Minor in Biomedical Research – Student Publications

Students in the Minor in Biomedical Research work on real research projects that are potentially publishable. There are currently 218 publications in peer-reviewed journals with one or more of our students or alumni as co-authors.

See here for a list of student authors.

A list of all 218 publications can be found here.

Lists of publications by year can be found below.

2008

Miller, J.E., Spiteri, E., Condro, M.C., Dosumu-Johnson, R.T., Geschwind, D.H., and White, S.A. (2008). Birdsong decreases protein levels of FoxP2, a molecule required for human speech. Journal of neurophysiology 100, 2015-2025.

Tamae, C., Liu, A., Kim, K., Sitz, D., Hong, J., Becket, E., Bui, A., Solaimani, P., Tran, K.P., Yang, H., et al. (2008). Determination of antibiotic hypersensitivity among 4,000 single-gene-knockout mutants of Escherichia coli. Journal of bacteriology 190, 5981-5988.

2009

Avagyan, H., Goldenson, B., Tse, E., Masoumi, A., Porter, V., Wiedau-Pazos, M., Sayre, J., Ong, R., Mahanian, M., Koo, P., et al. (2009). Immune blood biomarkers of Alzheimer disease patients. Journal of neuroimmunology 210, 67-72.

Evans, C.J., Olson, J.M., Ngo, K.T., Kim, E., Lee, N.E., Kuoy, E., Patananan, A.N., Sitz, D., Tran, P., Do, M.T., et al. (2009). G-TRACE: rapid Gal4-based cell lineage analysis in Drosophila. Nature methods 6, 603-605.

Fulcher, J.A., Chang, M.H., Wang, S., Almazan, T., Hashimi, S.T., Eriksson, A.U., Wen, X., Pang, M., Baum, L.G., Singh, R.R., et al. (2009). Galectin-1 co-clusters CD43/CD45 on dendritic cells and induces cell activation and migration through Syk and protein kinase C signaling. The Journal of biological chemistry 284, 26860-26870.

Golshani, P., Goncalves, J.T., Khoshkhoo, S., Mostany, R., Smirnakis, S., and Portera-Cailliau, C. (2009). Internally mediated developmental desynchronization of neocortical network activity. The Journal of neuroscience : the official journal of the Society for Neuroscience 29, 10890-10899.

Hashimi, S.T., Fulcher, J.A., Chang, M.H., Gov, L., Wang, S., and Lee, B. (2009). MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiation. Blood 114, 404-414.

Kumar, R., Lee, K., Macey, P.M., Woo, M.A., and Harper, R.M. (2009). Mammillary body and fornix injury in congenital central hypoventilation syndrome. Pediatric research 66, 429-434.

Masoumi, A., Goldenson, B., Ghirmai, S., Avagyan, H., Zaghi, J., Abel, K., Zheng, X., Espinosa-Jeffrey, A., Mahanian, M., Liu, P.T., et al. (2009). 1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients. Journal of Alzheimer's disease : JAD 17, 703-717.

Ralston, K.S., Kabututu, Z.P., Melehani, J.H., Oberholzer, M., and Hill, K.L. (2009). The Trypanosoma brucei flagellum: moving parasites in new directions. Annual review of microbiology 63, 335-362.

Tarcic, G., Boguslavsky, S.K., Wakim, J., Kiuchi, T., Liu, A., Reinitz, F., Nathanson, D., Takahashi, T., Mischel, P.S., Ng, T., et al. (2009). An unbiased screen identifies DEP-1 tumor suppressor as a phosphatase controlling EGFR endocytosis. Current biology : CB 19, 1788-1798.

Zaghi, J., Goldenson, B., Inayathullah, M., Lossinsky, A.S., Masoumi, A., Avagyan, H., Mahanian, M., Bernas, M., Weinand, M., Rosenthal, M.J., et al. (2009). Alzheimer disease macrophages shuttle amyloid-beta from neurons to vessels, contributing to amyloid angiopathy. Acta neuropathologica 117, 111-124.

2010

Cruz-Martin, A., Crespo, M., and Portera-Cailliau, C. (2010). Delayed stabilization of dendritic spines in fragile X mice. The Journal of neuroscience : the official journal of the Society for Neuroscience 30, 7793-7803.

Hill, R., Calvopina, J.H., Kim, C., Wang, Y., Dawson, D.W., Donahue, T.R., Dry, S., and Wu, H. (2010). PTEN loss accelerates KrasG12D-induced pancreatic cancer development. Cancer research 70, 7114-7124.

Kabututu, Z.P., Thayer, M., Melehani, J.H., and Hill, K.L. (2010). CMF70 is a subunit of the dynein regulatory complex. Journal of cell science 123, 3587-3595.

Lee, R., Chang, S.Y., Trinh, H., Tu, Y., White, A.C., Davies, B.S., Bergo, M.O., Fong, L.G., Lowry, W.E., and Young, S.G. (2010). Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes. Human molecular genetics 19, 1603-1617.

Liu, A., Tran, L., Becket, E., Lee, K., Chinn, L., Park, E., Tran, K., and Miller, J.H. (2010). Antibiotic sensitivity profiles determined with an Escherichia coli gene knockout collection: generating an antibiotic bar code. Antimicrobial agents and chemotherapy 54, 1393-1403.

Ngo, K.T., Wang, J., Junker, M., Kriz, S., Vo, G., Asem, B., Olson, J.M., Banerjee, U., and Hartenstein, V. (2010). Concomitant requirement for Notch and Jak/Stat signaling during neuro-epithelial differentiation in the Drosophila optic lobe. Developmental biology 346, 284-295.

Ramey, J.D., Villareal, V.A., Ng, C., Ward, S.C., Xiong, J.P., Clubb, R.T., and Bradley, K.A. (2010). Anthrax toxin receptor 1/tumor endothelial marker 8: mutation of conserved inserted domain residues overrides cytosolic control of protective antigen binding. Biochemistry 49, 7403-7410.

Sinenko, S.A., Hung, T., Moroz, T., Tran, Q.M., Sidhu, S., Cheney, M.D., Speck, N.A., and Banerjee, U. (2010). Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model. Blood 116, 4612-4620.

Sloan, E.K., Priceman, S.J., Cox, B.F., Yu, S., Pimentel, M.A., Tangkanangnukul, V., Arevalo, J.M., Morizono, K., Karanikolas, B.D., Wu, L., et al. (2010). The sympathetic nervous system induces a metastatic switch in primary breast cancer. Cancer research 70, 7042-7052.

Tchieu, J., Kuoy, E., Chin, M.H., Trinh, H., Patterson, M., Sherman, S.P., Aimiuwu, O., Lindgren, A., Hakimian, S., Zack, J.A., et al. (2010). Female human iPSCs retain an inactive X chromosome. Cell stem cell 7, 329-342.

Yavari, A., Nagaraj, R., Owusu-Ansah, E., Folick, A., Ngo, K., Hillman, T., Call, G., Rohatgi, R., Scott, M.P., and Banerjee, U. (2010). Role of lipid metabolism in smoothened derepression in hedgehog signaling. Developmental cell 19, 54-65.

Zovein, A.C., Turlo, K.A., Ponec, R.M., Lynch, M.R., Chen, K.C., Hofmann, J.J., Cox, T.C., Gasson, J.C., and Iruela-Arispe, M.L. (2010). Vascular remodeling of the vitelline artery initiates extravascular emergence of hematopoietic clusters. Blood 116, 3435-3444.

2011

Alva, J.A., Lee, G.E., Escobar, E.E., and Pyle, A.D. (2011). Phosphatase and tensin homolog regulates the pluripotent state and lineage fate choice in human embryonic stem cells. Stem cells (Dayton, Ohio) 29, 1952-1962.

Brown, J.A., Terashima, K.H., Burggren, A.C., Ercoli, L.M., Miller, K.J., Small, G.W., and Bookheimer, S.Y. (2011). Brain network local interconnectivity loss in aging APOE-4 allele carriers. Proceedings of the National Academy of Sciences of the United States of America 108, 20760-20765.

Estrada, K.D., Retting, K.N., Chin, A.M., and Lyons, K.M. (2011). Smad6 is essential to limit BMP signaling during cartilage development. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 26, 2498-2510.

