, P.M., Woo, M.A., and Harper, R.M. (2009). Mammillary body and fornix injury in congenital central hypoventilation syndrome. Pediatric Research 66, 429-434.

Fulcher, J.A., Chang, M.H., Wang, S., Almazan, T., Hashimi, S.T., Eriksson, A.U., Wen, X., Pang, M., Baum, L.G., Singh, R.R., et al. (2009). Galectin-1 co-clusters CD43/CD45 on dendritic cells and induces cell activation and migration through Syk and protein kinase C signaling. Journal of Biological Chemistry 284, 26860-26870.

Golshani, P., Goncalves, J.T., Khoshkhoo, S., Mostany, R., Smirnakis, S., and Portera-Cailliau, C. (2009). Internally mediated developmental desynchronization of neocortical network activity. Journal of Neuroscience 29, 10890-10899.

Evans, C.J., Olson, J.M., Ngo, K.T., Kim, E., Lee, N.E., Kuoy, E., Patananan, A.N., Sitz, D., Tran, P., Do, M.T., et al. (2009). G-TRACE: rapid Gal4-based cell lineage analysis in Drosophila. Nature Methods 6, 603-605.

Hashimi, S.T., Fulcher, J.A., Chang, M.H., Gov, L., Wang, S., and Lee, B. (2009). MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiation. Blood 114, 404-414.

Avagyan, H., Goldenson, B., Tse, E., Masoumi, A., Porter, V., Wiedau-Pazos, M., Sayre, J., Ong, R., Mahanian, M., Koo, P., et al. (2009). Immune blood biomarkers of Alzheimer disease patients. Journal of Neuroimmunology 210, 67-72.

Zaghi, J., Goldenson, B., Inayathullah, M., Lossinsky, A.S., Masoumi, A., Avagyan, H., Mahanian, M., Bernas, M., Weinand, M., Rosenthal, M.J., et al. (2009). Alzheimer disease macrophages shuttle amyloid-beta from neurons to vessels, contributing to amyloid angiopathy. Acta Neuropathologica 117, 111-124.

Masoumi, A., Goldenson, B., Ghirmai, S., Avagyan, H., Zaghi, J., Abel, K., Zheng, X., Espinosa-Jeffrey, A., Mahanian, M., Liu, P.T., et al. (2009). 1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer’s disease patients. Journal of Alzheimer’s Disease 17, 703-717.

2008

Miller, J.E., Spiteri, E., Condro, M.C., Dosumu-Johnson, R.T., Geschwind, D.H., and White, S.A. (2008). Birdsong decreases protein levels of FoxP2, a molecule required for human speech. Journal of Neurophysiology 100, 2015-2025.

Tamae, C., Liu, A., Kim, K., Sitz, D., Hong, J., Becket, E., Bui, A., Solaimani, P., Tran, K.P., Yang, H., et al. (2008). Determination of antibiotic hypersensitivity among 4,000 single-gene-knockout mutants of Escherichia coli. Journal of Bacteriology 190, 5981-5988.