Fahey, L.M., Wilson, E.B., Elsaesser, H., Fistonich, C.D., McGavern, D.B., and Brooks, D.G. (2011). Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells. The Journal of experimental medicine 208, 987-999.

Guo, D., Reinitz, F., Youssef, M., Hong, C., Nathanson, D., Akhavan, D., Kuga, D., Amzajerdi, A.N., Soto, H., Zhu, S., et al. (2011a). An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway. Cancer discovery 1, 442-456.

Guo, H., Tse, L.V., Nieh, A.W., Czornyj, E., Williams, S., Oukil, S., Liu, V.B., and Miller, J.F. (2011b). Target site recognition by a diversity-generating retroelement. PLoS genetics 7, e1002414.

Hill, S., Hirano, K., Shmanai, V.V., Marbois, B.N., Vidovic, D., Bekish, A.V., Kay, B., Tse, V., Fine, J., Clarke, C.F., et al. (2011). Isotope-reinforced polyunsaturated fatty acids protect yeast cells from oxidative stress. Free radical biology & medicine 50, 130-138.

Lee, S., Salwinski, L., Zhang, C., Chu, D., Sampankanpanich, C., Reyes, N.A., Vangeloff, A., Xing, F., Li, X., Wu, T.T., et al. (2011). An integrated approach to elucidate the intra-viral and viral-cellular protein interaction networks of a gamma-herpesvirus. PLoS pathogens 7, e1002297.

Liu, A., Fong, A., Becket, E., Yuan, J., Tamae, C., Medrano, L., Maiz, M., Wahba, C., Lee, C., Lee, K., et al. (2011). Selective advantage of resistant strains at trace levels of antibiotics: a simple and ultrasensitive color test for detection of antibiotics and genotoxic agents. Antimicrobial agents and chemotherapy 55, 1204-1210.

Roberts, A.C., Reichl, J., Song, M.Y., Dearinger, A.D., Moridzadeh, N., Lu, E.D., Pearce, K., Esdin, J., and Glanzman, D.L. (2011). Habituation of the C-start response in larval zebrafish exhibits several distinct phases and sensitivity to NMDA receptor blockade. PloS one 6, e29132.

Takashima, S., Adams, K.L., Ortiz, P.A., Ying, C.T., Moridzadeh, R., Younossi-Hartenstein, A., and Hartenstein, V. (2011). Development of the Drosophila entero-endocrine lineage and its specification by the Notch signaling pathway. Developmental biology 353, 161-172.

Tsang, E.J., Arakawa, C.K., Zuk, P.A., and Wu, B.M. (2011). Osteoblast interactions within a biomimetic apatite microenvironment. Annals of biomedical engineering 39, 1186-1200.

Vincent, J.J., Li, Z., Lee, S.A., Liu, X., Etter, M.O., Diaz-Perez, S.V., Taylor, S.K., Gkountela, S., Lindgren, A.G., and Clark, A.T. (2011). Single cell analysis facilitates staging of Blimp1-dependent primordial germ cells derived from mouse embryonic stem cells. PloS one 6, e28960.

Ziegler, M.D., Hsu, D., Takeoka, A., Zhong, H., Ramon-Cueto, A., Phelps, P.E., Roy, R.R., and Edgerton, V.R. (2011). Further evidence of olfactory ensheathing glia facilitating axonal regeneration after a complete spinal cord transection. Experimental neurology 229, 109-119.

2012

Arboleda, V.A., Lee, H., Parnaik, R., Fleming, A., Banerjee, A., Ferraz-de-Souza, B., Delot, E.C., Rodriguez-Fernandez, I.A., Braslavsky, D., Bergada, I., et al. (2012). Mutations in the PCNA-binding domain of CDKN1C cause IMAGe syndrome. Nature genetics 44, 788-792.

Bhatt, D.M., Pandya-Jones, A., Tong, A.J., Barozzi, I., Lissner, M.M., Natoli, G., Black, D.L., and Smale, S.T. (2012). Transcript dynamics of proinflammatory genes revealed by sequence analysis of subcellular RNA fractions. Cell 150, 279-290.

Biering, S.B., Huang, A., Vu, A.T., Robinson, L.R., Bradel-Tretheway, B., Choi, E., Lee, B., and Aguilar, H.C. (2012). N-Glycans on the Nipah virus attachment glycoprotein modulate fusion and viral entry as they protect against antibody neutralization. Journal of virology 86, 11991-12002.

Birukova, A.A., Lee, S., Starosta, V., Wu, T., Ho, T., Kim, J., Berliner, J.A., and Birukov, K.G. (2012). A role for VEGFR2 activation in endothelial responses caused by barrier disruptive OxPAPC concentrations. PloS one 7, e30957.

Ch'ng, T.H., Uzgil, B., Lin, P., Avliyakulov, N.K., O'Dell, T.J., and Martin, K.C. (2012). Activity-dependent transport of the transcriptional coactivator CRTC1 from synapse to nucleus. Cell 150, 207-221.

Choe, U.J., Sun, V.Z., Tan, J.K., and Kamei, D.T. (2012). Self-assembled polypeptide and polypeptide hybrid vesicles: from synthesis to application. Topics in current chemistry 310, 117-134.

Cruz-Martin, A., Crespo, M., and Portera-Cailliau, C. (2012). Glutamate induces the elongation of early dendritic protrusions via mGluRs in wild type mice, but not in fragile X mice. PloS one 7, e32446.

Donahue, T.R., Tran, L.M., Hill, R., Li, Y., Kovochich, A., Calvopina, J.H., Patel, S.G., Wu, N., Hindoyan, A., Farrell, J.J., et al. (2012). Integrative survival-based molecular profiling of human pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 18, 1352-1363.

Gomez, F., Monsalve, G.C., Tse, V., Saiki, R., Weng, E., Lee, L., Srinivasan, C., Frand, A.R., and Clarke, C.F. (2012). Delayed accumulation of intestinal coliform bacteria enhances life span and stress resistance in Caenorhabditis elegans fed respiratory deficient E. coli. BMC microbiology 12, 300.

Gossett, D.R., Tse, H.T., Dudani, J.S., Goda, K., Woods, T.A., Graves, S.W., and Di Carlo, D. (2012). Inertial manipulation and transfer of microparticles across laminar fluid streams. Small (Weinheim an der Bergstrasse, Germany) 8, 2757-2764.

Hall-Glenn, F., De Young, R.A., Huang, B.L., van Handel, B., Hofmann, J.J., Chen, T.T., Choi, A., Ong, J.R., Benya, P.D., Mikkola, H., et al. (2012). CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. PloS one 7, e30562.

Hill, R., Li, Y., Tran, L.M., Dry, S., Calvopina, J.H., Garcia, A., Kim, C., Wang, Y., Donahue, T.R., Herschman, H.R., et al. (2012). Cell intrinsic role of COX-2 in pancreatic cancer development. Molecular cancer therapeutics 11, 2127-2137.

Lamkin, D.M., Sloan, E.K., Patel, A.J., Chiang, B.S., Pimentel, M.A., Ma, J.C., Arevalo, J.M., Morizono, K., and Cole, S.W. (2012). Chronic stress enhances progression of acute lymphoblastic leukemia via beta-adrenergic signaling. Brain, behavior, and immunity 26, 635-641.

Macey, P.M., Wu, P., Kumar, R., Ogren, J.A., Richardson, H.L., Woo, M.A., and Harper, R.M. (2012). Differential responses of the insular cortex gyri to autonomic challenges. Autonomic neuroscience : basic & clinical 168, 72-81.

Marshall, J.L., Chou, E., Oh, J., Kwok, A., Burkin, D.J., and Crosbie-Watson, R.H. (2012). Dystrophin and utrophin expression require sarcospan: loss of alpha7 integrin exacerbates a newly discovered muscle phenotype in sarcospan-null mice. Human molecular genetics 21, 4378-4393.

Meloty-Kapella, L., Shergill, B., Kuon, J., Botvinick, E., and Weinmaster, G. (2012). Notch ligand endocytosis generates mechanical pulling force dependent on dynamin, epsins, and actin. Developmental cell 22, 1299-1312.

Monclus, R., Cook, T., and Blumstein, D.T. (2012). Masculinized female yellow-bellied marmots initiate more social interactions. Biology letters 8, 208-210.

Mukherjee, T., Choi, I., and Banerjee, U. (2012). Genetic analysis of fibroblast growth factor signaling in the Drosophila eye. G3 (Bethesda, Md) 2, 23-28.

Nsair, A., Schenke-Layland, K., Van Handel, B., Evseenko, D., Kahn, M., Zhao, P., Mendelis, J., Heydarkhan, S., Awaji, O., Vottler, M., Geist, S., Chyu, J.et al. (2012). Characterization and therapeutic potential of induced pluripotent stem cell-derived cardiovascular progenitor cells. PloS one 7, e45603.

Olson, C.A., Nie, J., Diep, J., Al-Shyoukh, I., Takahashi, T.T., Al-Mawsawi, L.Q., Bolin, J.M., Elwell, A.L., Swanson, S., Stewart, R., et al. (2012). Single-round, multiplexed antibody mimetic design through mRNA display. Angewandte Chemie (International ed in English) 51, 12449-12453.

Patterson, M., Chan, D.N., Ha, I., Case, D., Cui, Y., Van Handel, B., Mikkola, H.K., and Lowry, W.E. (2012). Defining the nature of human pluripotent stem cell progeny. Cell research 22, 178-193.

Rhee, K.D., Yu, J., Zhao, C.Y., Fan, G., and Yang, X.J. (2012). Dnmt1-dependent DNA methylation is essential for photoreceptor terminal differentiation and retinal neuron survival. Cell death & disease 3, e427.

2013

Akhavan, D., Pourzia, A.L., Nourian, A.A., Williams, K.J., Nathanson, D., Babic, I., Villa, G.R., Tanaka, K., Nael, A., Yang, H., et al. (2013). De-repression of PDGFRbeta transcription promotes acquired resistance to EGFR tyrosine kinase inhibitors in glioblastoma patients. Cancer discovery 3, 534-547.

Barkhordarian, A., Pellionisz, P., Dousti, M., Lam, V., Gleason, L., Dousti, M., Moura, J., and Chiappelli, F. (2013). Assessment of risk of bias in translational science. Journal of translational medicine 11, 184.

Chu, D., Ren, S., Hu, S., Wang, W.G., Subramanian, A., Contreras, D., Kanagavel, V., Chung, E., Ko, J., Amirtham Jacob Appadorai, R.S., et al. (2013). Systematic analysis of enhancer and critical cis-acting RNA elements in the protein-encoding region of the hepatitis C virus genome. Journal of virology 87, 5678-5696.

de Resende, M.F., Vieira, S., Chinen, L.T., Chiappelli, F., da Fonseca, F.P., Guimaraes, G.C., Soares, F.A., Neves, I., Pagotty, S., Pellionisz, P.A., et al. (2013). Prognostication of prostate cancer based on TOP2A protein and gene assessment: TOP2A in prostate cancer. Journal of translational medicine 11, 36.

Dudani, J.S., Gossett, D.R., Tse, H.T., and Di Carlo, D. (2013). Pinched-flow hydrodynamic stretching of single-cells. Lab on a chip 13, 3728-3734.

Garcia, A.J., Tom, C., Guemes, M., Polanco, G., Mayorga, M.E., Wend, K., Miranda-Carboni, G.A., and Krum, S.A. (2013). ERalpha signaling regulates MMP3 expression to induce FasL cleavage and osteoclast apoptosis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 28, 283-290.

Goddard, L.M., Ton, A.N., Org, T., Mikkola, H.K., and Iruela-Arispe, M.L. (2013). Selective suppression of endothelial cytokine production by progesterone receptor. Vascular pharmacology 59, 36-43.

Hall-Glenn, F., Aivazi, A., Akopyan, L., Ong, J.R., Baxter, R.R., Benya, P.D., Goldschmeding, R., van Nieuwenhoven, F.A., Hunziker, E.B., and Lyons, K.M. (2013). CCN2/CTGF is required for matrix organization and to protect growth plate chondrocytes from cellular stress. Journal of cell communication and signaling 7, 219-230.

Jiang, Z.K., Johnson, M., Moughon, D.L., Kuo, J., Sato, M., and Wu, L. (2013). Rapamycin enhances adenovirus-mediated cancer imaging and therapy in pre-immunized murine hosts. PloS one 8, e73650.

Kim, S.G., Jung, J.B., Dixit, D., Rovner, R., Jr., Zack, J.A., Baldwin, G.C., and Vatakis, D.N. (2013). Cocaine exposure enhances permissiveness of quiescent T cells to HIV infection. Journal of leukocyte biology 94, 835-843.

Milde, F., Lauw, S., Koumoutsakos, P., and Iruela-Arispe, M.L. (2013). The mouse retina in 3D: quantification of vascular growth and remodeling. Integrative biology : quantitative biosciences from nano to macro 5, 1426-1438.

Nakatsu, M.N., Vartanyan, L., Vu, D.M., Ng, M.Y., Li, X., and Deng, S.X. (2013). Preferential biological processes in the human limbus by differential gene profiling. PloS one 8, e61833.

Nixon, C.C., Vatakis, D.N., Reichelderfer, S.N., Dixit, D., Kim, S.G., Uittenbogaart, C.H., and Zack, J.A. (2013). HIV-1 infection of hematopoietic progenitor cells in vivo in humanized mice. Blood 122, 2195-2204.

Palanca, A.M., Lee, S.L., Yee, L.E., Joe-Wong, C., Trinh le, A., Hiroyasu, E., Husain, M., Fraser, S.E., Pellegrini, M., and Sagasti, A. (2013). New transgenic reporters identify somatosensory neuron subtypes in larval zebrafish. Developmental neurobiology 73, 152-167.

Schwartz, A.R., Ortiz, I., Maymon, M., Herbold, C.W., Fujishige, N.A., Vijanderan, J.A., Villella, W., Hanamoto, K., Diener, A., Sanders, E.R., et al. (2013). Bacillus simplex—A Little Known PGPB with Anti-Fungal Activity—Alters Pea Legume Root Architecture and Nodule Morphology When Coinoculated with Rhizobium leguminosarum bv. viciae. Agronomy 3, 595-620.

Shim, J., Mukherjee, T., Mondal, B.C., Liu, T., Young, G.C., Wijewarnasuriya, D.P., and Banerjee, U. (2013). Olfactory control of blood progenitor maintenance. Cell 155, 1141-1153.

Sun, Y., Hu, Z., Goeb, Y., and Dreier, L. (2013). The F-box protein MEC-15 (FBXW9) promotes synaptic transmission in GABAergic motor neurons in C. elegans. PloS one 8, e59132.

Tran, C.M., Fujita, N., Huang, B.L., Ong, J.R., Lyons, K.M., Shapiro, I.M., and Risbud, M.V. (2013a). Hypoxia-inducible factor (HIF)-1alpha and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1alpha level and transcriptional activity. The Journal of biological chemistry 288, 12654-12666.

Tran, T., Andersen, R., Sherman, S.P., and Pyle, A.D. (2013b). Insights into skeletal muscle development and applications in regenerative medicine. International review of cell and molecular biology 300, 51-83.

Turlo, K.A., Scapa, J., Bagher, P., Jones, A.W., Feil, R., Korthuis, R.J., Segal, S.S., and Iruela-Arispe, M.L. (2013). beta1-integrin is essential for vasoregulation and smooth muscle survival in vivo. Arteriosclerosis, thrombosis, and vascular biology 33, 2325-2335.

Varshney, G.K., Lu, J., Gildea, D.E., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D., Pho, N.H., Casero, D., Hirase, T., et al. (2013). A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research 23, 727-735.

Vincent, J.J., Huang, Y., Chen, P.Y., Feng, S., Calvopina, J.H., Nee, K., Lee, S.A., Le, T., Yoon, A.J., Faull, K., et al. (2013). Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells. Cell stem cell 12, 470-478.

Williams, K.J., Argus, J.P., Zhu, Y., Wilks, M.Q., Marbois, B.N., York, A.G., Kidani, Y., Pourzia, A.L., Akhavan, D., Lisiero, D.N., et al. (2013). An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity. Cancer research 73, 2850-2862.

Zhang, X., Guo, H., Jin, L., Czornyj, E., Hodes, A., Hui, W.H., Nieh, A.W., Miller, J.F., and Zhou, Z.H. (2013). A new topology of the HK97-like fold revealed in Bordetella bacteriophage by cryoEM at 3.5 A resolution. eLife 2, e01299.

2014

Arakawa, C., Ng, R., Tan, S., Kim, S., Wu, B., and Lee, M. (2014). Photopolymerizable chitosan-collagen hydrogels for bone tissue engineering. Journal of tissue engineering and regenerative medicine.

Castelletto, M.L., Gang, S.S., Okubo, R.P., Tselikova, A.A., Nolan, T.J., Platzer, E.G., Lok, J.B., and Hallem, E.A. (2014). Diverse host-seeking behaviors of skin-penetrating nematodes. PLoS pathogens 10, e1004305.

Chen, Y., Akin, O., Nern, A., Tsui, C.Y., Pecot, M.Y., and Zipursky, S.L. (2014). Cell-type-specific labeling of synapses in vivo through synaptic tagging with recombination. Neuron 81, 280-293.

Clark, P.M., Flores, G., Evdokimov, N.M., McCracken, M.N., Chai, T., Nair-Gill, E., O'Mahony, F., Beaven, S.W., Faull, K.F., Phelps, M.E., et al. (2014). Positron emission tomography probe demonstrates a striking concentration of ribose salvage in the liver. Proceedings of the National Academy of Sciences of the United States of America 111, E2866-2874.

Demagny, H., Araki, T., and De Robertis, E.M. (2014). The tumor suppressor Smad4/DPC4 is regulated by phosphorylations that integrate FGF, Wnt, and TGF-beta signaling. Cell reports 9, 688-700.

Dudani, J.S., Go, D.E., Gossett, D.R., Tan, A.P., and Di Carlo, D. (2014). Mediating millisecond reaction time around particles and cells. Analytical chemistry 86, 1502-1510.

Eshraghi, A., Dixon, S.D., Tamilselvam, B., Kim, E.J., Gargi, A., Kulik, J.C., Damoiseaux, R., Blanke, S.R., and Bradley, K.A. (2014). Cytolethal distending toxins require components of the ER-associated degradation pathway for host cell entry. PLoS pathogens 10, e1004295.

Gkountela, S., Li, Z., Chin, C.J., Lee, S.A., and Clark, A.T. (2014). PRMT5 is required for human embryonic stem cell proliferation but not pluripotency. Stem cell reviews 10, 230-239.

Gluck, J.M., Delman, C., Chyu, J., MacLellan, W.R., Shemin, R.J., and Heydarkhan-Hagvall, S. (2014). Microenvironment influences vascular differentiation of murine cardiovascular progenitor cells. Journal of biomedical materials research Part B, Applied biomaterials 102, 1730-1739.

Gong, D., Wu, N.C., Xie, Y., Feng, J., Tong, L., Brulois, K.F., Luan, H., Du, Y., Jung, J.U., Wang, C.Y., et al. (2014). Kaposi's sarcoma-associated herpesvirus ORF18 and ORF30 are essential for late gene expression during lytic replication. Journal of virology 88, 11369-11382.

Kim, W.S., Zhu, Y., Deng, Q., Chin, C.J., He, C.B., Grieco, A.J., Dravid, G.G., Parekh, C., Hollis, R.P., Lane, T.F., et al. (2014). Erythropoiesis from human embryonic stem cells through erythropoietin-independent AKT signaling. Stem cells (Dayton, Ohio) 32, 1503-1514.

Lawal, H.O., Terrell, A., Lam, H.A., Djapri, C., Jang, J., Hadi, R., Roberts, L., Shahi, V., Chou, M.T., Biedermann, T., et al. (2014). Drosophila modifier screens to identify novel neuropsychiatric drugs including aminergic agents for the possible treatment of Parkinson's disease and depression. Molecular psychiatry 19, 235-242.

Li, Z., Yu, J., Hosohama, L., Nee, K., Gkountela, S., Chaudhari, S., Cass, A.A., Xiao, X., and Clark, A.T. (2014). The Sm protein methyltransferase PRMT5 is not required for primordial germ cell specification in mice. The EMBO journal.

McVerry, B.T., Wong, M.C., Marsh, K.L., Temple, J.A., Marambio-Jones, C., Hoek, E.M., and Kaner, R.B. (2014). Scalable antifouling reverse osmosis membranes utilizing perfluorophenyl azide photochemistry. Macromolecular rapid communications 35, 1528-1533.

Montecino-Rodriguez, E., Li, K., Fice, M., and Dorshkind, K. (2014). Murine B-1 B cell progenitors initiate B-acute lymphoblastic leukemia with features of high-risk disease. Journal of immunology (Baltimore, Md : 1950) 192, 5171-5178.

Nakashima, Y., Yanez, D.A., Touma, M., Nakano, H., Jaroszewicz, A., Jordan, M.C., Pellegrini, M., Roos, K.P., and Nakano, A. (2014). Nkx2-5 suppresses the proliferation of atrial myocytes and conduction system. Circulation research 114, 1103-1113.

Nathanson, D.A., Armijo, A.L., Tom, M., Li, Z., Dimitrova, E., Austin, W.R., Nomme, J., Campbell, D.O., Ta, L., Le, T.M., et al. (2014). Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication. The Journal of experimental medicine 211, 473-486.

O'Donnell, K.C., Lulla, A., Stahl, M.C., Wheat, N.D., Bronstein, J.M., and Sagasti, A. (2014). Axon degeneration and PGC-1alpha-mediated protection in a zebrafish model of alpha-synuclein toxicity. Disease models & mechanisms 7, 571-582.

Pasque, V., Tchieu, J., Karnik, R., Uyeda, M., Sadhu Dimashkie, A., Case, D., Papp, B., Bonora, G., Patel, S., Ho, R., et al. (2014). X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency. Cell 159, 1681-1697.

Pastor, W.A., Stroud, H., Nee, K., Liu, W., Pezic, D., Manakov, S., Lee, S.A., Moissiard, G., Zamudio, N., Bourc'his, D., et al. (2014). MORC1 represses transposable elements in the mouse male germline. Nature communications 5, 5795.

Patterson, M., Gaeta, X., Loo, K., Edwards, M., Smale, S., Cinkornpumin, J., Xie, Y., Listgarten, J., Azghadi, S., Douglass, S.M., et al. (2014). let-7 miRNAs can act through notch to regulate human gliogenesis. Stem cell reports 3, 758-773.

Pecot, M.Y., Chen, Y., Akin, O., Chen, Z., Tsui, C.Y., and Zipursky, S.L. (2014). Sequential axon-derived signals couple target survival and layer specificity in the Drosophila visual system. Neuron 82, 320-333.

Quick-Cleveland, J., Jacob, J.P., Weitz, S.H., Shoffner, G., Senturia, R., and Guo, F. (2014). The DGCR8 RNA-binding heme domain recognizes primary microRNAs by clamping the hairpin. Cell reports 7, 1994-2005.

Rigueur, D., Brugger, S., Anbarchian, T., Kim, J.K., Lee, Y.J., and Lyons, K. (2014). The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Stroud, H., Do, T., Du, J., Zhong, X., Feng, S., Johnson, L., Patel, D.J., and Jacobsen, S.E. (2014). Non-CG methylation patterns shape the epigenetic landscape in Arabidopsis. Nature structural & molecular biology 21, 64-72.

Tan, A.P., Dudani, J.S., Arshi, A., Lee, R.J., Tse, H.T., Gossett, D.R., and Di Carlo, D. (2014). Continuous-flow cytomorphological staining and analysis. Lab on a chip 14, 522-531.

Weaver, W.M., Tseng, P., Kunze, A., Masaeli, M., Chung, A.J., Dudani, J.S., Kittur, H., Kulkarni, R.P., and Di Carlo, D. (2014). Advances in high-throughput single-cell microtechnologies. Current opinion in biotechnology 25, 114-123.

Wong, D.M., Shen, Z., Owyang, K.E., and Martinez-Agosto, J.A. (2014). Insulin- and warts-dependent regulation of tracheal plasticity modulates systemic larval growth during hypoxia in Drosophila melanogaster. PloS one 9, e115297.

Wu, N.C., De La Cruz, J., Al-Mawsawi, L.Q., Olson, C.A., Qi, H., Luan, H.H., Nguyen, N., Du, Y., Le, S., Wu, T.T., et al. (2014a). HIV-1 quasispecies delineation by tag linkage deep sequencing. PloS one 9, e97505.

Wu, N.C., Young, A.P., Al-Mawsawi, L.Q., Olson, C.A., Feng, J., Qi, H., Chen, S.H., Lu, I.H., Lin, C.Y., Chin, R.G., Luan, H.H., et al. (2014b). High-throughput profiling of influenza A virus hemagglutinin gene at single-nucleotide resolution. Scientific reports 4, 4942.

Wu, N.C., Young, A.P., Al-Mawsawi, L.Q., Olson, C.A., Feng, J., Qi, H., Luan, H.H., Li, X., Wu, T.T., and Sun, R. (2014c). High-throughput identification of loss-of-function mutations for anti-interferon activity in the influenza A virus NS segment. Journal of virology 88, 10157-10164.

Xie, Y., Zhang, J., Lin, Y., Gaeta, X., Meng, X., Wisidagama, D.R., Cinkornpumin, J., Koehler, C.M., Malone, C.S., Teitell, M.A., et al. (2014). Defining the role of oxygen tension in human neural progenitor fate. Stem cell reports 3, 743-757.

Zhen, A., Krutzik, S.R., Levin, B.R., Kasparian, S., Zack, J.A., and Kitchen, S.G. (2014). CD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infection. Journal of virology 88, 9934-9946.

2015

Arcizet, F., Mirpour, K., Foster, D.J., Charpentier, C.J., and Bisley, J.W. (2015). LIP activity in the interstimulus interval of a change detection task biases the behavioral response. Journal of neurophysiology 114, 2637-2648.

Berent-Maoz, B., Montecino-Rodriguez, E., Fice, M., Casero, D., Seet, C.S., Crooks, G.M., Lowry, W., and Dorshkind, K. (2015). The expansion of thymopoiesis in neonatal mice is dependent on expression of high mobility group a 2 protein (hmga2). PloS one 10, e0125414.

Briot, A., Civelek, M., Seki, A., Hoi, K., Mack, J.J., Lee, S.D., Kim, J., Hong, C., Yu, J., Fishbein, G.A., et al. (2015). Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis. The Journal of experimental medicine 212, 2147-2163.

Ch'ng, T.H., DeSalvo, M., Lin, P., Vashisht, A., Wohlschlegel, J.A., and Martin, K.C. (2015). Cell biological mechanisms of activity-dependent synapse to nucleus translocation of CRTC1 in neurons. Frontiers in molecular neuroscience 8, 48.

Chen, A.L., Kim, E.W., Toh, J.Y., Vashisht, A.A., Rashoff, A.Q., Van, C., Huang, A.S., Moon, A.S., Bell, H.N., Bentolila, L.A., et al. (2015). Novel components of the Toxoplasma inner membrane complex revealed by BioID. mBio 6, e02357-02314.

Domigan, C.K., Warren, C.M., Antanesian, V., Happel, K., Ziyad, S., Lee, S., Krall, A., Duan, L., Torres-Collado, A.X., Castellani, L.W., et al. (2015). Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy. Journal of cell science.

Dudani, J.S., Gossett, D.R., Tse, H.T., Lamm, R.J., Kulkarni, R.P., and Carlo, D.D. (2015). Rapid inertial solution exchange for enrichment and flow cytometric detection of microvesicles. Biomicrofluidics 9, 014112.

Ear, J., Huang, H., Wilson, T., Tehrani, Z., Lindgren, A., Sung, V., Laadem, A., Daniel, T.O., Chopra, R., and Lin, S. (2015). RAP-011 improves erythropoiesis in zebrafish model of Diamond-Blackfan anemia through antagonizing lefty1. Blood 126, 880-890.

Evdokimov, N.M., Clark, P.M., Flores, G., Chai, T., Faull, K.F., Phelps, M.E., Witte, O.N., and Jung, M.E. (2015). Development of 2-Deoxy-2-[(18)F]fluororibose for Positron Emission Tomography Imaging Liver Function in Vivo. Journal of medicinal chemistry 58, 5538-5547.

Feng, J., Gong, D., Fu, X., Wu, T.T., Wang, J., Chang, J., Zhou, J., Lu, G., Wang, Y., and Sun, R. (2015). M1 of Murine Gamma-Herpesvirus 68 Induces Endoplasmic Reticulum Chaperone Production. Scientific reports 5, 17228.

Gholkar, A.A., Senese, S., Lo, Y.C., Capri, J., Deardorff, W.J., Dharmarajan, H., Contreras, E., Hodara, E., Whitelegge, J.P., Jackson, P.K., et al. (2015). Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis. Cell cycle (Georgetown, Tex) 14, 1116-1125.

Gkountela, S., Zhang, K.X., Shafiq, T.A., Liao, W.W., Hargan-Calvopina, J., Chen, P.Y., and Clark, A.T. (2015). DNA Demethylation Dynamics in the Human Prenatal Germline. Cell 161, 1425-1436.

Hargan Calvopina, J., Cook, H., Vincent, J., Nee, K., and Clark, A. (2015). The Aorta Gonad Mesonephros organ culture recapitulates 5hmC reorganization and replication-dependent and independent loss of DNA methylation in the germline. Stem cells and development.

Hoban, M.D., Cost, G.J., Mendel, M.C., Romero, Z., Kaufman, M.L., Joglekar, A.V., Ho, M., Lumaquin, D., Gray, D., Lill, G.R., et al. (2015a). Correction of the sickle-cell disease mutation in human hematopoietic stem/progenitor cells. Blood.

Hoban, M.D., Cost, G.J., Mendel, M.C., Romero, Z., Kaufman, M.L., Joglekar, A.V., Ho, M., Lumaquin, D., Gray, D., Lill, G.R., et al. (2015b). Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells. Blood 125, 2597-2604.

Kim, S.G., Lowe, E.L., Dixit, D., Youn, C.S., Kim, I.J., Jung, J.B., Rovner, R., Zack, J.A., and Vatakis, D.N. (2015). Cocaine-mediated impact on HIV infection in humanized BLT mice. Scientific reports 5, 10010.

Kong, J.H., Yang, L., Dessaud, E., Chuang, K., Moore, D.M., Rohatgi, R., Briscoe, J., and Novitch, B.G. (2015). Notch Activity Modulates the Responsiveness of Neural Progenitors to Sonic Hedgehog Signaling. Developmental cell.

Kwon, M.H., Zhang, J.Q., Schaenman, J.M., Cadeiras, M., Gjertson, D.W., Krystal, C.A., Laks, H., Ardehali, A., Deng, M.C., Shemin, R.J., et al. (2015). Characterization of ventricular assist device-mediated sensitization in the bridge-to-heart-transplantation patient. The Journal of thoracic and cardiovascular surgery 149, 1161-1166.

Li, Q., Loh, D.H., Kudo, T., Truong, D., Derakhshesh, M., Kaswan, Z.M., Ghiani, C.A., Tsoa, R., Cheng, Y., Sun, Y.E., et al. (2015). Circadian rhythm disruption in a mouse model of Rett syndrome circadian disruption in RTT. Neurobiology of disease 77, 155-164.

Lissner, M.M., Thomas, B.J., Wee, K., Tong, A.J., Kollmann, T.R., and Smale, S.T. (2015). Age-Related Gene Expression Differences in Monocytes from Human Neonates, Young Adults, and Older Adults. PloS one 10, e0132061.

Lluri, G., Huang, V., Touma, M., Liu, X., Harmon, A.W., and Nakano, A. (2015). Hematopoietic progenitors are required for proper development of coronary vasculature. Journal of molecular and cellular cardiology 86, 199-207.

Madsen, S.K., Zai, A., Pirnia, T., Arienzo, D., Zhan, L., Moody, T.D., Thompson, P.M., and Feusner, J.D. (2015). Cortical thickness and brain volumetric analysis in body dysmorphic disorder. Psychiatry research 232, 115-122.

McCracken, M.N., Vatakis, D.N., Dixit, D., McLaughlin, J., Zack, J.A., and Witte, O.N. (2015). Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging. The Journal of clinical investigation 125, 1815-1826.

Miquelajauregui, A., Kribakaran, S., Mostany, R., Badaloni, A., Consalez, G.G., and Portera-Cailliau, C. (2015). Layer 4 pyramidal neurons exhibit robust dendritic spine plasticity in vivo after input deprivation. The Journal of neuroscience : the official journal of the Society for Neuroscience 35, 7287-7294.

Morselli, M., Pastor, W.A., Montanini, B., Nee, K., Ferrari, R., Fu, K., Bonora, G., Rubbi, L., Clark, A.T., Ottonello, S., et al. (2015). In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse. eLife 4, e06205.

Nixon, C.C., Schwartz, B.H., Dixit, D., Zack, J.A., and Vatakis, D.N. (2015). Cocaine exposure impairs multineage hematopoiesis of human hematopoietic progenitor cells mediated by the sigma-1 receptor. Scientific reports 5, 8670.

Oliveros-Etter, M., Li, Z., Nee, K., Hosohama, L., Hargan-Calvopina, J., Lee, S.A., Joti, P., Yu, J., and Clark, A.T. (2015). PGC Reversion to Pluripotency Involves Erasure of DNA Methylation from Imprinting Control Centers followed by Locus-Specific Re-methylation. Stem cell reports 5, 337-349.

Oztug Durer, Z.A., McGillivary, R.M., Kang, H., Elam, W.A., Vizcarra, C.L., Hanein, D., De La Cruz, E.M., Reisler, E., and Quinlan, M.E. (2015). Metavinculin Tunes the Flexibility and the Architecture of Vinculin-Induced Bundles of Actin Filaments. Journal of molecular biology 427, 2782-2798.

Parvatiyar, M.S., Marshall, J.L., Nguyen, R.T., Jordan, M.C., Richardson, V.A., Roos, K.P., and Crosbie-Watson, R.H. (2015). Sarcospan Regulates Cardiac Isoproterenol Response and Prevents Duchenne Muscular Dystrophy-Associated Cardiomyopathy. Journal of the American Heart Association 4.

Pena, J.M., Carrillo, M.A., and Hallem, E.A. (2015). Variation in the susceptibility of Drosophila to different entomopathogenic nematodes. Infection and immunity 83, 1130-1138.

Pentecost, M., Vashisht, A.A., Lester, T., Voros, T., Beaty, S.M., Park, A., Wang, Y.E., Yun, T.E., Freiberg, A.N., Wohlschlegel, J.A., et al. (2015). Evidence for ubiquitin-regulated nuclear and subnuclear trafficking among Paramyxovirinae matrix proteins. PLoS pathogens 11, e1004739.

Prashad, S.L., Calvanese, V., Yao, C.Y., Kaiser, J., Wang, Y., Sasidharan, R., Crooks, G., Magnusson, M., and Mikkola, H.K. (2015). GPI-80 Defines Self-Renewal Ability in Hematopoietic Stem Cells during Human Development. Cell stem cell 16, 80-87.

Romay, M.C., Che, N., Becker, S.N., Pouldar, D., Hagopian, R., Xiao, X., Lusis, A.J., Berliner, J.A., and Civelek, M. (2015). Regulation of NF-kappaB signaling by oxidized glycerophospholipid and IL-1beta induced miRs-21-3p and -27a-5p in human aortic endothelial cells. Journal of lipid research 56, 38-50.

Romero, Z., Campo-Fernandez, B., Wherley, J., Kaufman, M.L., Urbinati, F., Cooper, A.R., Hoban, M.D., Baldwin, K.M., Lumaquin, D., Wang, X., et al. (2015). The human ankyrin 1 promoter insulator sustains gene expression in a beta-globin lentiviral vector in hematopoietic stem cells. Molecular therapy Methods & clinical development 2, 15012.

Ruscetti, M., Quach, B., Dadashian, E.L., Mulholland, D.J., and Wu, H. (2015). Tracking and Functional Characterization of Epithelial-Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis. Cancer research 75, 2749-2759.

Sanchez, D.J., Miranda, D., Jr., Marsden, M.D., Dizon, T.M., Bontemps, J.R., Davila, S.J., Del Mundo, L.E., Ha, T., Senaati, A., Zack, J.A., et al. (2015). Disruption of Type I Interferon Induction by HIV Infection of T Cells. PloS one 10, e0137951.

Sen, S., Kawahara, B., Gupta, D., Tsai, R., Khachatryan, M., Roy-Chowdhuri, S., Bose, S., Yoon, A., Faull, K., Farias-Eisner, R., et al. (2015). Role of cystathionine beta-synthase in human breast Cancer. Free radical biology & medicine 86, 228-238.

Tariq, M., Lum, M.R., Chong, A.W., Amirapu, A.B., Hameed, S., and Hirsch, A.M. (2015). A reliable method for the selection and confirmation of transconjugants of plant growth-promoting bacteria especially plant-associated Burkholderia spp. Journal of microbiological methods 117, 49-53.

Thames, A.D., Sayegh, P., Terashima, K., Foley, J.M., Cho, A., Arentoft, A., Hinkin, C.H., and Bookheimer, S.Y. (2015). Increased subcortical neural activity among HIV+ individuals during a lexical retrieval task. Neurobiology of disease.

Upton, M., and Lotfipour, S. (2015). alpha2-Null mutant mice have altered levels of neuronal activity in restricted midbrain and limbic brain regions during nicotine withdrawal as demonstrated by cfos expression. Biochemical pharmacology 97, 558-565.

Xie, L.X., Williams, K.J., He, C.H., Weng, E., Khong, S., Rose, T.E., Kwon, O., Bensinger, S.J., Marbois, B.N., and Clarke, C.F. (2015). Resveratrol and para-coumarate serve as ring precursors for coenzyme Q biosynthesis. Journal of lipid research 56, 909-919.

Yamin, G., Huynh, T.P., and Teplow, D.B. (2015). Design and Characterization of Chemically Stabilized Abeta42 Oligomers. Biochemistry 54, 5315-5321.

York, A.G., Williams, K.J., Argus, J.P., Zhou, Q.D., Brar, G., Vergnes, L., Gray, E.E., Zhen, A., Wu, N.C., Yamada, D.H., Cunningham, C.R., Tarling, E.J., Wilks, M.Q., Casero, D., Gray, D.H., Yu, A.K., et al. (2015). Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling. Cell 163, 1716-1729.

Zhen, A., Kamata, M., Rezek, V., Rick, J., Levin, B., Kasparian, S., Chen, I.S., Yang, O.O., Zack, J.A., and Kitchen, S.G. (2015). HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem Cells. Molecular therapy : the journal of the American Society of Gene Therapy 23, 1358-1367.

2016

Antonios, J.P., Soto, H., Everson, R.G., Orpilla, J., Moughon, D., Shin, N., Sedighim, S., Yong, W.H., Li, G., Cloughesy, T.F., et al. (2016). PD-1 blockade enhances the vaccination-induced immune response in glioma. JCI insight 1.

Bramble, M.S., Goldstein, E.H., Lipson, A., Ngun, T., Eskin, A., Gosschalk, J.E., Roach, L., Vashist, N., Barseghyan, H., Lee, E., et al. (2016a). A novel follicle-stimulating hormone receptor mutation causing primary ovarian failure: a fertility application of whole exome sequencing. Human reproduction (Oxford, England) 31, 905-914.

Bramble, M.S., Roach, L., Lipson, A., Vashist, N., Eskin, A., Ngun, T., Gosschalk, J.E., Klein, S., Barseghyan, H., Arboleda, V.A., et al. (2016b). Sex-Specific Effects of Testosterone on the Sexually Dimorphic Transcriptome and Epigenome of Embryonic Neural Stem/Progenitor Cells. Scientific reports 6, 36916.

Cai, D.J., Aharoni, D., Shuman, T., Shobe, J., Biane, J., Song, W., Wei, B., Veshkini, M., La-Vu, M., Lou, J., et al. (2016). A shared neural ensemble links distinct contextual memories encoded close in time. Nature 534, 115-118.

Chen, A.L., Moon, A.S., Bell, H.N., Huang, A.S., Vashisht, A.A., Toh, J.Y., Lin, A.H., Nadipuram, S.M., Kim, E.W., Choi, C.P., et al. (2016). Novel insights into the composition and function of the Toxoplasma IMC sutures. Cellular microbiology.

Chin, C.J., Cooper, A.R., Lill, G.R., Evseenko, D., Zhu, Y., He, C.B., Casero, D., Pellegrini, M., Kohn, D.B., and Crooks, G.M. (2016). Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors. Stem cells (Dayton, Ohio) 34, 1239-1250.

Damianov, A., Ying, Y., Lin, C.H., Lee, J.A., Tran, D., Vashisht, A.A., Bahrami-Samani, E., Xing, Y., Martin, K.C., Wohlschlegel, J.A., et al. (2016). Rbfox Proteins Regulate Splicing as Part of a Large Multiprotein Complex LASR. Cell 165, 606-619.

Ding, Y., Colozza, G., Zhang, K., Moriyama, Y., Ploper, D., Sosa, E.A., Benitez, M.D., and De Robertis, E.M. (2016). Genome-wide analysis of dorsal and ventral transcriptomes of the Xenopus laevis gastrula. Developmental biology.

Dou, D.R., Calvanese, V., Sierra, M.I., Nguyen, A.T., Minasian, A., Saarikoski, P., Sasidharan, R., Ramirez, C.M., Zack, J.A., Crooks, G.M., et al. (2016). Medial HOXA genes demarcate haematopoietic stem cell fate during human development. Nature cell biology 18, 595-606.

Du, Y., Wu, N.C., Jiang, L., Zhang, T., Gong, D., Shu, S., Wu, T.T., and Sun, R. (2016). Annotating Protein Functional Residues by Coupling High-Throughput Fitness Profile and Homologous-Structure Analysis. mBio 7.

Dumesic, D.A., Guedikian, A.A., Madrigal, V.K., Phan, J.D., Hill, D.L., Alvarez, J.P., and Chazenbalk, G.D. (2016). Cumulus Cell Mitochondrial Resistance to Stress In Vitro Predicts Oocyte Development During Assisted Reproduction. The Journal of clinical endocrinology and metabolism 101, 2235-2245.

Ear, J., Hsueh, J., Nguyen, M., Zhang, Q., Sung, V., Chopra, R., Sakamoto, K.M., and Lin, S. (2016). A Zebrafish Model of 5q-Syndrome Using CRISPR/Cas9 Targeting RPS14 Reveals a p53-Independent and p53-Dependent Mechanism of Erythroid Failure. Journal of genetics and genomics = Yi chuan xue bao 43, 307-318.

Gholkar, A.A., Senese, S., Lo, Y.C., Vides, E., Contreras, E., Hodara, E., Capri, J., Whitelegge, J.P., and Torres, J.Z. (2016). The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division. Cell reports 14, 180-188.

Gong, D., Kim, Y.H., Xiao, Y., Du, Y., Xie, Y., Lee, K.K., Feng, J., Farhat, N., Zhao, D., Shu, S., et al. (2016). A Herpesvirus Protein Selectively Inhibits Cellular mRNA Nuclear Export. Cell host & microbe 20, 642-653.

Gu, W., Gaeta, X., Sahakyan, A., Chan, A.B., Hong, C.S., Kim, R., Braas, D., Plath, K., Lowry, W.E., and Christofk, H.R. (2016). Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State. Cell stem cell 19, 476-490.

Hargan-Calvopina, J., Taylor, S., Cook, H., Hu, Z., Lee, S.A., Yen, M.R., Chiang, Y.S., Chen, P.Y., and Clark, A.T. (2016). Stage-Specific Demethylation in Primordial Germ Cells Safeguards against Precocious Differentiation. Developmental cell 39, 75-86.

Hoban, M.D., Lumaquin, D., Kuo, C.Y., Romero, Z., Long, J., Ho, M., Young, C.S., Mojadidi, M., Fitz-Gibbon, S., Cooper, A.R., et al. (2016). CRISPR/Cas9-Mediated Correction of the Sickle Mutation in Human CD34+ cells. Molecular therapy : the journal of the American Society of Gene Therapy 24, 1561-1569.

Hsu, M.S., Sedighim, S., Wang, T., Antonios, J.P., Everson, R.G., Tucker, A.M., Du, L., Emerson, R., Yusko, E., Sanders, C., et al. (2016). TCR Sequencing Can Identify and Track Glioma-Infiltrating T Cells after DC Vaccination. Cancer immunology research 4, 412-418.

Izquierdo, A., Pozos, H., Torre Ade, L., DeShields, S., Cevallos, J., Rodriguez, J., and Stolyarova, A. (2016). Sex differences, learning flexibility, and striatal dopamine D1 and D2 following adolescent drug exposure in rats. Behavioural brain research 308, 104-114.

Jiang, J., Leong, N.L., Khalique, U., Phan, T.M., Lyons, K.M., and Luck, J.V., Jr. (2016). Connective tissue growth factor (CTGF/CCN2) in haemophilic arthropathy and arthrofibrosis: a histological analysis. Haemophilia : the official journal of the World Federation of Hemophilia 22, e527-e536.

Khankan, R.R., Griffis, K.G., Haggerty-Skeans, J.R., Zhong, H., Roy, R.R., Edgerton, V.R., and Phelps, P.E. (2016). Olfactory Ensheathing Cell Transplantation after a Complete Spinal Cord Transection Mediates Neuroprotective and Immunomodulatory Mechanisms to Facilitate Regeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience 36, 6269-6286.

Laks, D.R., Ta, L., Crisman, T.J., Gao, F., Coppola, G., Radu, C.G., Nathanson, D.A., and Kornblum, H.I. (2016). Inhibition of Nucleotide Synthesis Targets Brain Tumor Stem Cells in a Subset of Glioblastoma. Molecular cancer therapeutics.

Lee, P.C., Truong, B., Vega-Crespo, A., Gilmore, W.B., Hermann, K., Angarita, S.A., Tang, J.K., Chang, K.M., Wininger, A.E., Lam, A.K., Schoenberg, B.E., et al. (2016). Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells. Molecular therapy Nucleic acids 5, e394.

Lillo, M.A., Nichols, C., Perry, C., Runke, S., Krutilina, R., Seagroves, T.N., Miranda-Carboni, G.A., and Krum, S.A. (2016). Methylparaben stimulates tumor initiating cells in ER+ breast cancer models. Journal of applied toxicology : JAT.

Matynia, A., Nguyen, E., Sun, X., Blixt, F.W., Parikh, S., Kessler, J., Perez de Sevilla Muller, L., Habib, S., Kim, P., Wang, Z.Z., et al. (2016). Peripheral Sensory Neurons Expressing Melanopsin Respond to Light. Frontiers in neural circuits 10, 60.

Nadipuram, S.M., Kim, E.W., Vashisht, A.A., Lin, A.H., Bell, H.N., Coppens, I., Wohlschlegel, J.A., and Bradley, P.J. (2016). In Vivo Biotinylation of the Toxoplasma Parasitophorous Vacuole Reveals Novel Dense Granule Proteins Important for Parasite Growth and Pathogenesis. mBio 7.

Nguyen, T.P., Sovari, A.A., Pezhouman, A., Iyer, S., Cao, H., Ko, C.Y., Bapat, A., Vahdani, N., Ghanim, M., Fishbein, M.C., et al. (2016). Increased susceptibility of spontaneously hypertensive rats to ventricular tachyarrhythmias in early hypertension. The Journal of physiology 594, 1689-1707.

Pastor, W.A., Chen, D., Liu, W., Kim, R., Sahakyan, A., Lukianchikov, A., Plath, K., Jacobsen, S.E., and Clark, A.T. (2016). Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory. Cell stem cell 18, 323-329.

Rodriguez, A., Gonzalez, L., Ko, A., Alvarez, M., Miao, Z., Bhagat, Y., Nikkola, E., Cruz-Bautista, I., Arellano-Campos, O., Munoz-Hernandez, L.L., et al. (2016). Molecular Characterization of the Lipid Genome-Wide Association Study Signal on Chromosome 18q11.2 Implicates HNF4A-Mediated Regulation of the TMEM241 Gene. Arteriosclerosis, thrombosis, and vascular biology 36, 1350-1355.

Ruscetti, M., Dadashian, E.L., Guo, W., Quach, B., Mulholland, D.J., Park, J.W., Tran, L.M., Kobayashi, N., Bianchi-Frias, D., Xing, Y., et al. (2016). HDAC inhibition impedes epithelial-mesenchymal plasticity and suppresses metastatic, castration-resistant prostate cancer. Oncogene 35, 3781-3795.

Simerman, A.A., Phan, J.D., Dumesic, D.A., and Chazenbalk, G.D. (2016). Muse Cells: Nontumorigenic Pluripotent Stem Cells Present in Adult Tissues-A Paradigm Shift in Tissue Regeneration and Evolution. Stem cells international 2016, 1463258.

Smith, D.J., Lin, L.J., Moon, H., Pham, A.T., Wang, X., Liu, S., Ji, S., Rezek, V., Shimizu, S., Ruiz, M., et al. (2016). Propagating Humanized BLT Mice for the Study of Human Immunology and Immunotherapy. Stem cells and development 25, 1863-1873.

Sosa, E., Kim, R., Rojas, E.J., Hosohama, L., Hennebold, J.D., Orwig, K.E., and Clark, A.T. (2016). An integration-free, virus-free rhesus macaque induced pluripotent stem cell line (riPSC89) from embryonic fibroblasts. Stem cell research 17, 444-447.

Sung, K., Ding, Y., Ma, J., Chen, H., Huang, V., Cheng, M., Yang, C.F., Kim, J.T., Eguchi, D., Di Carlo, D., et al. (2016). Simplified three-dimensional tissue clearing and incorporation of colorimetric phenotyping. Scientific reports 6, 30736.

TeSlaa, T., Chaikovsky, A.C., Lipchina, I., Escobar, S.L., Hochedlinger, K., Huang, J., Graeber, T.G., Braas, D., and Teitell, M.A. (2016). alpha-Ketoglutarate Accelerates the Initial Differentiation of Primed Human Pluripotent Stem Cells. Cell metabolism 24, 485-493.

Tong, A.J., Liu, X., Thomas, B.J., Lissner, M.M., Baker, M.R., Senagolage, M.D., Allred, A.L., Barish, G.D., and Smale, S.T. (2016). A Stringent Systems Approach Uncovers Gene-Specific Mechanisms Regulating Inflammation. Cell 165, 165-179.

Vega-Crespo, A., Truong, B., Hermann, K.J., Awe, J.P., Chang, K.M., Lee, P.C., Schoenberg, B.E., Wu, L., Byrne, J.A., and Lipshutz, G.S. (2016). Investigating the functionality of an OCT4-short response element in human induced pluripotent stem cells. Molecular therapy Methods & clinical development 3, 16050.

Wang, C.W., Purkayastha, A., Jones, K.T., Thaker, S.K., and Banerjee, U. (2016a). In vivo genetic dissection of tumor growth and the Warburg effect. eLife 5.

Wang, K., Peng, E.D., Huang, A.S., Xia, D., Vermont, S.J., Lentini, G., Lebrun, M., Wastling, J.M., and Bradley, P.J. (2016b). Identification of Novel O-Linked Glycosylated Toxoplasma Proteins by Vicia villosa Lectin Chromatography. PloS one 11, e0150561.

Wang, W., Song, B., Anbarchian, T., Shirazyan, A., Sadik, J.E., and Lyons, K.M. (2016c). Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate. PLoS genetics 12, e1006352.

Zhen, A., Rezek, V., Youn, C., Rick, J., Lam, B., Chang, N., Zack, J., Kamata, M., and Kitchen, S. (2016). Stem-cell Based Engineered Immunity Against HIV Infection in the Humanized Mouse Model. Journal of visualized experiments : JoVE.

2017

Alam, M., Garcia-Alias, G., Jin, B., Keyes, J., Zhong, H., Roy, R.R., Gerasimenko, Y., Lu, D.C., and Edgerton, V.R. (2017). Electrical neuromodulation of the cervical spinal cord facilitates forelimb skilled function recovery in spinal cord injured rats. Experimental neurology.

Antonios, J.P., Soto, H., Everson, R.G., Moughon, D., Orpilla, J.R., Shin, N.P., Sedighim, S., Treger, J., Odesa, S., Tucker, A., et al. (2017). Immunosuppressive tumor-infiltrating myeloid cells mediate adaptive immune resistance via a PD-1/PD-L1 mechanism in glioblastoma. Neuro-oncology.

Argus, J.P., Yu, A.K., Wang, E.S., Williams, K.J., and Bensinger, S.J. (2017). An optimized method for measuring fatty acids and cholesterol in stable isotope-labeled cells. Journal of lipid research 58, 460-468.

Cevallos, J.A., Okubo, R.P., Perlman, S.J., and Hallem, E.A. (2017). Olfactory Preferences of the Parasitic Nematode Howardula aoronymphium and its Insect Host Drosophila falleni. Journal of chemical ecology.

Dai, X., Li, Z., Lai, M., Shu, S., Du, Y., Zhou, Z.H., and Sun, R. (2017). In situ structures of the genome and genome-delivery apparatus in a single-stranded RNA virus. Nature 541, 112-116.

Gaeta, X., Le, L., Lin, Y., Xie, Y., and Lowry, W.E. (2017). Defining Transcriptional Regulatory Mechanisms for Primary let-7 miRNAs. PloS one 12, e0169237.

Hayden, E.Y., Conovaloff, J.L., Mason, A., Bitan, G., and Teplow, D.B. (2017). Preparation of pure populations of covalently stabilized amyloid beta-protein oligomers of specific sizes. Analytical biochemistry 518, 78-85.

Hickey, M.J., Zheng, Y., Valenzuela, N., Zhang, Q., Krystal, C., Lum, E., Tsai, E.W., Lipshutz, G.S., Gritsch, H.A., Danovitch, G., et al. (2017). New priorities: Analysis of the New Kidney Allocation System on UCLA patients transplanted from the deceased donor waitlist. Human immunology 78, 41-48.

Kermgard, E., Yang, Z., Michel, A.M., Simari, R., Wong, J., Ibba, M., and Lazazzera, B.A. (2017). Quality Control by Isoleucyl-tRNA Synthetase of Bacillus subtilis Is Required for Efficient Sporulation. Scientific reports 7, 41763.

Khialeeva, E., Chou, J.W., Allen, D.E., Chiu, A.M., Bensinger, S.J., and Carpenter, E.M. (2017). Reelin Deficiency Delays Mammary Tumor Growth and Metastatic Progression. Journal of mammary gland biology and neoplasia.

Pillai, I.C., Li, S., Romay, M., Lam, L., Lu, Y., Huang, J., Dillard, N., Zemanova, M., Rubbi, L., Wang, Y., et al. (2017). Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification. Cell stem cell 20, 218-232.e215.

Resende, L.P., Truong, M.E., Gomez, A., and Jones, D.L. (2017). Intestinal stem cell ablation reveals differential requirements for survival in response to chemical challenge. Developmental biology.

Tran, J., Chang, D., Hsu, F., Wang, H., and Guo, Z. (2017). Cross-seeding between Abeta40 and Abeta42 in Alzheimer's disease. FEBS letters 591, 177-185.

Xi, H., Fujiwara, W., Gonzalez, K., Jan, M., Liebscher, S., Van Handel, B., Schenke-Layland, K., and Pyle, A.D. (2017). In Vivo Human Somitogenesis Guides Somite Development from hPSCs. Cell reports 18, 1573-1585.

Yvone, G.M., Zhao-Fleming, H.H., Udeochu, J.C., Chavez-Martinez, C.L., Wang, A., Hirose-Ikeda, M., and Phelps, P.E. (2017). Disabled-1 dorsal horn spinal cord neurons co-express Lmx1b and function in nociceptive circuits. The European journal of neuroscience.

Zhen, A., Rezek, V., Youn, C., Lam, B., Chang, N., Rick, J., Carrillo, M., Martin, H., Kasparian, S., Syed, P., Rice, N., et al. (2017). Targeting type I interferon-mediated activation restores immune function in chronic HIV infection. The Journal of clinical investigation 127, 260-268.